Biography

Dr. Zhang joined UT Southwestern as an assistant professor in September, 2007. He previously was a postdoctoral fellow at the University of Texas M.D. Anderson Cancer Center.

Dr. Zhang’s research interest in statistical methodology lies in two main areas: Bayesian hierarchical modeling and clinical trial design. He has published multiple papers on the application of Bayesian hierarchical models to disease mapping, joint modeling of longitudinal and survival outcomes, item-response theory for grant review, functional enrichment analysis to detect important pathways, and multi-level modeling to detect factors that impact cancer screening, etc. Another area of his research interest is design methodology for clinical trials to account for various pragmatic issues such as correlated outcomes (clustered and longitudinal), missing data, small sample sizes, historical control, random variability in cluster size, and cost constraints, etc. He has published multiple high quality papers in this area and in 2015 he co-authored a book titled “Sample Size Calculations on Clustered and Longitudinal Outcomes in Clinical Research” (Chapman & Hall, New York). Dr. Zhang has been successful in securing extramural grants as the PI to support his independent research program: an NIH R03 grant to conduct secondary data analysis on VA HIV registry in 2012; an NSF grant to build risk prediction model based on electronic health record data in 2013; and a PCORI methodology development grant to address pragmatic design issues in stepped-wedge cluster randomized trials in 2017.

Education

Graduate School
Xiamen University - China , Econometrics
Graduate School
University of Missouri-Columbi (2005), Statistics

Research Interest

  • Bayesian statistical methods
  • Bioinformatics
  • Clinical trial design
  • Missing data methods
  • Multi-level models

Publications

Featured Publications LegendFeatured Publications

Long-Term Outcomes of Short-Term Statin Use in Healthy Adults: A Retrospective Cohort Study.
Mansi IA, English J, Zhang S, Mortensen EM, Halm EA Drug Saf 2016 Mar
Predicting all-cause readmissions using electronic health record data from the entire hospitalization: Model development and comparison.
Nguyen OK, Makam AN, Clark C, Zhang S, Xie B, Velasco F, Amarasingham R, Halm EA J Hosp Med 2016 Feb
Genetic changes found in a distinct clade of Enterovirus D68 associated with paralysis during the 2014 outbreak.
Zhang Y, Cao J, Zhang S, Lee AJ, Sun G, Larsen CN, Zhao H, Gu Z, He S, Klem EB, Scheuermann RH Virus Evol 2016 Jan 2 1 vew015
Mechanisms of bone disease in HIV and hepatitis C virus: impact of bone turnover, tenofovir exposure, sex steroids and severity of liver disease.
Bedimo R, Cutrell J, Zhang S, Drechsler H, Gao A, Brown G, Farukhi I, Castanon R, Tebas P, Maalouf NN AIDS 2015 Nov
Sample size considerations for split-mouth design.
Zhu H, Zhang S, Ahn C Stat Methods Med Res 2015 Aug
Long-term changes in quality of life after endoscopic resection of sinonasal and skull-base tumors.
Derousseau T, Manjunath L, Harrow B, Zhang S, Batra PS Int Forum Allergy Rhinol 2015 Aug
Sample size considerations for historical control studies with survival outcomes.
Zhu H, Zhang S, Ahn C J Biopharm Stat 2015 Jun
Induction Therapies in Live Donor Kidney Transplantation on Tacrolimus and Mycophenolate With or Without Steroid Maintenance.
Tanriover B, Zhang S, MacConmara M, Gao A, Sandikci B, Ayvaci MU, Mete M, Tsapepas D, Rajora N, Mohan P, Lakhia R, Lu CY, Vazquez M Clin J Am Soc Nephrol 2015 Jun 10 6 1041-9
Acinetobacter infections and outcomes at an academic medical center: a disease of long-term care.
Townsend J, Park AN, Gander R, Orr K, Arocha D, Zhang S, Greenberg DE Open Forum Infect Dis 2015 Jan 2 1 ofv023
A subset of CD163(+) macrophages displays mixed polarizations in discoid lupus skin.
Chong BF, Tseng LC, Hosler GA, Teske NM, Zhang S, Karp DR, Olsen NJ, Mohan C Arthritis Res. Ther. 2015 17 1 324

Books

Featured Books Legend Featured Books

Honors & Awards

  • Early Career Researcher and Postgraduate travel awards
    International Society for Bayesian Analysis (2008)
  • Graduate Professional Council Travel Scholarship
    University of Missouri-Columbia (2004)
  • Outstanding Performance in Doctoral Exams
    Department of Statistics, University of Missouri-Columbia (2003)
  • Excellent Student Award
    Xiamen University, China (1999)
  • Third Prize
    College Student Science and Technology Thesis Competition, Fujian, China (1998)

Professional Associations/Affiliations

  • Eastern North American Region (ENAR) of the International Biometric Society (IBS)
  • Institute of Mathematical Statistics
  • The American Statistical Association