Peter Sguigna, M.D.

Dr. Peter Sguigna received a bachelor of science degree in biomedical engineering as well as a minor in Mathematics from Texas A&M University, and completed his advanced degrees in medicine, neurology, as well as multiple sclerosis and neuroimmunology from the University of Texas Southwestern. In March of 2020 he was recruited to stay at the University of Texas Southwestern to lead its neuro-ophthalmology initiative within the Department of Neurology. He sees patients with multiple sclerosis, optic neuritis, and other neuro-immunological disorders.

Dr. Sguigna's research interests and activities include advanced diagnostic imaging of neuro-ophthalmological disorders, as well as unraveling the neuro-retinal circuitry in neuroimmunological diseases. He actively works on better ways to distinguish these disorders using non-invasive technology. He uses specialized testing to gain insight into some of the most disabling symptoms for patients with multiple sclerosis. Lastly, he coordinates for clinical trials for better treatment of patients with multiple sclerosis.

Medical School

UT Southwestern Medical School (2014)

Residency

UT Southwestern Medical Center (2018), Neurology

Fellowship

UT Southwestern Medical Center (2020), Multiple Sclerosis

• Clinical Treatment Trials
• Medical Devices
• MOG Antibody Associated Disorders
• Multiple Sclerosis
• Neuro-Ophthalmology
• Neuromyelitis Optica Spectrum Disorder
• Optic Neuritis
• Visual Dysfunction

Featured Publications

Asymptomatic retinal vasculopathy in neuropsychiatric systemic lupus erythematosus.

Sguigna PV, Tardo L, Conger D, Hogan R, Greenberg BM, J Neurol Sci 2021 Aug 430 118053

Utilization of Visual Acuity Retroilluminated Charts for the Assessment of Afferent Visual System Dysfunction in a Pediatric Neuroimmunology Population.

Sguigna PV, McCreary MC, Conger DL, Graves JS, Benson LA, Waldman AT, Greenberg BM, J Neuroophthalmol 2020 Aug

Cataclysmically disseminating neurologic presentation in an immunosuppressed lupus patient: From the National Multiple Sclerosis Society Case Conference Proceedings.

Perrone CM, Lisak RP, Meltzer EI, Sguigna P, Tizazu E, Jacobs D, Melamed E, Lucas A, Freeman L, Pardo G, Goodman A, Fox EJ, Costello K, Parsons MS, Zamvil SS, Frohman EM, Frohman TC, Neurol Neuroimmunol Neuroinflamm 2019 07 6 4 e582

Atypical Anti-MOG syndrome with aseptic meningoencephalitis and pseudotumor cerebri-like presentations.

Narayan RN, Wang C, Sguigna P, Husari K, Greenberg B Mult Scler Relat Disord 2018 Oct 27 30-33

Retinal Architecture and Melanopsin-Mediated Pupillary Response Characteristics: A Putative Pathophysiologic Signature for the Retino-Hypothalamic Tract in Multiple Sclerosis.

Meltzer E, Sguigna PV, Subei A, Beh S, Kildebeck E, Conger D, Conger A, Lucero M, Frohman BS, Frohman AN, Saidha S, Galetta S, Calabresi PA, Rennaker R, Frohman TC, Kardon RH, Balcer LJ, Frohman EM JAMA Neurol 2017 05 74 5 574-582

Managing Disability in Progressive Multiple Sclerosis.

Dubey D, Sguigna P, Stüve O Curr Treat Options Neurol 2016 Jun 18 6 27

Subclinical optic neuritis in pediatric myelin oligodendrocyte glycoprotein antibody-associated disease.

Nguyen L, Wang CX, Conger DL, Sguigna PV, Singh S, Greenberg BM, Mult Scler Relat Disord 2023 Jun 76 104802

Disease associations of excessive daytime sleepiness in multiple sclerosis: A prospective study.

Sguigna PV, Toranian S, Tardo LM, Blackburn KM, Horton LA, Conger D, Meltzer E, Hogan RN, McCreary MC, Zee PC, Takahashi JS, Greenberg BM, Mult Scler J Exp Transl Clin 2023 9 1 20552173231159560

A cross-sectional natural history study of aspartylglucosaminuria.

Goodspeed K, Horton D, Lowden A, Sguigna PV, Booth T, Wang ZJ, Edgar VB, JIMD Rep 2022 Sep 63 5 425-433

Application of the International Interocular Difference Thresholds into Practice: Localising the Patient Experience.

Sguigna PV, Tardo LM, Blackburn KM, Horton LA, Conger DL, Hogan RN, McCreary MC, Greenberg BM, Neuroophthalmology 2022 46 6 375-382