Cristel Camacho, Ph.D. Assistant Professor School Medical School Department Green Ctr for Reprod Bio Scncs | Obstetrics and Gynecology Graduate Programs Cancer Biology Biography Download Curriculum Vitae Cristel Camacho is an Assistant Professor in the Cecil H. and Ida Green Center for Reproductive Biology Sciences and Department of Obstetrics and Gynecology. Dr. Camacho received a B.S. in Biology from Hardin-Simmons University in 2005 and completed her graduate research on the genetic events underlying radiation-induced gliomagenesis in the laboratory of Dr. Sandeep Burma at UT Southwestern Medical Center in 2012. She completed her postdoctoral research on the tumorigenic impact of DNA repair deficiency in the developing central nervous system in the laboratory of Dr. Peter J. McKinnon at St. Jude Children’s Research Hospital, Memphis, TN in 2017. Her current research focuses on characterizing the molecular basis of breast cancer phenotypes with an emphasis on PARP biology. Education Undergraduate Hardin-Simmons University (2005), Biology Graduate School Univ of Tx Southwestern Med Ct (2012), Cancer Biology Research Interest Cancer Biology Genomics Publications Featured Publications Nucleolar Localization of the RNA Helicase DDX21 Predicts Survival Outcomes in Gynecological Cancers. Aljardali MW, Kremer KM, Parker JE, Fleming E, Chen H, Lea JS, Kraus WL, Camacho CV, Cancer Res Commun 2024 May Oncohistone Mutations Occur at Functional Sites of Regulatory ADP-ribosylation. Huang D, Camacho CV, Martire S, Nagari A, Setlem R, Gong X, Edwards AD, Chiu SP, Banaszynski LA, Kraus WL, Cancer Res 2022 Apr Poly(ADP-ribose) Polymerase-1 Regulates Estrogen-Dependent Gene Expression in Estrogen Receptor a-Positive Breast Cancer Cells. Gadad SS, Camacho CV, Malladi V, Hutti CR, Nagari A, Kraus WL, Mol Cancer Res 2021 Jun Relaxin Modulates the Genomic Actions and Biological Effects of Estrogen in the Myometrium by Reducing Estrogen Receptor Alpha Phosphorylation. Tripathy S, Nagari A, Chiu SP, Nandu T, Camacho CV, Mahendroo M, Kraus WL, bioRxiv 2024 Apr A PARP14/TARG1-Regulated RACK1 MARylation Cycle Drives Stress Granule Dynamics in Ovarian Cancer Cells. Challa S, Nandu T, Kim HB, Gong A, Renshaw CW, Li WC, Tan X, Camacho CV, Chen J, Kraus WL, bioRxiv 2023 Oct Simultaneous Nbs1 and p53 inactivation in neural progenitors triggers High-Grade Gliomas (HGG). Reuss DE, Downing SM, Camacho CV, Wang YD, Piro RM, Herold-Mende C, Wang ZQ, Hofmann TG, Sahm F, von Deimling A, McKinnon PJ, Frappart PO, Neuropathol Appl Neurobiol 2023 Jun e12915 Functional Characterization of lncRNA152 as an Angiogenesis-Inhibiting Tumor Suppressor in Triple-Negative Breast Cancers. Kim DS, Camacho CV, Setlem R, Kim K, Malladi S, Hou TY, Nandu T, Gadad SS, Kraus WL, Mol Cancer Res 2022 Aug Development and characterization of new tools for detecting poly(ADP-ribose) in vitro and in vivo. Challa S, Ryu KW, Whitaker AL, Abshier JC, Camacho CV, Kraus WL, Elife 2022 Apr 11 Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers. Challa S, Khulpateea BR, Nandu T, Camacho CV, Ryu KW, Chen H, Peng Y, Lea JS, Kraus WL, Cell 2021 Jul Alternate therapeutic pathways for PARP inhibitors and potential mechanisms of resistance. Kim DS, Camacho CV, Kraus WL, Exp Mol Med 2021 Jan Results 1-10 of 21 1 2 3 Next Last Honors & Awards First Place RHIC & AGS Thesis Award, Brookhaven National Laboratory, 2013 Outstanding Young Alumni Award, Hardin-Simmons University, 2016
