Jeffrey Elliott, M.D.

Medical School	Washington University School of Medicine (1988)
Internship	Jewish Hospital of St. Louis (1989), Internal Medicine
Residency	Barnes-Jewish Hospital (1992), Neurology
Fellowship	BJC Healthcare (1994), Neuromuscular Disease

• Neurology
• Neuromuscular Disorders
• Neurosciences

• Primary Interests
• Acid Maltase Deficiency
• Amytrophic Lateral Sclerosis (ALS) (MDA)
• Becker Muscular Dystrophy
• Bulbar Palsy
• Charcot-Marie-Tooth (CMT)(MDA)
• Congenital Myopathy
• Debrancher Enzyme Deficiency (MDA)
• Dermatomyositis (MDA)
• Duchenne Disease (MDA)
• Dystrophy (MDA)
• Eaton Lambert Syndrome (MDA)
• Facioscapulohumeral Muscular Dystrophy (MDA)
• Fasciculations
• Friedreich's Ataxia (MDA)
• Inclusion Body Myositis(MDA)
• Inflammatory Myopathy (MDA)
• Keams-Sayre Syndrome (MDA)
• Lambert Eaton Syndrome (MDA)
• Lou Gehrig's Disease (MDA)
• McArdles Disease (MDA)
• Metabolic Myopathy (MDA)
• Mitochondrial Myopathy (MDA)
• Mononeuritis
• Motor Neuron Disease (MDA)
• Muscular Atrophy
• Muscular Dystrophy (MDA)
• Myasthenia Gravis (MG) (MDA)
• Myoglobinuria
• Myopathy
• Myositis (MDA)
• Nemaline Myopathy (MDA)
• Phosphofructokinase Deficiency (MDA)
• Polymyositis (ILD)(MDA)
• Post-Polio Syndromes
• Primary Lateral Sclerosis (MDA)
• Rhabdomyolysis
• Spinal Muscular Atrophy (MDA)
• Thompsen's Disease (MDA)
• Thyroid Myopathy

Featured Publications

"Disease Progression in Transgenic model of familial amyotrophic latera sclerosis is dependent on both Neuronal and non-neuronal zinc binding proteins."o

K Puttparthi, WL Gitomer U Krishnan, M Son, B Rajendran, and JL Elliott Journal of Neuroscience, October 2002 22: 8790-8796

"Upregulation of cytokine expression in a transgenic model of familial amyotrophic lateral sclerosis"

Elliott JL, Molecular Brain Research 2001 95: 172-178

"Glutamate transorter EAAT-2 splice variants occur not only in ALS, but also in AD and controls"

Honig LS, Chambliss D, Bigio E, Carroll S, Elliott JL Neurology 2000 55: 1082-1088

"Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoreuron degeneration"

Gong YH, Parsadanian A, Andreeva A, Snider WD, Elliott,JL, Journal of Neuroscience, 2000 20(2): 660-665

"Motor Neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury"

Reaume AG, Elliott JL, Hoffman EK, et al, Nature Genetics 1996 13: 43-47

"Redox susceptibility of SOD1 mutants is associated with the differential resonse to CCS over-expression in vivo"

Son M, Fu Q, Puttaparthi K, Matthews CM and Elliott JL. Neurobiology of Disease 2009 In press

"Isolated Cytochrome c oxidase deficiency in G93A SOD1 mice overexpressing CCS protein"

Son, M., Leary, S.C., Romain, N., Pierrel, F., Winge, D.R., Haller, R.G., and Elliott, J.L., The Journal of Biological Chemistry May 2008 283: 12267-12275,

"Biological effects of CCS in the absence of SOD1 enzyme activation: implications for disease in a mouse model of ALS"

Proescher JB, Son M, Elliott JL, Culotta VC, Human Molecular Genetics 2008 17: 1728-1737.

"Assessing the role of immuno-prpteasomes in a mouse model of familial ALS"

K Puttaparthis and JL Elliott Experimental Neurology July 2007 206: 53-58

"Assessing the role of immuno-proteasomes in a mouse model of familial ALS"

K Puttaparthi and JL Elliott, Experimental Neurology July 2007 206: 53-58

• President Research Council Distinguished Young Researcher Award
  (1998)

• American Academy of Neurology
• American Association of Electrodiagnostic Medicine
• Society for Neuroscience