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Asaithamby Aroumougame, Ph.D.

Asaithamby Aroumougame, Ph.D.

Associate Professor

School
Medical School
Department
Radiation Oncology
Graduate Programs
Biomedical Engineering, Cancer Biology
  • Biography

    Download Curriculum Vitae

    Asaithamby Aroumougame (a.k.a. Thambi), Ph.D.                                  

    DEMOGRAPHIC AND PERSONAL INFORMATION

    Current Appointment

    Associate Professor
    Department of Radiation Oncology
    UT Southwestern Medical Center at Dallas

    Contact Information

    Section of Molecular Medicine
    Department of Radiation Oncology
    2201 Inwood Road, NC7.126A                                                                       
    Dallas, TX 75390                                                                               
    Phone: 214-648-5175
    E-mail: asaithamby.aroumougame.@utsouthwestern.edu

    Education and Training

    2000-2004: Postdoctoral Research Fellow, Lawrence Berkeley National Laboratory, Berkeley, California; Cancer Biology and DNA damage repair

    1994-1999: Ph.D., Banaras Hindu University, India; Cellular and Molecular Biology

    1993: M.Phil., Pondicherry University, India; Endocrinology

    1992: M.S., Pondicherry University, India; Life Sciences

    1990: B.S., Pondicherry University, India; Life Sciences

    Professional Experience

    2020-current: Associate Professor, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, Texas. 

    2013-2020: Assistant Professor (Tenure-Accruing Track), Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, Texas.

    2009-2013: Assistant Professor (Research Track), Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, Texas. Advisor: David J. Chen

    2004-2008: Instructor (Junior Faculty), Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, Texas. Advisor: David J. Chen

    2002-2004: Postdoctoral Fellow, Department of Life Sciences, Lawrence Berkeley National Laboratory, Berkeley, California. Advisor: David J. Chen

    2000-2001: Postdoctoral Fellow, Department of Life Sciences, Lawrence Berkeley National Laboratory, Berkeley, California. Advisor: Shyamala G Harris (Deceased)

    1994-1999: Graduate Student, University Grants Commission of India, Banaras Hindu University, Varanasi, Uttar Pradesh, India. Advisor: Mahendra K Thakur

  • Education
    Undergraduate
    Pondicherry University (1990), Animal Science
    Graduate School
    Pondicherry University (1992), Animal Science
    Graduate School
    Banaras Hindu University (1999), Molecular & Cell Biology
  • Research Interest
    • DNA damage response signaling in carcinogenesis
    • DNA repair factors in immune response and immunotherapy
    • DNA replication in tumorigenesis
    • Pathophysiology of Premature Aging Syndrome, specifically Werner Syndrome Protein
    • Radiotherapy and heart damage
    • Space radiation and Astronauts' health
  • Publications
    Cellular senescence and lung cancer prognosis
    Asaithamby A, Shay JW, Minna JD Translational Lung Cancer Research 2022 Oct 11 1982-1987
    NBS1-CtIP-mediated DNA end resection suppresses cGAS binding to micronuclei
    Abdisalaam S, Mukherjee S, Bhattacharya S, Kumari S, Sinha D, Ortega Rodriguez J, Li G, Sadek HA, Krishnan S, Asaithamby A Nucleic acids research 2022 Mar 50 2681-2699
    Mitochondrial fatty acid utilization increases chromatin oxidative stress in cardiomyocytes
    Menendez-Montes I, Abdisalaam S, Xiao F, Lam NT, Mukherjee S, Szweda LI, Asaithamby A, Sadek HA Proceedings of the National Academy of Sciences of the United States of America 2021 Aug 118
    Immunomodulatory effects of radiotherapy
    Kumari S, Mukherjee S, Sinha D, Abdisalaam S, Krishnan S, Asaithamby A International journal of molecular sciences 2020 Nov 21 1-29
    Dysfunctional telomeres trigger cellular senescence mediated by cyclic GMP-AMP synthase
    Abdisalaam S, Bhattacharya S, Mukherjee S, Sinha D, Srinivasan K, Zhu M, Akbay EA, Sadek HA, Shay JW, Asaithamby A Journal of Biological Chemistry 2020 Aug 295 11144-11160
    Pancreatic cancer patients with germline BRCA mutations can benefit from olaparib treatment
    Mukherjee S, Asaithamby A Translational Cancer Research 2020 Apr 9 2154-2156
    Tumor treating fields cause replication stress and interfere with DNA replication fork maintenance: Implications for cancer therapy
    Karanam NK, Ding L, Aroumougame A, Story MD Translational Research 2020 Mar 217 33-46
    Mitochondrial substrate utilization regulates cardiomyocyte cell-cycle progression
    Cardoso AC, Lam NT, Savla JJ, Nakada Y, Pereira AH, Elnwasany A, Menendez-Montes I, Ensley EL, Bezan Petric U, Sharma G, Sherry AD, Malloy CR, Khemtong C, Kinter MT, Tan WL, Anene-Nzelu CG, Foo RS, Nguyen NU, Li S, Ahmed MS, Elhelaly WM, Abdisalaam S, Asaithamby A, Xing C, Kanchwala M, Vale G, Eckert KM, Mitsche MA, McDonald JG, Hill JA, Huang L, Shaul PW, Szweda LI, Sadek HA Nature Metabolism 2020 Feb 2 167-178
    Isolation of time-dependent DNA damage induced by energetic carbon ions and their fragments using fluorescent nuclear track detectors
    McFadden CH, Rahmanian S, Flint DB, Bright SJ, Yoon DS, O’Brien DJ, Asaithamby A, Abdollahi A, Greilich S, Sawakuchi GO Medical physics 2020 Jan 47 272-281
    Nonhomologous End Joining Is More Important Than Proton Linear Energy Transfer in Dictating Cell Death
    Bright SJ, Flint DB, Chakraborty S, McFadden CH, Yoon DS, Bronk L, Titt U, Mohan R, Grosshans DR, Sumazin P, Shaitelman SF, Asaithamby A, Sawakuchi GO International Journal of Radiation Oncology Biology Physics 2019 Dec 105 1119-1125
  • Professional Associations/Affiliations
    • Radiation Research Society (2012)