Biography

Dr. Zhang joined UT Southwestern as an assistant professor in September, 2007. He previously was a postdoctoral fellow at the University of Texas M.D. Anderson Cancer Center.

Dr. Zhang’s research interest in statistical methodology lies in two main areas: Bayesian hierarchical modeling and clinical trial design. He has published multiple papers on the application of Bayesian hierarchical models to disease mapping, joint modeling of longitudinal and survival outcomes, item-response theory for grant review, functional enrichment analysis to detect important pathways, and multi-level modeling to detect factors that impact cancer screening, etc. Another area of his research interest is design methodology for clinical trials to account for various pragmatic issues such as correlated outcomes (clustered and longitudinal), missing data, small sample sizes, historical control, random variability in cluster size, and cost constraints, etc. He has published multiple high quality papers in this area and in 2015 he co-authored a book titled “Sample Size Calculations on Clustered and Longitudinal Outcomes in Clinical Research” (Chapman & Hall, New York). Dr. Zhang has been successful in securing extramural grants as the PI to support his independent research program: an NIH R03 grant to conduct secondary data analysis on VA HIV registry in 2012; an NSF grant to build risk prediction model based on electronic health record data in 2013; and a PCORI methodology development grant to address pragmatic design issues in stepped-wedge cluster randomized trials in 2017.

Education

Graduate School
Xiamen University - China , Econometrics
Graduate School
University of Missouri-Columbi (2005), Statistics

Research Interest

  • Bayesian statistical methods
  • Bioinformatics
  • Clinical trial design
  • Missing data methods
  • Multi-level models

Publications

Featured Publications LegendFeatured Publications

Association of Clinician Behaviors and Weight Change in School-Aged Children.
Turer CB, Barlow SE, Sarwer DB, Adamson B, Sanders J, Ahn C, Zhang S, Flores G, Skinner CS, Am J Prev Med 2019 Sep 57 3 384-393
Pediatric heterozygous familial hypercholesterolemia patients have locally increased aortic pulse wave velocity and wall thickness at the aortic root.
Tran A, Burkhardt B, Tandon A, Blumenschein S, van Engelen A, Cecelja M, Zhang S, Uribe S, Mura J, Greil G, Hussain T, Int J Cardiovasc Imaging 2019 Jun
Clinical and Sociobehavioral Prediction Model of 30-Day Hospital Readmissions Among People With HIV and Substance Use Disorder: Beyond Electronic Health Record Data.
Nijhawan AE, Metsch LR, Zhang S, Feaster DJ, Gooden L, Jain MK, Walker R, Huffaker S, Mugavero MJ, Jacobs P, Armstrong WS, Daar ES, Sullivan M, Del Rio C, Halm EA J. Acquir. Immune Defic. Syndr. 2019 Mar 80 3 330-341
Identifying Additional Risk Factors for Thrombosis and Pregnancy Morbidities Among Antiphospholipid Antibodies Carriers.
Zuo Y, Fan J, Sarode R, Zhang S, Makris UE, Karp DR, Shen YM Clin. Appl. Thromb. Hemost. 2018 Sep 24 6 980-985

Books

Featured Books Legend Featured Books

Honors & Awards

  • Early Career Researcher and Postgraduate travel awards
    International Society for Bayesian Analysis (2008)
  • Graduate Professional Council Travel Scholarship
    University of Missouri-Columbia (2004)
  • Outstanding Performance in Doctoral Exams
    Department of Statistics, University of Missouri-Columbia (2003)
  • Excellent Student Award
    Xiamen University, China (1999)
  • Third Prize
    College Student Science and Technology Thesis Competition, Fujian, China (1998)

Professional Associations/Affiliations

  • Eastern North American Region (ENAR) of the International Biometric Society (IBS)
  • Institute of Mathematical Statistics
  • The American Statistical Association