Asaithamby Aroumougame, Ph.D.
Associate Professor

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Asaithamby Aroumougame (a.k.a Thambi), Ph.D.                                  

DEMOGRAPHIC AND PERSONAL INFORMATION

Current Appointments

Associate Professor

Department of Radiation Oncology

University of Texas Southwestern Medical Center at Dallas

 

Contact Information

Division of Molecular Radiation Biology

Department of Radiation Oncology

2201 Inwood Road, NC7.126A                                                                       

Dallas, TX 75390                                                                               

Phone: (214) 648-5175

E-mail: Asaithamby.Aroumougame.@UTsouthwestern.edu

 

Education and Training

2000-2004   Postdoctoral Research Fellow, Lawrence Berkeley National Laboratory, Berkeley, California; Cancer Biology and DNA damage repair

1994-1999   Ph.D.  Banaras Hindu University, India; Cellular and Molecular Biology

1993            M.Phil. Pondicherry University, India; Endocrinology

1992            M.S.    Pondicherry University, India; Life Sciences

1990            B.S.     Pondicherry University, India; Life Sciences

 

Professional Experience

2013-      Assistant Professor (Tenure accruing Track), Department of Radiation Oncology, University of Texas Southwestern Medical Center at Dallas, Texas.

2009-2013 Assistant Professor (Research Track), Department of Radiation Oncology, University of Texas Southwestern Medical Center at Dallas, Texas, Advisor: David J. Chen

2004-2008    Instructor (Junior Faculty), Department of Radiation Oncology, University of Texas Southwestern Medical Center at Dallas, Texas, Advisor: David J. Chen

2002-2004   Postdoctoral Fellow, Department of Life Sciences, Lawrence Berkeley National Laboratory, Berkeley, California, Advisor: David J. Chen

2000-2001 Postdoctoral Fellow, Department of Life Sciences, Lawrence Berkeley National Laboratory, Berkeley, California, Advisor: Shyamala G Harris (Deceased)

1994-1999   Graduate Student, University Grants commission of India, Banaras Hindu University, Varanasi, Uttar Pradesh, India, Advisor: Mahendra K Thakur

Undergraduate

Pondicherry University (1990), Animal Science

Graduate School

Pondicherry University (1992), Animal Science

Graduate School

Banaras Hindu University (1999), Molecular & Cell Biology

• DNA damage response signaling in carcinogenesis
• DNA repair factors in immune response and immunotherapy
• DNA replication in tumorigenesis
• Pathophysiology of Premature Aging Syndrome, specifically Werner Syndrome Protein
• Radiotherapy and heart damage
• Space radiation and Astronauts' health

Featured Publications

RAD51 interconnects between DNA replication, DNA repair and immunity.

Bhattacharya S, Srinivasan K, Abdisalaam S, Su F, Raj P, Dozmorov I, Mishra R, Wakeland EK, Ghose S, Mukherjee S, Asaithamby A Nucleic Acids Res. 2017 Feb

Ionizing radiation and heart risks.

Bhattacharya S, Asaithamby A Semin. Cell Dev. Biol. 2016 Oct 58 14-25

Hypoxia induces heart regeneration in adult mice.

Nakada Y, Canseco DC, Thet S, Abdisalaam S, Asaithamby A, Santos CX, Shah A, Zhang H, Faber JE, Kinter MT, Szweda LI, Xing C, Deberardinis R, Oz O, Lu Z, Zhang CC, Kimura W, Sadek HA Nature 2016 Oct

Time-Lapse Monitoring of DNA Damage Colocalized With Particle Tracks in Single Living Cells.

McFadden CH, Hallacy TM, Flint DB, Granville DA, Asaithamby A, Sahoo N, Akselrod MS, Sawakuchi GO Int. J. Radiat. Oncol. Biol. Phys. 2016 Sep 96 1 221-7

Tumor suppressor protein DAB2IP participates in chromosomal stability maintenance through activating spindle assembly checkpoint and stabilizing kinetochore-microtubule attachments.

Yu L, Shang ZF, Abdisalaam S, Lee KJ, Gupta A, Hsieh JT, Asaithamby A, Chen BP, Saha D Nucleic Acids Res. 2016 Aug

Evaluating biomarkers to model cancer risk post cosmic ray exposure.

Sridharan DM, Asaithamby A, Blattnig SR, Costes SV, Doetsch PW, Dynan WS, Hahnfeldt P, Hlatky L, Kidane Y, Kronenberg A, Naidu MD, Peterson LE, Plante I, Ponomarev AL, Saha J, Snijders AM, Srinivasan K, Tang J, Werner E, Pluth JM Life Sci Space Res (Amst) 2016 Jun 9 19-47

COMT val158met polymorphism and molecular alterations in the human dorsolateral prefrontal cortex: Differences in controls and in schizophrenia.

Shukla AA, Jha M, Birchfield T, Mukherjee S, Gleason K, Abdisalaam S, Asaithamby A, Adams-Huet B, Tamminga CA, Ghose S Schizophr. Res. 2016 Mar

Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathway.

Su F, Bhattacharya S, Abdisalaam S, Mukherjee S, Yajima H, Yang Y, Mishra R, Srinivasan K, Ghose S, Chen DJ, Yannone SM, Asaithamby A Oncotarget 2015 Dec

FANCD2 influences replication fork processes and genome stability in response to clustered DSBs.

Zhu J, Su F, Mukherjee S, Mori E, Hu B, Asaithamby A Cell Cycle 2015 Jun 14 12 1809-22

Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart.

Kimura W, Xiao F, Canseco DC, Muralidhar S, Thet S, Zhang HM, Abdulrahman Y, Chen R, Garcia JA, Shelton JM, Richardson JA, Ashour AM, Asaithamby A, Liang H, Xing C, Lu Z, Zhang CC, Sadek HA Nature 2015 Jun

• Radiation Research Society (2012)