
Nicholas Conrad, Ph.D.
Professor
Endowed Title Southwestern Medical Foundation Scholar in Biomedical Research
Department Microbiology
Graduate Programs Biological Chemistry, Molecular Microbiology
Education
- Graduate School
- Johns Hopkins University (2002), Biochemistry
Research Interest
- Intron Retention
- KSHV gene expression
- RNA decay
- RNA methylation
Publications
Featured Publications
- SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A.
- Scarborough AM, Flaherty JN, Hunter OV, Liu K, Kumar A, Xing C, Tu BP, Conrad NK, Elife 2021 May 10
- Kaposi's Sarcoma-Associated Herpesvirus Fine-Tunes the Temporal Expression of Late Genes by Manipulating a Host RNA Quality Control Pathway.
- Ruiz JC, Devlin AM, Kim J, Conrad NK, J Virol 2020 07 94 14
- Kaposi's sarcoma-associated herpesvirus ORF57 protein protects viral transcripts from specific nuclear RNA decay pathways by preventing hMTR4 recruitment.
- Ruiz JC, Hunter OV, Conrad NK, PLoS Pathog. 2019 02 15 2 e1007596
- Balance between MAT2A intron detention and splicing is determined co-transcriptionally.
- Pendleton KE, Park SK, Hunter OV, Bresson SM, Conrad NK RNA 2018 Mar
- A Conserved Splicing Silencer Dynamically Regulates O-GlcNAc Transferase Intron Retention and O-GlcNAc Homeostasis.
- Park SK, Zhou X, Pendleton KE, Hunter OV, Kohler JJ, O'Donnell KA, Conrad NK Cell Rep 2017 Aug 20 5 1088-1099
- The U6 snRNA m(6)A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention.
- Pendleton KE, Chen B, Liu K, Hunter OV, Xie Y, Tu BP, Conrad NK Cell 2017 May 169 5 824-835.e14
- Canonical Poly(A) Polymerase Activity Promotes the Decay of a Wide Variety of Mammalian Nuclear RNAs.
- Bresson SM, Hunter OV, Hunter AC, Conrad NK PLoS Genet. 2015 Oct 11 10 e1005610
- New insights into the expression and functions of the Kaposi's sarcoma-associated herpesvirus long noncoding PAN RNA.
- Conrad NK Virus Res. 2015 Jun
- HITS-CLIP analysis uncovers a link between the Kaposi's sarcoma-associated herpesvirus ORF57 protein and host pre-mRNA metabolism.
- Sei E, Wang T, Hunter OV, Xie Y, Conrad NK PLoS Pathog. 2015 Feb 11 2 e1004652
- Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy.
- Stubbs SH, Conrad NK Nucleic Acids Res. 2015 Jan 43 1 504-19