Biography

Dr. Raj joined the UT Southwestern faculty in 2006 after completing his urology training at Duke University Medical Center and his urologic oncology fellowship at Memorial Sloan-Kettering Cancer Center.

He specializes in all aspects of urologic oncology, including the treatment of prostate, bladder, kidney, testis and penile cancers. He is experienced in both open and laparoscopic techniques. He has particular expertise in nerve-sparing radical prostatectomy, complex partial nephrectomy and orthotopic urinary diversion following radical cystectomy for bladder cancer. Dr. Raj’s clinical interests include optimizing oncologic and surgical outcomes for patients with urologic cancers utilizing minimally invasive approaches and multimodality approaches.

He is involved in setting up several clinical trials at UT Southwestern including those examining the role of pre-operative endorectal coil magnetic resonance imaging of prostate cancers and novel neoadjuvant chemotherapeutic approaches for patients with muscle-invasive bladder cancers.

His basic science research laboratory is involved in the development of novel therapeutics against the androgen receptor in prostate cancer. At UT Southwestern, Dr. Raj pioneered and developed several active small molecule compounds, called peptidomimetics against targeting coregulators-nuclear receptors including AR and ER. (Ravindranathan et al, Nature Communications 2013). These compounds have been licensed by a pharmaceutical company, with a goal towards clinical trials by early 2015. Dr. Raj’s laboratory has developed additional compounds targeting the AR in prostate cancer.

Dr. Raj has received peer reviewed funding from the US Department of Defense and Prostate Cancer Foundation. He is a co-recipient of the first ever US Department of Defense Prostate Cancer Research Program Transformative Grant ($US6.8 million). He recently developed a novel ex vivo culture methodology with Dr. Wayne Tilley for evaluation of primary cancer tissues (reviewed recently in Centenera et al, Nature Rev Urology). For further details of his research, please visit the Raj Lab website at http://www.utsouthwestern.edu/labs/raj/

Dr. Raj has received numerous honors for his work throughout his career, including the first prize from the American Urological Association for his laboratory research on prostate cancer. Dr. Raj has authored several high-impact publications in prestigious journals such as the Journal of Clinical Oncology, Lancet Oncology, Cancer and Molecular and Cellular Biology. He serves as reviewer for several peer-reviewed journals in the field of urology and oncology. He was recently elected as only the third urologist ever into the American Society of Clinical Investigation

Education

Medical School
Jefferson Medical School (1997)
Internship/Residency
Duke University Medical Center (2004), Urology
Fellowship
Memorial Sloan Kettering Cancer Institute (2006), Urologic Oncology

Research Interest

  • Androgen receptor signaling
  • Development of primary models of prostate and bladder cancers
  • Development of targeted therapeutics
  • http://www.utsouthwestern.edu/labs/raj/
  • Urologic cancers

Publications

Featured Publications LegendFeatured Publications

Honors & Awards

  • American Society of Clinical Investigation
    Nation's oldest medical honor society (2017)
  • FREEMASONS FOUNDATION CENTRE FOR MENS HEALTH
    Visiting Lectureship, Adelaide Australia (2014)
  • FASEB CONFERENCE MERIT AWARD
    Awarded to the top-rated abstract in steroid signaling (2010)
  • ASCO FOUNDATION MERIT AWARD
    Awarded to the top-rated abstract in genitourinary oncology (2008)
  • ASCO Foundation Merit Award
    Awarded to the top-rated abstracts in prostate cancer, Prostate Cancer Symposium, San Francisco, CA (2006)
  • Society of Memorial Sloan Kettering Research Award
    Awarded for perineural therapeutics and cavernous nerve injury, Society of Memorial Sloan Kettering (2005)
  • AUA/Praecis Gerald P. Murphy Scholar
    Distinction in the study of prostate cancer, AUA Annual Meeting, Orlando FL (2002)
  • AUA Circon Basic Science Research Award (1st Place)
    Laboratory research/ AUA Annual Meeting, Anaheim, CA (2001)
  • Sigma Xi Research Award (1st Place)
    Most outstanding basic science research of the year, Philadelphia Chapter, Sigma Xi Research Society, Philadelphia, PA (1994)

Professional Associations/Affiliations

  • American Society of Clinical Investigation (2017)
  • Society for Basic Urology research (2016)
  • American Association of Cancer Research (2006)
  • American Urological Association (2004)
  • Society of Urologic Oncology