Dr. Reynolds received her undergraduate training in biochemistry at Rice University. She completed her Ph.D. in biophysics with Dr. Tracy Handel at the University of California, Berkeley in 2006, where she studied the computational design of protein-protein interfaces. She then completed a postdoctoral fellowship in the lab of Dr. Rama Ranganathan at UT Southwestern, where she studied on the evolution and engineering of allosteric communication between proteins.
- molecular evolution
- protein regulation and inter-protein communication
- statistical analysis of genomes and prediction of functional interactions
- Evolution-based design of proteins.
- Reynolds KA, Russ WP, Socolich M, Ranganathan R Meth. Enzymol. 2013 523 213-35
- Hot spots for allosteric regulation on protein surfaces.
- Reynolds KA, McLaughlin RN, Ranganathan R Cell 2011 Dec 147 7 1564-75
- Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface.
- Reynolds KA, Hanes MS, Thomson JM, Antczak AJ, Berger JM, Bonomo RA, Kirsch JF, Handel TM J. Mol. Biol. 2008 Oct 382 5 1265-75
- An object-oriented library for computational protein design.
- Chowdry AB, Reynolds KA, Hanes MS, Voorhies M, Pokala N, Handel TM J Comput Chem 2007 Nov 28 14 2378-88
- Structural and computational characterization of the SHV-1 beta-lactamase-beta-lactamase inhibitor protein interface.
- Reynolds KA, Thomson JM, Corbett KD, Bethel CR, Berger JM, Kirsch JF, Bonomo RA, Handel TM J. Biol. Chem. 2006 Sep 281 36 26745-53