Chengcheng Zhang, Ph.D.

Professor

Endowed Title: Hortense L. and Morton H. Sanger Professorship in Oncology; Michael L. Rosenberg Scholar in Medical Research
School: Medical School
Department: Physiology
Graduate Programs: Cancer Biology, Immunology

Education

Undergraduate: Univ of Science & Tech China , Molecular & Cell Biology
Graduate School: Chinese Academy of Sciences-Sh (1995), Biotechnology
Graduate School: Univ of Illinois @ Urbana-Cham (1999), Biochemistry

Research Interest

Publications

Featured Publications

Hypoxia fate-mapping identifies cycling cardiomyocytes in the adult heart: Kimura W, Xiao F, Canseco DC, Muralidhar S, Thet S, Zhang HM, Abderrahman Y, Chen R, Garcia JA, Shelton JM, Richardson JA, Ashour AM, Asaithamby A, Liang H, Xing C, Lu Z, Zhang CC, Sadek HA. Nature 2015 7559 523 226-230
Hypoxia and Metabolic Properties of Hematopoietic Stem Cells. Antioxidants & Redox Signaling: Zhang CC, Sadek H. Antioxidants & Redox Signaling. 2014 12 20 epub
Profilin-1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrow.: Zheng J, Lu Z, Kocabas F, Bottcher RT, Costell M, Kang X, Liu X, DeBerardinis RJ, Wang Q, Chen G, Sadek H*, Zhang CC*. Blood 2014 123 992-1001
Novel signaling axis in CML-initiating cells.: Zhang CC Blood 2014 16 123
A motif in LILRB2 critical for Angptl2 binding and activation: Deng M*, Lu Z*, Zheng J, Wan X, Chen X, Hirayasu K, Sun H, Lam Y, Chen L, Wang Q, Song C, Huang N, Gao GF, Jiang Y, Arase H, Zhang CC. Blood 2014 epub
Meis1 regulates the metabolic phenotype and oxidative defense of hematopoietic stem cells.: Kocabas F, Zheng J, Thet S, Copeland NG, Jenkins NA, DeBerardinis RJ, Zhang CC*, Sadek HA*. Blood 2012 25 120 4963-72
Angiopoietin-like protein 3 supports the activity of mouse hematopoietic stem cells in the bone marrow niche: Zheng J, Huynh H, Umikawa M, Silvany R, Zhang CC Blood 2011 117 470-479
IGF Binding Protein 2 Supports the Survival and Cycling of Hematopoietic Stem Cells: Huynh H, Zheng J, Umikawa M, Zhang C, Silvany R, Iizuka S, Holzenberger M, Zhang W, Zhang CC Blood 2011 118
IGFBP2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells: Huynh H, Iizuka S, Kaba M, Kirak O, Zheng J, Lodish HF, Zhang CC Stem Cells 2008 26 1628-1635

Honors & Awards

Hortense L. and Morton H. Sanger Professorship in Oncology
(2015)
Leukemia & Lymphoma Society Scholar Award
(2013)
Royan International Research Award
(2012)
Gabrielle’s Angel Foundation for Cancer Research Fellow
(2009)
Basil O’Connor Scholar, March of Dimes Foundation
(2008)
American Society of Hematology Junior Faculty Scholar
(2007)
Howard Temin KO1 Award, National Cancer Institute
(2006)
Michael L. Rosenberg Scholar in Biomedical Research, UT Southwestern Medical Center
(2006)

Professional Associations/Affiliations