Xuewu Zhang, Ph.D. Titles and Appointments Professor Endowed Title Virginia Murchison Linthicum Scholar in Medical Research School Medical School Department Pharmacology | Biophysics Graduate Programs Molecular Biophysics Education Undergraduate Wuhan University (1995), Biology Graduate School Yeshiva Uni - Bronx Campus (2003), Cell Biology Research Interest Signal transduction Structural biology Publications Featured Publications Mouse radial spoke 3 is a metabolic and regulatory hub in cilia. Zhao Y, Song K, Tavakoli A, Gui L, Fernandez-Gonzalez A, Zhang S, Dzeja PP, Mitsialis SA, Zhang X, Nicastro D, Nat Struct Mol Biol 2025 Jun LILRB3 genetic variation is associated with kidney transplant failure in African American recipients. Sun Z, Yi Z, Wei C, Wang W, Ren T, Cravedi P, Tedla F, Ward SC, Azeloglu E, Schrider DR, Li Y, Khan A, Zanoni F, Fu J, Ali S, Liu S, Liang D, Liu T, Li H, Xi C, Vy TH, Mosoyan G, Sun Q, Kumar A, Zhang Z, Farouk S, Campell K, Ochando J, Lee K, Coca S, Xiang J, Connolly P, Gallon L, O'Connell PJ, Colvin R, Menon MC, Nadkarni G, He JC, Kraft M, Jiang X, Zhang X, Kiryluk K, Cherukuri A, Lakkis FG, Zhang W, Chen SH, Heeger PS, Zhang W, Nat Med 2025 Mar Helical reconstruction of VP39 reveals principles for baculovirus nucleocapsid assembly. Benning FMC, Jenni S, Garcia CY, Nguyen TH, Zhang X, Chao LH, Nat Commun 2024 Jan 15 1 250 Applications of cryo-EM in drug development for STING. Bai XC, Zhang X, Curr Opin Struct Biol 2024 Jan 84 102767 Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma. Hu L, Zhang Y, Guo L, Zhong H, Xie L, Zhou J, Liao C, Yao H, Fang J, Liu H, Zhang C, Zhang H, Zhu X, Luo M, von Kriegsheim A, Li B, Luo W, Zhang X, Chen X, Mendell JT, Xu L, Kapur P, Baldwin AS, Brugarolas J, Zhang Q, Mol Cell 2024 Jan Activation of human STING by a molecular glue-like compound. Li J, Canham SM, Wu H, Henault M, Chen L, Liu G, Chen Y, Yu G, Miller HR, Hornak V, Brittain SM, Michaud GA, Tutter A, Broom W, Digan ME, McWhirter SM, Sivick KE, Pham HT, Chen CH, Tria GS, McKenna JM, Schirle M, Mao X, Nicholson TB, Wang Y, Jenkins JL, Jain RK, Tallarico JA, Patel SJ, Zheng L, Ross NT, Cho CY, Zhang X, Bai XC, Feng Y, Nat Chem Biol 2023 Oct Structural basis of insulin fibrillation. Wang L, Hall CE, Uchikawa E, Chen D, Choi E, Zhang X, Bai XC, Sci Adv 2023 Sep 9 37 eadi1057 Inhibition of FAM46/TENT5 activity by BCCIPα adopting a unique fold. Liu S, Chen H, Yin Y, Lu D, Gao G, Li J, Bai XC, Zhang X, Sci Adv 2023 Apr 9 14 eadf5583 Mechanism of regulation of the Helicobacter pylori Cagβ ATPase by CagZ. Wu X, Zhao Y, Zhang H, Yang W, Yang J, Sun L, Jiang M, Wang Q, Wang Q, Ye X, Zhang X, Wu Y, Nat Commun 2023 Jan 14 1 479 Novel Bcl-2 Inhibitors Selectively Disrupt the Autophagy-Specific Bcl-2-Beclin 1 Protein-Protein Interaction. Dong X, Liang Q, Pan YZ, Wang X, Kuo YC, Chiang WC, Zhang X, Williams NS, Rizo J, Levine B, De Brabander JK, ACS Med Chem Lett 2022 Sep 13 9 1510-1516 Results 1-10 of 57 1 2 3 4 5 Next Last Honors & Awards Virginia Murchison Linthicum Scholar in Medical ResearchUT Southwestern Medical Center (2007) Julius Marmur Research AwardAlbert Einstein School of Medicine (2002)
