Download Curriculum Vitae

Dr. Williams received his A.S. degree from Collin County Community College in 1997.  Dr. Williams subsequently received his B.S. degree in the study of Biology from the University of Texas at Dallas in 1999. In 2006, he completed his Ph.D. in Neuroscience from Tulane University in New Orleans, where he worked with Dr. Bret N. Smith (currently at the University of Kentucky). He joined the Division of Hypothalamic Research in the Department of Internal Medicine here at UT Southwestern, following completion of his postdoctoral studies with Dr. Joel K. Elmquist.  His lab uses mouse genetics, electrophysiology, and systems neuroscience approaches to study the cellular mechanisms within the brain which may underlie the coordinated control of food intake, body weight, and glucose homeostasis.


University of Texas at Dallas (1999), Biology
Graduate School
Tulane University of Louisiana (2006), Cognition and Neuroscience

Research Interest

  • Central Autonomic Control
  • Diabetes and Glucose Homeostasis
  • Electrophysiology
  • Neurophysiology
  • Obesity and Body Weight Homeostasis
  • Synaptic Transmission


Featured Publications LegendFeatured Publications

Brain SIRT1: anatomical distribution and regulation by energy availability.
Ramadori G, Lee CE, Bookout AL, Lee S, Williams KW, Anderson J, Elmquist JK, Coppari R J. Neurosci. 2008 Oct 28 40 9989-96
Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice.
Hill JW, Williams KW, Ye C, Luo J, Balthasar N, Coppari R, Cowley MA, Cantley LC, Lowell BB, Elmquist JK J. Clin. Invest. 2008 May 118 5 1796-805
"AMPing up" our understanding of the hypothalamic control of energy balance.
Williams KW, Coppari R, Elmquist JK J. Clin. Invest. 2007 Aug 117 8 2089-92
Rapid inhibition of neurons in the dorsal motor nucleus of the vagus by leptin.
Williams KW, Zsombok A, Smith BN Endocrinology 2007 Apr 148 4 1868-81
Rapid inhibition of neural excitability in the nucleus tractus solitarii by leptin: implications for ingestive behaviour.
Williams KW, Smith BN J. Physiol. (Lond.) 2006 Jun 573 Pt 2 395-412
Excitatory and inhibitory local circuit input to the rat dorsal motor nucleus of the vagus originating from the nucleus tractus solitarius.
Davis SF, Derbenev AV, Williams KW, Glatzer NR, Smith BN Brain Res. 2004 Aug 1017 1-2 208-17
Selective enhancement of synaptic inhibition by hypocretin (orexin) in rat vagal motor neurons: implications for autonomic regulation.
Davis SF, Williams KW, Xu W, Glatzer NR, Smith BN J. Neurosci. 2003 May 23 9 3844-54

Honors & Awards

  • Mentored Research Scientist Development Award
    NIH-NIDDK (087780) (2010)
  • Post-Doctoral Ruth L. Kirschstein National Research Service Award
    NIH-NIDDK (DK077487) (2006)
  • Senior Vice President's award for excellence in research and presentation by a graduate student
    Tulane University - research days (2004)
  • B.S. awarded with cum laude
    The University of Texas at Dallas (1999)
  • A.S. awarded with magna cum laude
    Collin County Community College (1997)
  • UTD Redman scholars program recipient
    Redman Foundation Scholarship (1997)

Professional Associations/Affiliations

  • The Endocrine Society (2011)
  • The Society for Neuroscience (2002)