Dr. Dong is originally from China and received his Ph.D in Biology from Tsinghua University, Beijing, China. Dr. Dong brings to UTSW a strong background in innate immunity and virology. He currently specializes in unraveling the molecular mechanisms of host-pathogens interaction, particularly the role of autophagy in innate immunity against intracellular pathogens. Dr. Dong’s interests outside of medicine include his family, reading, history and arts.

Research Interest

  • Autophagy in Innate Immunity against Intracellular Pathogens
  • Host-Pathogen Interactions


Featured Publications LegendFeatured Publications

Murine Gamma Herpesvirus 68 Hijacks MAVS and IKKß to Abrogate NF?B Activation and Antiviral Cytokine Production.
Dong X, Feng P PLoS Pathog. 2011 Nov 7 11 e1002336
Murine ?-herpesvirus 68 Evades Host Cytokine Production via RTA-induced RelA Degradation.
Dong X, He Z, Durakoglugil D, Arneson L, Shen Y, Feng P Journal of virology 2011 Nov
Dissecting Host-virus Interaction in Lytic Replication of a Model Herpesvirus.
Dong X, Feng P J Vis Exp 2011 56
Murine gamma-herpesvirus 68 hijacks MAVS and IKKbeta to initiate lytic replication.
Dong X, Feng H, Sun Q, Li H, Wu TT, Sun R, Tibbetts SA, Chen ZJ, Feng P PLoS Pathog. 2010 6 7 e1001001
Kaposi's sarcoma-associated herpesvirus K7 induces viral G protein-coupled receptor degradation and reduces its tumorigenicity.
Feng H, Dong X, Negaard A, Feng P PLoS Pathog. 2008 4 9 e1000157