Richard Voit, M.D., Ph.D. Assistant Professor Endowed Title Horchow Family Scholar in Pediatrics School Medical School Department Pediatrics | Children's Medical Center Research Institute at UT Southwestern | Harold C. Simmons Comprehensive Cancer Center You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Richard A. Voit, M.D., Ph.D., is an Assistant Professor of Pediatrics in the Division of Pediatric Hematology and Oncology and is an affiliated member of the Children's Research Institute and the Harold C. Simmons Comprehensive Cancer Center. He is an Attending Physician in the Gill Center for Cancer and Blood Disorders at Children’s Medical Center in Dallas. Dr. Voit received his B.S. in molecular biology from the University of Texas at Dallas where he was a Eugene McDermott Scholar and his M.D. and Ph.D. from UT Southwestern. He completed general pediatrics residency and pediatric hematology-oncology fellowship at Boston Children's Hospital and the Dana Farber Cancer Institute. He joined the faculty of UT Southwestern in 2024 as a CPRIT First-time Tenure-track Scholar and a Horchow Family Endowed Scholar in Pediatrics. The Voit lab focuses on essential factors that govern hematopoeitic stem cell maintenance and hematopoeitic lineage committment to better understand the transcriptional and translational regulation of hematopoiesis. These endeavors will lead to better, targeted therapies for acute myeloid leukemia and inform the next generation of gene therapy for inherited bone marrow failure syndromes. The lab is also supported by a K08 award from the National Cancer Institute and Young Investigator Awards from the Alex's Lemonade Stand Foundation and the Edward P. Evans Foundation. We are a trainee-centered, patient-focused team of physicians and scientists dedicated to improving the lives of children with blood disorders. Education Medical School UT Southwestern Medical School (2014) Residency Boston Children's Hospital (2017), Pediatrics Fellowship Boston Children's Hospital (2020), Pediatric Hematology/oncology Publications Featured Publications A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia. Voit RA, Tao L, Yu F, Cato LD, Cohen B, Fleming TJ, Antoszewski M, Liao X, Fiorini C, Nandakumar SK, Wahlster L, Teichert K, Regev A, Sankaran VG, Nat Immunol 2023 Jan 24 1 69-83 Gene therapy for congenital marrow failure syndromes - no longer grasping at straws? Voit RA, Corey SJ, Haematologica 2023 Nov 108 11 2880-2882 MECOM Deficiency: from Bone Marrow Failure to Impaired B-Cell Development. Voit RA, Sankaran VG, J Clin Immunol 2023 Aug 43 6 1052-1066 CD11c regulates neutrophil maturation. Hou L, Voit RA, Shibamura-Fujiogi M, Koutsogiannaki S, Li Y, Chen Y, Luo H, Sankaran VG, Yuki K, Blood Adv 2023 Apr 7 7 1312-1325 Multi-omics on our multitudes. Voit RA, Sankaran VG, Nat Genet 2022 Oct 54 10 1449-1450 Pathogenic BCL11A variants provide insights into the mechanisms of human fetal hemoglobin silencing. Shen Y, Li R, Teichert K, Montbleau KE, Verboon JM, Voit RA, Sankaran VG, PLoS Genet 2021 Oct 17 10 e1009835 A unified model of human hemoglobin switching through single-cell genome editing. Shen Y, Verboon JM, Zhang Y, Liu N, Kim YJ, Marglous S, Nandakumar SK, Voit RA, Fiorini C, Ejaz A, Basak A, Orkin SH, Xu J, Sankaran VG, Nat Commun 2021 Aug 12 1 4991 Familial thrombocytopenia due to a complex structural variant resulting in a WAC-ANKRD26 fusion transcript. Wahlster L, Verboon JM, Ludwig LS, Black SC, Luo W, Garg K, Voit RA, Collins RL, Garimella K, Costello M, Chao KR, Goodrich JK, DiTroia SP, O'Donnell-Luria A, Talkowski ME, Michelson AD, Cantor AB, Sankaran VG, J Exp Med 2021 Jun 218 6 CD11c regulates hematopoietic stem and progenitor cells under stress. Hou L, Voit RA, Sankaran VG, Springer TA, Yuki K, Blood Adv 2020 Dec 4 24 6086-6097 Sowing the Seeds of Clonal Hematopoiesis. Liggett LA, Voit RA, Sankaran VG, Cell Stem Cell 2020 Aug 27 2 195-197 Results 1-10 of 16 1 2 Next Last Honors & Awards American Society for Clinical Investigation Emerging Generation Awardee (2024) CPRIT First-time Tenure-track Investigator (2024) National Cancer Institute K08 Awardee (2024) Alex's Lemonade Stand Young Investigator (2023) Evans MDS Young Investigator (2023)
