Biography

Kin Man Au, Ph.D., is an Assistant Professor of Radiation Oncology at UT Southwestern Medical Center. He is part of the Department of Radiation Oncology’s Section of Molecular Radiation Biology.

Dr. Man Au earned a master’s degree in chemistry at the University of Sheffield (UK) in 2007. He also attended graduate school there and received a Ph.D. in chemistry in 2013. His Ph.D. thesis was titled, “Biomedical Applications of Polypyrrole Nanoparticles.”

Afterward, Dr. Man Au completed his postdoctoral research at the University of North Carolina at Chapel Hill and then accepted a faculty position at UT Southwestern Medical Center. His research interests include cancer, drug delivery, polymer chemistry, biomedical imaging, photothermal therapy, radiotherapy and nuclear medicine, and cancer immunotherapy.

Research Interest

  • Autoimmune diseases
  • Biomaterials
  • Biomedical imaging
  • Cancer
  • Cancer immunotherapy
  • Chemoradiotherapy adoptive cell therapy
  • Chemotherapy
  • Drug delivery
  • In vivo animal model
  • Low-cost point-of-care diagnostic test
  • Photothermal therapy
  • Polymer chemistry
  • Radiotherapy and nuclear medicine

Publications

An injectable subcutaneous colon-specific immune niche for the treatment of ulcerative colitis
Au KM, Wilson JE, Ting JP, Wang AZ Nature Biomedical Engineering 2023
Immune Checkpoint Ligand Bioengineered Schwann Cells as Antigen-Specific Therapy for Experimental Autoimmune Encephalomyelitis
Au KM, Tisch R, Wang AZ Advanced Materials 2022 Feb 34
In Vivo Bioengineering of Beta Cells with Immune Checkpoint Ligand as a Treatment for Early-Onset Type 1 Diabetes Mellitus
Au KM, Tisch R, Wang AZ ACS Nano 2021 Dec 15 19990-20002
Immune Checkpoint-Bioengineered Beta Cell Vaccine Reverses Early-Onset Type 1 Diabetes
Au KM, Medik Y, Ke Q, Tisch R, Wang AZ Advanced Materials 2021 Jun 33
Co-delivery of etoposide and cisplatin in dual-drug loaded nanoparticles synergistically improves chemoradiotherapy in non-small cell lung cancer models
Zhang M, Hagan CT, Foley H, Tian X, Yang F, Au KM, Mi Y, Medik Y, Roche K, Wagner K, Rodgers Z, Min Y, Wang AZ Acta Biomaterialia 2021 Apr 124 327-335
Trispecific natural killer cell nanoengagers for targeted chemoimmunotherapy
Au KM, Par SI, Wa AZ Science Advances 2020 Jul 6
Pretargeted delivery of PI3K/mTOR small-molecule inhibitor–loaded nanoparticles for treatment of non-Hodgkin’s lymphoma
Au KM, Wang AZ, Park SI Science Advances 2020 Apr 6
High-Performance Concurrent Chemo-Immuno-Radiotherapy for the Treatment of Hematologic Cancer through Selective High-Affinity Ligand Antibody Mimic-Functionalized Doxorubicin-Encapsulated Nanoparticles
Au KM, Balhorn R, Balhorn MC, Park SI, Wang AZ ACS Central Science 2019 Jan 5 122-144
Nanoparticle co-delivery of wortmannin and cisplatin synergistically enhances chemoradiotherapy and reverses platinum resistance in ovarian cancer models
Zhang M, Hagan CT, Min Y, Foley H, Tian X, Yang F, Mi Y, Au KM, Medik Y, Roche K, Wagner K, Rodgers Z, Wang AZ Biomaterials 2018 Jul 169 1-10
Bespoke Pretargeted Nanoradioimmunotherapy for the Treatment of Non-Hodgkin Lymphoma
Au KM, Tripathy A, Lin CP, Wagner K, Hong S, Wang AZ, Park SI ACS Nano 2018 Feb 12 1544-1563

Honors & Awards

  • Raleigh Award for Excellence in Biology Research, Department of Radiation Oncology, University of North Carolina (UNC)-Chapel Hill, NC
    (2020)
  • The Wharton Prize, The University of Sheffield (UK)
    (2019)
  • Best Poster Award, UK Macro Group 3rd International Polymer Chemistry Conference
    (2012)
  • The Wharton Prize, University of Sheffield (UK)
    (2004)

Professional Associations/Affiliations

  • American Chemical Society, Member (2007)