Research Interest

  • Multidrug resistance, Gram-negative infections, Pharmacokinetics, Pharmacodynamics, Beta-lactamase inhibitors


Featured Publications LegendFeatured Publications

Minimal Cerebrospinal Concentration of Miltefosine Despite Therapeutic Plasma Levels During the Treatment of Amebic Encephalitis.
Monogue ML, Watson D, Alexander JS, Cavuoti D, Doyle LM, Wang MZ, Prokesch BC, Antimicrob. Agents Chemother. 2019 Nov
Pharmacokinetics-pharmacodynamics of ?-lactamase inhibitors: are we missing the target?
Monogue ML, Nicolau DP, Expert Rev Anti Infect Ther 2019 Aug 17 8 571-582
In Vivo Efficacy of WCK 5222 (Cefepime-Zidebactam) against Multidrug-Resistant Pseudomonas aeruginosa in the Neutropenic Murine Thigh Infection Model.
Monogue ML, Tabor-Rennie J, Abdelraouf K, Nicolau DP, Antimicrob. Agents Chemother. 2019 07 63 7
Efficacy of Humanized Cefiderocol Exposures over 72 Hours against a Diverse Group of Gram-Negative Isolates in the Neutropenic Murine Thigh Infection Model.
Stainton SM, Monogue ML, Tsuji M, Yamano Y, Echols R, Nicolau DP Antimicrob. Agents Chemother. 2019 Feb 63 2
Nafcillin versus cefazolin for the treatment of methicillin-susceptible Staphylococcus aureus bacteremia.
Monogue ML, Ortwine JK, Wei W, Eljaaly K, Bhavan KP J Infect Public Health 2018 Sep - Oct 11 5 727-731
Efficacy of Meropenem with a Novel Non-?-Lactam-?-Lactamase Inhibitor, Nacubactam, against Gram-Negative Organisms Exhibiting Various Resistance Mechanisms in a Murine Complicated Urinary Tract Infection Model.
Monogue ML, Giovagnoli S, Bissantz C, Zampaloni C, Nicolau DP Antimicrob. Agents Chemother. 2018 Sep 62 9
Assessment of in vivo efficacy of eravacycline against Enterobacteriaceae exhibiting various resistance mechanisms: a dose-ranging study and pharmacokinetic/pharmacodynamic analysis.
Thabit AK, Monogue ML, Newman JV, Nicolau DP Int. J. Antimicrob. Agents 2018 May 51 5 727-732
Antibacterial activity of ceftolozane/tazobactam alone and in combination with other antimicrobial agents against MDR Pseudomonas aeruginosa.
Monogue ML, Nicolau DP J. Antimicrob. Chemother. 2018 Apr 73 4 942-952
Pharmacodynamics of cefiderocol, a novel siderophore cephalosporin, in a Pseudomonas aeruginosa neutropenic murine thigh model.
Ghazi IM, Monogue ML, Tsuji M, Nicolau DP Int. J. Antimicrob. Agents 2018 Feb 51 2 206-212
Physical compatibility of fosfomycin for injection with select i.v. drugs during simulated Y-site administration.
Monogue ML, Almarzoky Abuhussain SS, Kuti JL, Nicolau DP Am J Health Syst Pharm 2018 Jan 75 1 e36-e44