Xuewu Zhang, Ph.D. Professor Endowed Title Virginia Murchison Linthicum Scholar in Medical Research School Medical School Department Pharmacology | Biophysics Graduate Programs Molecular Biophysics Education Undergraduate Wuhan University (1995), Biology Graduate School Yeshiva Uni - Bronx Campus (2003), Cell Biology Research Interest Signal transduction Structural biology Publications Featured Publications Activation of human STING by a molecular glue-like compound. Li J, Canham SM, Wu H, Henault M, Chen L, Liu G, Chen Y, Yu G, Miller HR, Hornak V, Brittain SM, Michaud GA, Tutter A, Broom W, Digan ME, McWhirter SM, Sivick KE, Pham HT, Chen CH, Tria GS, McKenna JM, Schirle M, Mao X, Nicholson TB, Wang Y, Jenkins JL, Jain RK, Tallarico JA, Patel SJ, Zheng L, Ross NT, Cho CY, Zhang X, Bai XC, Feng Y, Nat Chem Biol 2023 Oct Structural basis of insulin fibrillation. Wang L, Hall CE, Uchikawa E, Chen D, Choi E, Zhang X, Bai XC, Sci Adv 2023 Sep 9 37 eadi1057 Inhibition of FAM46/TENT5 activity by BCCIPα adopting a unique fold. Liu S, Chen H, Yin Y, Lu D, Gao G, Li J, Bai XC, Zhang X, Sci Adv 2023 Apr 9 14 eadf5583 Mechanism of regulation of the Helicobacter pylori Cagβ ATPase by CagZ. Wu X, Zhao Y, Zhang H, Yang W, Yang J, Sun L, Jiang M, Wang Q, Wang Q, Ye X, Zhang X, Wu Y, Nat Commun 2023 Jan 14 1 479 Novel Bcl-2 Inhibitors Selectively Disrupt the Autophagy-Specific Bcl-2-Beclin 1 Protein-Protein Interaction. Dong X, Liang Q, Pan YZ, Wang X, Kuo YC, Chiang WC, Zhang X, Williams NS, Rizo J, Levine B, De Brabander JK, ACS Med Chem Lett 2022 Sep 13 9 1510-1516 SNARE assembly enlightened by cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex. Stepien KP, Xu J, Zhang X, Bai XC, Rizo J, Sci Adv 2022 Jun 8 25 eabo5272 Cryo-electron Microscopic Analysis of Single-Pass Transmembrane Receptors. Cai K, Zhang X, Bai XC, Chem Rev 2022 Jun Synergistic activation of the insulin receptor via two distinct sites. Li J, Park J, Mayer JP, Webb KJ, Uchikawa E, Wu J, Liu S, Zhang X, Stowell MHB, Choi E, Bai XC, Nat Struct Mol Biol 2022 Apr 29 4 357-368 Activation of STING by targeting a pocket in the transmembrane domain. Lu D, Shang G, Li J, Lu Y, Bai XC, Zhang X, Nature 2022 04 604 7906 557-562 Python-based Helix Indexer: A graphical user interface program for finding symmetry of helical assembly through Fourier-Bessel indexing of electron microscopic data. Zhang X, Protein Sci 2022 01 31 1 107-117 Results 1-10 of 52 1 2 3 4 5 Next Last Honors & Awards Virginia Murchison Linthicum Scholar in Medical ResearchUT Southwestern Medical Center (2007) Julius Marmur Research AwardAlbert Einstein School of Medicine (2002)
