Richard Voit, M.D., Ph.D. Titles and Appointments Assistant Professor Endowed Title Horchow Family Scholar in Pediatrics Schools Medical School | Graduate School Departments Pediatrics | Children's Medical Center Research Institute at UT Southwestern | Harold C. Simmons Comprehensive Cancer Center Graduate Programs Cancer Biology You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Richard A. Voit, M.D., Ph.D., is an Assistant Professor of Pediatrics in the Division of Pediatric Hematology and Oncology and is an affiliated member of the Children's Research Institute and the Harold C. Simmons Comprehensive Cancer Center. He is an Attending Physician in the Gill Center for Cancer and Blood Disorders at Children’s Medical Center in Dallas. Dr. Voit received his B.S. in molecular biology from the University of Texas at Dallas where he was a Eugene McDermott Scholar and his M.D. and Ph.D. from UT Southwestern. He completed general pediatrics residency and pediatric hematology-oncology fellowship at Boston Children's Hospital and the Dana Farber Cancer Institute. He joined the faculty of UT Southwestern in 2024 as a CPRIT First-time Tenure-track Scholar and a Horchow Family Endowed Scholar in Pediatrics. The Voit lab focuses on essential factors that govern hematopoeitic stem cell maintenance and hematopoeitic lineage committment to better understand the transcriptional and translational regulation of hematopoiesis. These endeavors will lead to better, targeted therapies for acute myeloid leukemia and inform the next generation of gene therapy for inherited bone marrow failure syndromes. The lab is also supported by a K08 award from the National Cancer Institute and Young Investigator Awards from the Alex's Lemonade Stand Foundation and the Edward P. Evans Foundation. We are a trainee-centered, patient-focused team of physicians and scientists dedicated to improving the lives of children with blood disorders. Education Medical School UT Southwestern Medical School (2014) Residency Boston Children's Hospital (2017), Pediatrics Fellowship Boston Children's Hospital (2020), Pediatric Hematology/oncology Publications CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias Fleming TJ, Antoszewski M, Lambo S, Gundry MC, Piussi R, Wahlster L, Shah S, Reed FE, Dong KD, Paulo JA, Gygi SP, Mimoso C, Goldman SR, Adelman K, Perry JA, Pikman Y, Stegmaier K, Barrachina MN, Machlus KR, Hovestadt V, Arruda A, Minden MD, Voit RA, Sankaran VG Blood 2025 Dec 146 3019-3035 Regulated GATA1 expression as a universal gene therapy for Diamond-Blackfan anemia Voit RA, Liao X, Caulier A, Antoszewski M, Cohen B, Armant M, Lu HY, Fleming TJ, Kamal E, Wahlster L, Roche AM, Everett JK, Petrichenko A, Huang MM, Clarke W, Myers KC, Forester C, Perez-Atayde A, Bushman FD, Pellin D, Shimamura A, Williams DA, Sankaran VG Cell Stem Cell 2025 Jan 32 38-52.e6 Gene therapy for congenital marrow failure syndromes – no longer grasping at straws? Voit RA, Corey SJ Haematologica 2023 Nov 108 2880-2882 MECOM Deficiency: from Bone Marrow Failure to Impaired B-Cell Development Voit RA, Sankaran VG Journal of Clinical Immunology 2023 Aug 43 1052-1066 CD11c regulates neutrophil maturation Hou L, Voit RA, Shibamura-Fujiogi M, Koutsogiannaki S, Li Y, Chen Y, Luo H, Sankaran VG, Yuki K Blood Advances 2023 Apr 7 1312-1325 A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia Voit RA, Tao L, Yu F, Cato LD, Cohen B, Fleming TJ, Antoszewski M, Liao X, Fiorini C, Nandakumar SK, Wahlster L, Teichert K, Regev A, Sankaran VG Nature immunology 2023 Jan 24 69-83 Multi-omics on our multitudes Voit RA, Sankaran VG Nature genetics 2022 Oct 54 1449-1450 A unified model of human hemoglobin switching through single-cell genome editing Shen Y, Verboon JM, Zhang Y, Liu N, Kim YJ, Marglous S, Nandakumar SK, Voit RA, Fiorini C, Ejaz A, Basak A, Orkin SH, Xu J, Sankaran VG Nature communications 2021 Dec 12 Pathogenic BCL11A variants provide insights into the mechanisms of human fetal hemoglobin silencing Shen Y, Li R, Teichert K, Montbleau KE, Verboon JM, Voit RA, Sankaran VG PLoS genetics 2021 Oct 17 Familial thrombocytopenia due to a complex structural variant resulting in a WAC-ANKRD26 fusion transcript Wahlster L, Verboon JM, Ludwig LS, Black SC, Luo W, Garg K, Voit RA, Collins RL, Garimella K, Costello M, Chao KR, Goodrich JK, DiTroia SP, O’Donnell-Luria A, Talkowski ME, Michelson AD, Cantor AB, Sankaran VG Journal of Experimental Medicine 2021 Apr 218 Results 1-10 of 19 1 2 Next Last Honors & Awards American Society for Clinical Investigation Emerging Generation Awardee (2024) CPRIT First-time Tenure-track Investigator (2024) National Cancer Institute K08 Awardee (2024) Alex's Lemonade Stand Young Investigator (2023) Evans MDS Young Investigator (2023)
