Yi Yin, M.D., Ph.D. Titles and Appointments Assistant Professor School Medical School Department Radiation Oncology Education Medical School Hubei Medical College - China (1998), Medicine Graduate School Wuhan University (2001), Surgery Graduate School Peking University (2006), Surgery Research Interest Cancer metastasis Exploring rationale combinations to achieve synergy for cancer immunotherapy Targeting the dominant DNA repair pathway to avoid radiation resistance Understanding the molecular mechanisms of therapeutic resistance in cancers Publications CDK4/6 inhibitors promote PARP1 degradation and synergize with PARP inhibitors in non-small cell lung cancer Roggero CM, Ghosh AB, Devineni A, Ma S, Blatt E, Raj GV, Yin Y Translational Oncology 2025 Feb 52 CDK4/6 inhibitors promote PARP1 degradation and synergize with PARP inhibitors in non-small cell lung cancer Roggero CM, Ghosh AB, Devineni A, Ma S, Blatt E, Raj GV, Yin Y Translational Oncology 2025 Feb 52 UBE2J1 is the E2 ubiquitin-conjugating enzyme regulating androgen receptor degradation and antiandrogen resistance Rodriguez Tirado C, Wang C, Li X, Deng S, Gonzalez J, Johnson NA, Xu Y, Metang LA, Sundar Rajan M, Yang Y, Yin Y, Hofstad M, Raj GV, Zhang S, Lemoff A, He W, Fan J, Wang Y, Wang T, Mu P Oncogene 2024 Jan 43 265-280 Alterations in BRCA2 as Determinants of Therapy Response in Prostate Cancer Hofstad M, Huang EY, Woods A, Yin Y, Desai NB, Raj GV Critical reviews in oncogenesis 2022 27 Dynamic differences between DNA damage repair responses in primary tumors and cell lines Gilbreath C, Ma S, Yu L, Sonavane R, Roggero CM, Devineni A, Mauck R, Desai NB, Bagrodia A, Kittler R, Raj G, Yin Y Translational Oncology 2021 Jan 14 DNA-dependent protein kinase drives prostate cancer progression through transcriptional regulation of the Wnt signaling pathway Kothari V, Goodwin JF, Zhao SG, Drake JM, Yin Y, Chang SL, Evans JR, Wilder-Romans K, Gabbara K, Dylgjeri E, Chou J, Sun G, Tomlins SA, Mehra R, Hege K, Filvaroff EH, Schaeffer EM, Karnes RJ, Quigley DA, Rathkopf DE, He HH, Speers C, Spratt DE, Gilbert LA, Ashworth A, Chinnaiyan AM, Raj GV, Knudsen KE, Feng FY Clinical Cancer Research 2019 Sep 25 5608-5622 Discovery of a novel long noncoding RNA overlapping the LCK gene that regulates prostate cancer cell growth Ta HQ, Whitworth H, Yin Y, Conaway M, Frierson HF, Campbell MJ, Raj GV, Gioeli D Molecular Cancer 2019 Jun 18 BRD4 Promotes DNA Repair and Mediates the Formation of TMPRSS2-ERG Gene Rearrangements in Prostate Cancer Li X, Baek GH, Ramanand SG, Sharp A, Gao Y, Yuan W, Welti J, Rodrigues DN, Dolling D, Figueiredo I, Sumanasuriya S, Crespo M, Aslam A, Li R, Yin Y, Mukherjee B, Kanchwala M, Hughes AM, Halsey WS, Chiang CM, Xing C, Raj GV, Burma S, de Bono J, Mani RS Cell Reports 2018 Jan 22 796-808 Androgen receptor variants mediate DNA repair after prostate cancer irradiation Yin Y, Li R, Xu K, Ding S, Li J, Baek GH, Ramanand SG, Ding S, Liu Z, Gao Y, Kanchwala MS, Li X, Hutchinson R, Liu X, Woldu SL, Xing C, Desai NB, Feng FY, Burma S, De Bono JS, Dehm SM, Mani RS, Chen BP, Raj GV Cancer research 2017 Sep 77 4745-4754 Phosphatidylserine-targeting antibody induces M1 macrophage polarization and promotes myeloid-derived suppressor cell differentiation Yin Y, Huang X, Lynn KD, Thorpe PE Cancer Immunology Research 2013 Oct 1 256-268 Results 1-10 of 21 1 2 3 Next Last
