Angela Scheuerle, M.D. Titles and Appointments Professor Schools Medical School Departments Pediatrics | Eugene McDermott Center for Human Growth and Development | Pathology You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Dr. Angela Scheuerle fell in love with genetics as a sophomore in high school and never looked back. She now has the career that she wanted at the age of 15 – even though such a profession didn’t exist at the time. Learning the intricacies of the science is like learning the secret of a magic trick. Remember the “ah hah!” moment when you suddenly mastered a two-wheeler? Genetics is like that. Dr. Scheuerle graduated Magna Cum Laude as a biology major from Sewanee: The University of the South. She received her M.D. from The University of South Florida Morsani College of Medicine. Dr. Scheuerle completed a Pediatric Residency at Children’s Hospital Medical Center in Cincinnati, Ohio, and Medical Genetics Fellowship at Baylor College of Medicine. Her fellowship started just at the beginning of the Human Genome Project, so she got to “grow up” in genetics at a very exciting time: when it was possible to keep up with gene discoveries because it was about one every two weeks. She has also completed a fellowship in Clinical Ethics at the University of Chicago. Dr. Scheuerle is board certified in Clinical Genetics, Clinical Molecular Genetics, and Pediatrics. She started shadowing in a craniofacial clinic during high school, where she developed a specific interest in craniofacial malformations. She has practiced Clinical Genetics in Houston and then Dallas since 1995. From 2003 to 2014 she was in private practice at Tesserae Genetics at Medical City Dallas. At that time, she was adjunct faculty at UT Southwestern in the Program of Ethics in Science and Medicine and the Eugene McDermott Center for Human Development since 2000. She joined the Pediatric Division of Genetics and Metabolism as full faculty in September 2014. She holds secondary appointments as Professor in the McDermott Center and in the Department of Pathology, where she is also co-director of the Fellowship in Laboratory Genetics and Genomics. In addition to clinical practice, Dr. Scheuerle works in public health genetics and drug safety. She has worked with the Texas Department of State Health Services Birth Defects Epidemiology and Surveillance Branch since 1993. This Branch operates the Texas Birth Defect Registry, an active state surveillance system that monitors birth prevalence of congenital anomalies and genetic conditions. This became particularly important in 2016 with the Zika virus epidemic. In July 2016, she attended and participated in a workshop at the Centers for Disease Control and Prevention to define guidelines for evaluation and management of infants and children exposed to Zika virus. The Birth Defects Epidemiology and Surveillance Branch manages the Texas Center for Birth Defects Research and Prevention (TCBDRP), which performs and supports investigation into causes of birth defects. The TCBDRP participated in the 15-year, 10-state National Birth Defects Prevention Study, and Dr. Scheuerle served as the Geneticist for Texas’ contribution to that Study. She continues her involvement with research generated from both the state and national programs. In 1997, Dr. Scheuerle joined the Antiretroviral Pregnancy Registry (APR). This is an FDA-mandated, post-marketing exposure registry that began in 1989 as the Zidovudine in Pregnancy Registry. This multi-drug registry is one of the largest of its kind, monitoring pregnancy exposure of now over 40 HIV and Hepatitis medications. Dr. Scheuerle’s role as teratologist is to identify those cases in which exposure to one or more medications temporally associates with embryopathogenesis of the anomaly. She also serves on the scientific advisory and steering committees for the APR. Her Organ System Classification schema for categorizing birth defects is one of two recommended by the FDA for use in pharmaceutical pregnancy registry work. Dr. Scheuerle now participates in other pregnancy registries and provides similar consultative services to US- and European-based pharmaceutical companies. Education Medical School USF Health Morsani College of Medicine (1988) Residency University of Cincinnati/Children's Hospital Medical Center (1991), Pediatrics Fellowship Baylor College of Medicine/Texas Children's Hospital (1995), Medical Genetics Research Interest Public health genetics and birth defect surveillance Syndrome definition Teratogenic risks of prescription medication/drug safety Publications A Population-Based Assessment of Cancer Risk in Children With VACTERL Tark JY, Renwick A, Tettamanti G, Harris RD, Desrosiers TA, Olshan AF, Janitz AE, Scheurer ME, Shumate CJ, Scheuerle AE, Plon SE, Huff CD, Nordgren A, Luke B, Lupo PJ, Schraw JM American Journal of Medical Genetics, Part A 2026 May 200 1004-1011 Phenotypic and genotypic insights into concurrent tertiary trisomy for 9p and 18p Wright CA, Scheuerle AE, Wilson K, García R, Koduru P Molecular Cytogenetics 2025 Dec 18 Pathogenic XPO1 variants cause a dominant neurodevelopmental disorder van Oirsouw AS, Nedbalova P, Hancarova M, Prchal J, Prchalova D, Vlckova M, Bendova S, Monaghan KG, Dyer LM, Chen Y, Carere DA, te Bogt EA, Fisher H, Scheuerle AE, Riley S, Jain M, Mu W, Bodurtha JN, van Eerde AM, Stokman MF, Longo N, Balasubramanian M, Spiller M, Costain G, von der Lippe C, Tveten K, Jortveit M, Holla ØL, Isidor B, Cogné B, Glinton KE, Vuocolo B, Sierra RA, Angle B, Bontempo K, Koop K, Rabin R, Pappas J, Staffenberg DA, Joset P, Miny P, Filges I, Alali A, Vitalone K, Rosenfeld JA, Bi W, Bradbrook S, Perrier R, Ramanathan S, Gold JA, Palomares Bralo M, Ángeles Gómez-Cano M, Olney AH, Nielsen S, Ziegler A, Bonneau D, Prouteau C, Bruel AL, Caille-Benigni C, Lambert L, Yu AC, Robin NH, Goodloe D, Fischer J, Porrmann J, Hennig YD, Abou Jamra R, Herman I, Johnson IR, Hérissant L, Jouret G, van Gassen KL, van Binsbergen E, van der Zwaag B, Kamermans A, Oegema R, Sedlacek Z, Fenckova M, van Jaarsveld RH Genetics in Medicine 2025 Nov 27 Health Supervision for Children With 22q11.2 Deletion Syndrome: Clinical Report Author Collaboration Co, Scheuerle AE, Geleske TA, Merchant N, Goldenberg PC, Vergano S, Holm IA, Jones K, Kalish J, Monteil DC, Pritchard AB, Rasmussen SA, Russell B, Santoro SL, Trapane P, Weaver KN Pediatrics 2025 Aug 156 Birth Defects and Adverse Pregnancy Outcomes in Hospital-based Birth Surveillance in Eswatini Gill MM, Khumalo PN, Hoffman HJ, Chouraya C, Kunene M, Dlamini F, Tukei V, Scheuerle AE, Nhlabatsi B, Mofenson L Pediatric Infectious Disease Journal 2025 May 44 431-438 Maternal Diarrhea During the Periconceptional Period and the Risk of Birth Defects, National Birth Defects Prevention Study, 2006–2011 Author Collaboration tN, Waller DK, Mohan Dass NL, Oluwafemi OO, Agopian AJ, Tark JY, Hoyt AT, Scheuerle AE, Canfield MA Birth Defects Research 2025 Feb 117 Pharmacovigilance Pregnancy Data in a Population of Japanese Patients With Chronic Inflammatory Disease Exposed to Certolizumab Pegol Goto M, Saito S, Scheuerle AE, Yasuda S, Houston N, Kumke T, Lauwerys B, Murashima A International Journal of Rheumatic Diseases 2025 Jan 28 Classification of isolated versus multiple birth defects: An automated process for population-based registries Benjamin RH, Nguyen JM, Drummond-Borg M, Scheuerle AE, Langlois PH, Canfield MA, Shumate CJ, Mitchell LE, Agopian AJ American Journal of Medical Genetics, Part A 2024 Oct 194 The Antiretroviral Pregnancy Registry: Three decades of prospective monitoring for birth defects Albano JD, Scheuerle AE, Watts DH, Beckerman KP, Mofenson LM, Pikis A, Vannappagari V, Seekins D, Cook TS, Tilson H Pharmacoepidemiology and Drug Safety 2024 Jun 33 Prevalence and descriptive epidemiology of choanal atresia and stenosis in Texas, 1999–2018 Benjamin RH, Marengo LK, Scheuerle AE, Agopian AJ, Mitchell LE American Journal of Medical Genetics, Part A 2024 Jun 194 Results 1-10 of 147 1 2 3 4 5 Next Last Books Featured Books Appendix III: Syndromes Glossary. In Cabana MD, ed. The 5-Minute Pediatric Consult. 7th ed. Scheuerle AE. (2015). Wolters Kluwer; 1027-1033. Genetics in the Clinic: Clinical, Ethical and Social Implications for Primary Care. (Ed.) (2001). St. Louis: Mosby Understanding Genetics: A Guide for Couples and Families. (Ed.) (2005). Westport, CT: Greenwood Publishing. Clinical Genetics and Dysmorphology. In Cabana M, ed. Rudolph's Pediatrics Self-Assessment and Board Review. 22nd ed. Scheuerle A. (2014). San Francisco: McGraw Hill; 220-236. Review of Embryology and Clinical Genetics. In Advances in Plastic Surgery. Scheuerle A. (1998). Honors & Awards Texas Super DoctorTexas Monthly (2018) Best Pediatric Specialists/Doctors in DallasD Magazine (2010-2018) Distinguished Service AwardNational Birth Defect Prevention Network (2010) First place poster awardNational Birth Defect Prevention Network (2009) Phi Beta Kappa (1994) Professional Associations/Affiliations AAP - Council on Genetics (1995-2019) AAP - ListServ Working Group (2011) AAP - Section Executive Committee (2013-2015) American Academy of Pediatrics (AAP) (1988) American College of Medical Genetics and Genomics (1995) American Society of Human Genetics (1990) Bioethics Committee, Medical City Dallas Hospital (2003-2014) Houston Bioethics Network (1997-1998) National Birth Defects Prevention Network (1998) North Texas Bioethics Network (2005) Pediatric Society of Greater Dallas (2004)
