Dr. Peter Sguigna received a bachelor of science degree in biomedical engineering as well as a minor in Mathematics from Texas A&M University, and completed his advanced degrees in medicine, neurology, as well as multiple sclerosis and neuroimmunology from the University of Texas Southwestern. In March of 2020 he was recruited to stay at the University of Texas Southwestern to lead its neuro-ophthalmology initiative within the Department of Neurology. He sees patients with multiple sclerosis, optic neuritis, and other neuro-immunological disorders.

Dr. Sguigna's research interests and activities include advanced diagnostic imaging of neuro-ophthalmological disorders, as well as unraveling the neuro-retinal circuitry in neuroimmunological diseases. He actively works on better ways to distinguish these disorders using non-invasive technology. He uses specialized testing to gain insight into some of the most disabling symptoms for patients with multiple sclerosis. Lastly, he coordinates for clinical trials for better treatment of patients with multiple sclerosis.


Medical School
UT Southwestern Medical School (2014)
UT Southwestern Medical Center (2018), Neurology
UT Southwestern Medical Center (2020), Multiple Sclerosis

Research Interest

  • Clinical Treatment Trials
  • Medical Devices
  • MOG Antibody Associated Disorders
  • Multiple Sclerosis
  • Neuro-Ophthalmology
  • Neuromyelitis Optica Spectrum Disorder
  • Optic Neuritis
  • Visual Dysfunction


Featured Publications LegendFeatured Publications

Subclinical optic neuritis in pediatric myelin oligodendrocyte glycoprotein antibody-associated disease.
Nguyen L, Wang CX, Conger DL, Sguigna PV, Singh S, Greenberg BM, Mult Scler Relat Disord 2023 Jun 76 104802
Disease associations of excessive daytime sleepiness in multiple sclerosis: A prospective study.
Sguigna PV, Toranian S, Tardo LM, Blackburn KM, Horton LA, Conger D, Meltzer E, Hogan RN, McCreary MC, Zee PC, Takahashi JS, Greenberg BM, Mult Scler J Exp Transl Clin 2023 9 1 20552173231159560
A cross-sectional natural history study of aspartylglucosaminuria.
Goodspeed K, Horton D, Lowden A, Sguigna PV, Booth T, Wang ZJ, Edgar VB, JIMD Rep 2022 Sep 63 5 425-433
Application of the International Interocular Difference Thresholds into Practice: Localising the Patient Experience.
Sguigna PV, Tardo LM, Blackburn KM, Horton LA, Conger DL, Hogan RN, McCreary MC, Greenberg BM, Neuroophthalmology 2022 46 6 375-382