Biography

Dr. Liu received her Ph.D. from University of Rostock, Germany. She completed postdoc training and became a faculty at UT Southwestern.

Dr. Liu is interested in molecular mechanism of TNF induced necroptosis and pathogen mediated inflammation, cancer and autoimmune diseases.

Education
Undergraduate
(2016), Microbiology
Graduate School
(2016), Molecular Biology
Graduate School
(2016), None
Graduate School
(2016), Biochemistry

Research Interest
  • Cancer
  • Inflammation
  • Necroptosis

Publications

Featured Publications LegendFeatured Publications

Necroptosis-blocking compound NBC1 targets heat shock protein 70 to inhibit MLKL polymerization and necroptosis.
Johnston AN, Ma Y, Liu H, Liu S, Hanna-Addams S, Chen S, Chen C, Wang Z, Proc. Natl. Acad. Sci. U.S.A. 2020 Mar 117 12 6521-6530
CK1a, CK1d, and CK1e are necrosome components which phosphorylate serine 227 of human RIPK3 to activate necroptosis.
Hanna-Addams S, Liu S, Liu H, Chen S, Wang Z, Proc. Natl. Acad. Sci. U.S.A. 2020 Jan 117 4 1962-1970
MLKL forms disulfide bond-dependent amyloid-like polymers to induce necroptosis.
Liu S, Liu H, Johnston A, Hanna-Addams S, Reynoso E, Xiang Y, Wang Z Proc. Natl. Acad. Sci. U.S.A. 2017 Aug
The erythropoietin receptor is a downstream effector of Klotho-induced cytoprotection.
Hu MC, Shi M, Cho HJ, Zhang J, Pavlenco A, Liu S, Sidhu S, Huang LJ, Moe OW Kidney Int. 2013 May
Lingual antimicrobial peptide and IL-8 expression are oppositely regulated by the antagonistic effects of NF-?B p65 and C/EBPß in mammary epithelial cells.
Liu S, Shi X, Bauer I, Günther J, Seyfert HM, Mol. Immunol. 2011 Mar 48 6-7 895-908
Salmonid Tollip and MyD88 factors can functionally replace their mammalian orthologues in TLR-mediated trout SAA promoter activation.
Rebl A, Rebl H, Liu S, Goldammer T, Seyfert HM, Dev. Comp. Immunol. 2011 Jan 35 1 81-7
C/EBP-beta drives expression of the nutritionally regulated promoter IA of the acetyl-CoA carboxylase-alpha gene in cattle.
Shi X, Liu S, Metges CC, Seyfert HM, Biochim. Biophys. Acta 2010 Aug 1799 8 561-7
Stimulated expression of TNF-alpha and IL-8, but not of lingual antimicrobial peptide reflects the concentration of pathogens contacting bovine mammary epithelial cells.
Günther J, Liu S, Esch K, Schuberth HJ, Seyfert HM, Vet. Immunol. Immunopathol. 2010 May 135 1-2 152-157
Molecular cloning and characterization of a laccase gene from the basidiomycete Fome lignosus and expression in Pichia pastoris.
Liu W, Chao Y, Liu S, Bao H, Qian S, Appl. Microbiol. Biotechnol. 2003 Dec 63 2 174-81