Dr. Dong is originally from China and received his Ph.D in Biology from Tsinghua University, Beijing, China. Dr. Dong brings to UTSW a strong background in innate immunity and virology. He currently specializes in unraveling the molecular mechanisms of host-pathogens interaction, particularly the role of autophagy in innate immunity against intracellular pathogens. Dr. Dong’s interests outside of medicine include his family, reading, history and arts.


Tsinghua University (2000)
Graduate School
Tsinghua University (2005)

Research Interest

  • Autophagy in Innate Immunity against Intracellular Pathogens
  • Host-Pathogen Interactions


Featured Publications LegendFeatured Publications

Murine Gamma Herpesvirus 68 Hijacks MAVS and IKKß to Abrogate NF?B Activation and Antiviral Cytokine Production.
Dong X, Feng P PLoS Pathog. 2011 Nov 7 11 e1002336
Murine ?-herpesvirus 68 Evades Host Cytokine Production via RTA-induced RelA Degradation.
Dong X, He Z, Durakoglugil D, Arneson L, Shen Y, Feng P Journal of virology 2011 Nov
Dissecting Host-virus Interaction in Lytic Replication of a Model Herpesvirus.
Dong X, Feng P J Vis Exp 2011 56
Murine gamma-herpesvirus 68 hijacks MAVS and IKKbeta to initiate lytic replication.
Dong X, Feng H, Sun Q, Li H, Wu TT, Sun R, Tibbetts SA, Chen ZJ, Feng P PLoS Pathog. 2010 6 7 e1001001
Kaposi's sarcoma-associated herpesvirus K7 induces viral G protein-coupled receptor degradation and reduces its tumorigenicity.
Feng H, Dong X, Negaard A, Feng P PLoS Pathog. 2008 4 9 e1000157