Featured Publications LegendFeatured Publications

Recent endeavors in MECP2 gene transfer for gene therapy of Rett syndrome.
Sinnett SE, Gray SJ Discov Med 2017 Oct 24 132 153-159
Development of a Novel AAV Gene Therapy Cassette with Improved Safety Features and Efficacy in a Mouse Model of Rett Syndrome.
Gadalla KKE, Vudhironarit T, Hector RD, Sinnett S, Bahey NG, Bailey MES, Gray SJ, Cobb SR Mol Ther Methods Clin Dev 2017 Jun 5 180-190
Improved MECP2 Gene Therapy Extends the Survival of MeCP2-Null Mice without Apparent Toxicity after Intracisternal Delivery.
Sinnett SE, Hector RD, Gadalla KKE, Heindel C, Chen D, Zaric V, Bailey MES, Cobb SR, Gray SJ Mol Ther Methods Clin Dev 2017 Jun 5 106-115
Past strategies and future directions for identifying AMP-activated protein kinase (AMPK) modulators.
Sinnett SE, Brenman JE, Pharmacol. Ther. 2014 Jul 143 1 111-8
A High Throughput Assay for Discovery of Small Molecules that Bind AMP-activated Protein Kinase (AMPK).
Sinnett SE, Sexton JZ, Brenman JE, Curr Chem Genom Transl Med 2013 7 30-8
Effects of a stressor and corticotrophin releasing factor on ethanol deprivation-induced ethanol intake and anxiety-like behavior in alcohol-preferring P rats.
Knapp DJ, Overstreet DH, Huang M, Wills TA, Whitman BA, Angel RA, Sinnett SE, Breese GR, Psychopharmacology (Berl.) 2011 Nov 218 1 179-89

Honors & Awards

  • ASGCT Travel Award
  • Travel Award from UNC's Graduate Student Federation

Professional Associations/Affiliations

  • American Society of Gene & Cell Therapy, Associate Member (2015, 2017)