Asaithamby Aroumougame, Ph.D. Associate Professor School Medical School Department Radiation Oncology Graduate Programs Biomedical Engineering, Cancer Biology Biography Download Curriculum Vitae Asaithamby Aroumougame (a.k.a. Thambi), Ph.D. DEMOGRAPHIC AND PERSONAL INFORMATION Current Appointment Associate Professor Department of Radiation Oncology UT Southwestern Medical Center at Dallas Contact Information Section of Molecular Medicine Department of Radiation Oncology 2201 Inwood Road, NC7.126A Dallas, TX 75390 Phone: 214-648-5175 E-mail: asaithamby.aroumougame.@utsouthwestern.edu Education and Training 2000-2004: Postdoctoral Research Fellow, Lawrence Berkeley National Laboratory, Berkeley, California; Cancer Biology and DNA damage repair 1994-1999: Ph.D., Banaras Hindu University, India; Cellular and Molecular Biology 1993: M.Phil., Pondicherry University, India; Endocrinology 1992: M.S., Pondicherry University, India; Life Sciences 1990: B.S., Pondicherry University, India; Life Sciences Professional Experience 2020-current: Associate Professor, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, Texas. 2013-2020: Assistant Professor (Tenure-Accruing Track), Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, Texas. 2009-2013: Assistant Professor (Research Track), Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, Texas. Advisor: David J. Chen 2004-2008: Instructor (Junior Faculty), Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, Texas. Advisor: David J. Chen 2002-2004: Postdoctoral Fellow, Department of Life Sciences, Lawrence Berkeley National Laboratory, Berkeley, California. Advisor: David J. Chen 2000-2001: Postdoctoral Fellow, Department of Life Sciences, Lawrence Berkeley National Laboratory, Berkeley, California. Advisor: Shyamala G Harris (Deceased) 1994-1999: Graduate Student, University Grants Commission of India, Banaras Hindu University, Varanasi, Uttar Pradesh, India. Advisor: Mahendra K Thakur Education Undergraduate Pondicherry University (1990), Animal Science Graduate School Pondicherry University (1992), Animal Science Graduate School Banaras Hindu University (1999), Molecular & Cell Biology Research Interest DNA damage response signaling in carcinogenesis DNA repair factors in immune response and immunotherapy DNA replication in tumorigenesis Pathophysiology of Premature Aging Syndrome, specifically Werner Syndrome Protein Radiotherapy and heart damage Space radiation and Astronauts' health Publications Cellular senescence and lung cancer prognosis Asaithamby A, Shay JW, Minna JD Translational Lung Cancer Research 2022 Oct 11 1982-1987 NBS1-CtIP-mediated DNA end resection suppresses cGAS binding to micronuclei Abdisalaam S, Mukherjee S, Bhattacharya S, Kumari S, Sinha D, Ortega Rodriguez J, Li G, Sadek HA, Krishnan S, Asaithamby A Nucleic acids research 2022 Mar 50 2681-2699 Mitochondrial fatty acid utilization increases chromatin oxidative stress in cardiomyocytes Menendez-Montes I, Abdisalaam S, Xiao F, Lam NT, Mukherjee S, Szweda LI, Asaithamby A, Sadek HA Proceedings of the National Academy of Sciences of the United States of America 2021 Aug 118 Immunomodulatory effects of radiotherapy Kumari S, Mukherjee S, Sinha D, Abdisalaam S, Krishnan S, Asaithamby A International journal of molecular sciences 2020 Nov 21 1-29 Dysfunctional telomeres trigger cellular senescence mediated by cyclic GMP-AMP synthase Abdisalaam S, Bhattacharya S, Mukherjee S, Sinha D, Srinivasan K, Zhu M, Akbay EA, Sadek HA, Shay JW, Asaithamby A Journal of Biological Chemistry 2020 Aug 295 11144-11160 Pancreatic cancer patients with germline BRCA mutations can benefit from olaparib treatment Mukherjee S, Asaithamby A Translational Cancer Research 2020 Apr 9 2154-2156 Tumor treating fields cause replication stress and interfere with DNA replication fork maintenance: Implications for cancer therapy Karanam NK, Ding L, Aroumougame A, Story MD Translational Research 2020 Mar 217 33-46 Mitochondrial substrate utilization regulates cardiomyocyte cell-cycle progression Cardoso AC, Lam NT, Savla JJ, Nakada Y, Pereira AH, Elnwasany A, Menendez-Montes I, Ensley EL, Bezan Petric U, Sharma G, Sherry AD, Malloy CR, Khemtong C, Kinter MT, Tan WL, Anene-Nzelu CG, Foo RS, Nguyen NU, Li S, Ahmed MS, Elhelaly WM, Abdisalaam S, Asaithamby A, Xing C, Kanchwala M, Vale G, Eckert KM, Mitsche MA, McDonald JG, Hill JA, Huang L, Shaul PW, Szweda LI, Sadek HA Nature Metabolism 2020 Feb 2 167-178 Isolation of time-dependent DNA damage induced by energetic carbon ions and their fragments using fluorescent nuclear track detectors McFadden CH, Rahmanian S, Flint DB, Bright SJ, Yoon DS, O’Brien DJ, Asaithamby A, Abdollahi A, Greilich S, Sawakuchi GO Medical physics 2020 Jan 47 272-281 Nonhomologous End Joining Is More Important Than Proton Linear Energy Transfer in Dictating Cell Death Bright SJ, Flint DB, Chakraborty S, McFadden CH, Yoon DS, Bronk L, Titt U, Mohan R, Grosshans DR, Sumazin P, Shaitelman SF, Asaithamby A, Sawakuchi GO International Journal of Radiation Oncology Biology Physics 2019 Dec 105 1119-1125 Results 1-10 of 62 1 2 3 4 5 Next Last Professional Associations/Affiliations Radiation Research Society (2012)