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  • Post-squalene Cholesterol Biosynthetic Pathways | Mitsche Lab | UT Southwestern, Dallas, Texas

    https://labs.utsouthwestern.edu/mitsche-lab/research/post-squalene-cholesterol-biosynthetic-pathways

    Skip to main content Post-squalene Cholesterol Biosynthetic Pathways There has been an outstanding debate over the route of cholesterol biosynthesis since it was first discovered in the 1950s. Two alternative pathways have been proposed, the Bloch and Kandutsch-Russell pathways. Using deuterium water…

  • Lee Lab | UT Southwestern, Dallas, Texas

    https://labs.utsouthwestern.edu/lee-lab

    Our research is aimed at innovating and translating computational technology to advance biomedical research and medical diagnoses/treatments.

  • Research | Friedman Lab | UT Southwestern, Dallas, Texas

    https://labs.utsouthwestern.edu/friedman-lab/research

    Skip to main content Research Cristae Organization Positioning of mitochondrial cristae and functions of the MICOS complex Cristae membranes are the hallmark feature of mitochondria, giving them their distinctive appearance in electron microscopy images. Cristae are home to the respiratory complexes …

  • Flux Technology | Mitsche Lab | UT Southwestern, Dallas, Texas

    https://labs.utsouthwestern.edu/mitsche-lab/research/flux-technology

    Skip to main content Flux Technology Measuring the rate of lipid biosynthesis has traditionally been done using radio-isotope labeling. While this technology is very sensitive, it is inherently dangerous due to the radioactivity and fairly non specific. Stable-isotope labeling provides an alternative…

  • Research | CMRU - Cardiometabolic Research Unit | UT Southwestern, Dallas, Texas

    https://labs.utsouthwestern.edu/cmru-cardiometabolic-research-unit/research

    Current Research projects in the Cardiometabolic Research Unit

  • Big Data, Risk Prediction and Epidemiology | CMRU - Cardiometabolic Research Unit | UT Southwestern, Dallas, Texas

    https://labs.utsouthwestern.edu/cmru-cardiometabolic-research-unit/research/big-data-risk-prediction-and-epidemiology

    Skip to main content Big Data, Risk Prediction and Epidemiology Our lab uses big-data approaches to predict risk of heart failure that can be used to identify who may benefit from effective preventive therapies. We have also developed novel risk-prediction models to better predict risk of cardiovascu…

  • SoRelle Lab | UT Southwestern, Dallas, Texas

    https://labs.utsouthwestern.edu/sorelle-lab

    Our lab aim is to discover and translate findings into diagnostic and therapeutic solutions for patients with allergy.

  • Biomarkers and Metabolomics | CMRU - Cardiometabolic Research Unit | UT Southwestern, Dallas, Texas

    https://labs.utsouthwestern.edu/cmru-cardiometabolic-research-unit/research/biomarkers-and-metabolomics

    Our lab has investigated the strengths and limitations of current biomarkers for risk prediction and cardiovascular screening.

  • Fetzer Lab | UT Southwestern, Dallas, Texas

    https://labs.utsouthwestern.edu/fetzer-lab

    CACTUS lab constitutes a group of like-minded physicians, scientists, and technical experts dedicated to the advancement of clinical imaging, translation and technical research, and image-guided intervention in ultrasound.

  • Sorrell Lab | UT Southwestern, Dallas, Texas

    https://labs.utsouthwestern.edu/sorrell-lab

    The Sorrell Laboratory utilizes integrative approaches that include metabolomics, transcriptomics, organoid cultures, live microcopy, and animal models, to investigate fundamental pathways that control the uptake of nutrients and the biosynthesis of macromolecules in proliferative cells.