Search Results for ""

• Meet the PI | Brown Lab | UT Southwestern, Dallas, Texas

  https://labs.utsouthwestern.edu/brown-lab/meet-pi

  Meet our Principal Investigator, E. Sherwood Brown, MD, PhD, MBA

  

• Publications | Brown Lab | UT Southwestern, Dallas, Texas

  https://labs.utsouthwestern.edu/brown-lab/publications

  Publications of Psychoneuroendocrine Research Lab

  

• Research | Huber Lab | UT Southwestern, Dallas, Texas

  https://labs.utsouthwestern.edu/huber-lab/research

  The Huber lab is focused on understanding how activity-regulated transcription and translation in neurons controls synapse and circuit plasticity and development. 

  

• Mechanisms of circuit dysfunction in mouse autism models and the role of synaptic scaffolding proteins | Huber Lab | UT Southwestern, Dallas, Texas

  https://labs.utsouthwestern.edu/huber-lab/research/mechanisms-circuit-dysfunction-mouse-autism-models-and-role-synaptic-scaffolding

  In addition to our work on mechanisms of FMRP function at synapses, we have also contributed to the understanding of circuit dysfunction in Fragile X Syndrome, with a goal to reveal mechanisms of FMRP function in the brain, but also to identify therapeutic targets to correct and restore circuit function in diseases such as FXS and related autistic disorders.

  

• Regulation of Anchorage Signals Through Shc | Terada Lab | UT Southwestern, Dallas, Texas

  https://labs.utsouthwestern.edu/terada-lab/research/regulation-anchorage-signals-through-shc

  Specialized metazoan cells have diverse functions which require them to interact differently with the body’s matrix scaffolds.

  

• News | Huber Lab | UT Southwestern, Dallas, Texas

  https://labs.utsouthwestern.edu/huber-lab/news

  Huber Lab News

  

• Mechanisms of experience and activity-dependent development of synapses and circuits by genes linked to neurodevelopmental disorders | Huber Lab | UT Southwestern, Dallas, Texas

  https://labs.utsouthwestern.edu/huber-lab/research/mechanisms-experience-and-activity-dependent-development-synapses-and-circuits

  We study the cellular, synaptic and molecular mechanisms of synapse and circuit development and how this is regulated by genes implicated in autism and schizophrenia.

  

• Reactive Oxidants and Signaling | Terada Lab | UT Southwestern, Dallas, Texas

  https://labs.utsouthwestern.edu/terada-lab/research/reactive-oxidants-and-signaling

  The study of reactive oxidant species (ROS) has long been dominated by the concept that ROS are primarily of biomedical importance because of their capacity to initiate damaging reactions that cause oxidative stress and cellular injury.

  

• Research | Wu (Jun) Lab | UT Southwestern, Dallas, Texas

  https://labs.utsouthwestern.edu/wu-jun-lab/research

  Interested in our research? Learn more about the work we’re doing at Jun Wu Lab

  

• Localized, dendritic protein synthesis and its role in synaptic plasticity and neurodevelopmental disorders | Huber Lab | UT Southwestern, Dallas, Texas

  https://labs.utsouthwestern.edu/huber-lab/research/localized-dendritic-protein-synthesis-and-its-role-synaptic-plasticity-and

  To mediate long-term changes in function and structure of such numerous contacts, somewhat independently, neurons utilize “localized” protein synthesis within dendrites and near synapses.