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  • Structure of mammalian endolysosomal TRPML1 channel in nanodiscs – Bai Lab

    https://baistructurelab.org/publication/structure-of-mammalian-endolysosomal-trpml1-channel-in-nanodiscs/

    Login Home Research Structure Gallery Lab Members Publications Search Menu Menu Structure of mammalian endolysosomal TRPML1 channel in nanodiscs Qingfeng Chen*, Ji She*, Weizhong Zeng, Jiangtao Guo, Haoxing Xu, Xiao-chen Bai †, Youxing Jiang†.. Structure of mammalian endolysosomal TRPML1 channel in n…

  • Structures of the human mitochondrial ribosome in native states of assembly – Bai Lab

    https://baistructurelab.org/publication/structures-of-the-human-mitochondrial-ribosome-in-native-states-of-assembly/

    Login Home Research Structure Gallery Lab Members Publications Search Menu Menu Structures of the human mitochondrial ribosome in native states of assembly Alan Brown, Sorbhi Rathore, Dari Kimanius, Shintaro Aibara, Xiao-chen Bai , Joanna Rorbach, Alexey Amunts†, V Ramakrishnan†. Structures of the hu…

  • Cell type-specific inference of differential expression in spatial transcriptomics

    https://haiqichenlab.github.io/pubpdfs/C-SIDE.pdf

    Articles https://doi.org/10.1038/s41592-022-01575-3 1Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, USA. 2Broad Institute of MIT and Harvard, Cambridge, MA, USA. 3Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA. 4Department of Pathology, Br…

  • Efficient, continuous mutagenesis in human cells using a pseudo-random DNA editor

    https://haiqichenlab.github.io/pubpdfs/TRACE.pdf

    Brief Communication https://doi.org/10.1038/s41587-019-0331-8 1Broad Institute of MIT and Harvard, Cambridge, MA, USA. 2Biophysics Program, Harvard University, Boston, MA, USA. 3Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA. 4MIT M…

  • Cell polarity and planar cell polarity (PCP) in spermatogenesis

    https://haiqichenlab.github.io/pubpdfs/Seminars.pdf

    R C H C a 1 b c a A R R A A K T P S S B C 1 t d t N ( h 1 Seminars in Cell & Developmental Biology 81 (2018) 71–77 Contents lists available at ScienceDirect Seminars in Cell & Developmental Biology j ourna l h o me page: www.elsev ier .com/ locate /semcdb eview ell polarity …

  • Yi Ren | Zhang CNL

    https://www.zhang-cnl.org/team/yi-ren

    top of page The Computational Neuroscience Lab Home Research Team Publications Positions Contact More Use tab to navigate through the menu items. < Back Yi Ren Graduate student Yi.Ren (at) utsouthwestern.edu © Zhang Lab of Computational Neuroscience This website reflects only the views of the Zhang L…

  • Single-Cell Transcriptomics Reveal Disrupted Kidney Filter Cell-Cell Interactions after Early and Selective Podocyte Injury

    https://haiqichenlab.github.io/pubpdfs/AmJ_Pathol.pdf

    The American Journal of Pathology, Vol. 192, No. 2, February 2022 ajp.amjpathol.org CELL INJURY, REPAIR, AGING, AND APOPTOSIS Single-Cell Transcriptomics Reveal Disrupted Kidney Filter Cell-Cell Interactions after Early and Selective Podocyte Injury Abbe R. Clark,*y Jamie Marshall,* Yiming Zhou,*y …

  • Vangl2 regulates spermatid planar cell polarity through microtubule (MT)-based cytoskeleton in the rat testis

    https://haiqichenlab.github.io/pubpdfs/Cell_Death.pdf

    Chen et al. Cell Death and Disease (2018) 9:340 DOI 10.1038/s41419-018-0339-x Cell Death & Disease ART ICLE Open Ac ce s s Vangl2 regulates spermatid planar cell polarity through microtubule (MT)-based cytoskeleton in the rat testis Haiqi Chen1, Xiang Xiao 2, Wing-yee Lui3, Will M. Lee3 and C. Ya…

  • In vivo hypermutation and continuous evolution

    https://haiqichenlab.github.io/pubpdfs/Primer.pdf

    Throughout the history of life, evolution has relied on the basic processes of random mutation and natural selection to yield a diverse array of biomolecules with remarkable functions. The field of directed evolution has long sought to leverage the power of evolution to engineer novel biomolecul…

  • How to make a spermbot

    https://haiqichenlab.github.io/pubpdfs/How_to_make_a_spermbot.pdf

    How to make a spermbot Haiqi Chen 10/03/2023 This essay is a thought experiment on making a spermbot - a microrobot technology created by coupling genetically modified sperm cells with various types of payloads for targeted deliveries in a living system. Although this bot doesn’t yet exist,…