Guiyang Hao, Ph.D.
Assistant Professor

Undergraduate

Beijing Normaluniversity-China (2000), Chemistry

Graduate School

Beijing Normaluniversity-China (2005), Chemistry

• Design and evaluate molecular imaging probes for cancer, neurological disorders, and cardiovascular/metabolic diseases via positron emission tomography (PET), single photon emission computed tomography (SPECT), and fluorescence imaging.

Featured Publications

PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression.

Tang H, Liang Y, Anders RA, Taube JM, Qiu X, Mulgaonkar A, Liu X, Harrington SM, Guo J, Xin Y, Xiong Y, Nham K, Silvers W, Hao G, Sun X, Chen M, Hannan R, Qiao J, Dong H, Peng H, Fu YX J. Clin. Invest. 2018 Feb 128 2 580-588

An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents.

Zhang F, Hao G, Shao M, Nham K, An Y, Wang Q, Zhu Y, Kusminski CM, Hassan G, Gupta RK, Zhai Q, Sun X, Scherer PE, Oz OK Cell Metab. 2018 Jan 27 1 252-262.e3

Targeting Renal Cell Carcinoma with a HIF-2 antagonist.

Chen W, Hill H, Christie A, Kim MS, Holloman E, Pavia-Jimenez A, Homayoun F, Ma Y, Patel N, Yell P, Hao G, Yousuf Q, Joyce A, Pedrosa I, Geiger H, Zhang H, Chang J, Gardner KH, Bruick RK, Reeves C, Hwang TH, Courtney K, Frenkel E, Sun X, Zojwalla N, Wong T, Rizzi JP, Wallace EM, Josey JA, Xie Y, Xie XJ, Kapur P, McKay RM, Brugarolas J Nature 2016 Sep

Design of a Small-Molecule Drug Conjugate for Prostate Cancer Targeted Theranostics.

Kumar A, Mastren T, Wang B, Hsieh JT, Hao G, Sun X Bioconjug. Chem. 2016 Jun

[(68) Ga]-HP-DO3A-nitroimidazole: a promising agent for PET detection of tumor hypoxia.

Wu Y, Hao G, Ramezani S, Saha D, Zhao D, Sun X, Sherry AD Contrast Media Mol Imaging 2015 Jun

Click-Chemistry Strategy for Labeling Antibodies with Copper-64 via a Cross-Bridged Tetraazamacrocyclic Chelator Scaffold.

Kumar A, Hao G, Liu L, Ramezani S, Hsieh JT, Öz OK, Sun X Bioconjug. Chem. 2015 Mar

Renal Clearance and Degradation of Glutathione-Coated Copper Nanoparticles.

Yang S, Sun S, Zhou C, Hao G, Liu J, Ramezani S, Yu M, Sun X, Zheng J Bioconjug. Chem. 2015 Feb

A comparative study of trans- and cis-isomers of a bone-seeking agent, DO2A2P.

Hao G, Liu W, Hassan G, Öz OK, Kovacs Z, Sun X Bioorg. Med. Chem. Lett. 2015 Feb 25 3 571-4

A Molecular Platform for Design and Synthesis of Targeted Dual-modality Imaging Probes.

Kumar A, Zhang S, Hao G, Hassan G, Ramezani S, Lo ST, Sagiyama K, Takahashi M, Sherry AD, Oz OK, Kovács Z, Sun X Bioconjug. Chem. 2015 Jan

Tumor-specific targeting by Bavituximab, a phosphatidylserine-targeting monoclonal antibody with vascular targeting and immune modulating properties, in lung cancer xenografts.

Gerber DE, Hao G, Watkins L, Stafford JH, Anderson J, Holbein B, Öz OK, Mathews D, Thorpe PE, Hassan G, Kumar A, Brekken RA, Sun X Am J Nucl Med Mol Imaging 2015 5 5 493-503

• Fall 2009 North and Central Texas Clinical and Translational Science Initiative (NCTCTSI) Pilot Grant Award
  (2009)
• Young Researcher Award, the Third International Workshop on Biomedical Imaging
  Fukui, Japan (2004)

• Society of Radiopharmaceutical Sciences (2010)
• The American Chemical Society (2010)
• The Society of Nuclear Medicine (2009)