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Jyothsna Gattineni, M.D.

Jyothsna Gattineni, M.D.

Titles and Appointments

Chief, Division of Pediatric Nephrology

Associate Professor & Division Chief

Schools
Medical School
Departments
Pediatrics

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  • Biography

    Jyothsna Gattineni, M.D., earned her medical degree from Stanley Medical College and Hospital in Chennai, India. She subsequently completed residencies in pediatrics in the United Kingdom and at Driscoll Children’s Hospital in Corpus Christi, Texas. Dr. Gattineni then completed a pediatric nephrology fellowship at UT Southwestern/Children’s Medical Center. Dr. Gattineni practices at UT Southwestern and Children’s Health and serves as Chief of Pediatric Nephrology at both institutions. 

    One of the largest pediatric nephrology programs nationwide, UT Southwestern’s Division of Pediatric Nephrology is the main provider of clinical and testing services for children with kidney disease, bone disease, and hypertension at Children’s Medical Center Dallas and Children’s Medical Center Plano.

    As an NIH-funded physician-scientist, Dr. Gattineni aims to better understand kidney disease and open the door to new treatments. Her research focuses on understanding the fibroblast growth factor 23 (FGF23) hormone and how it impacts patients with chronic kidney disease. Her lab has characterized the receptors for this hormone, and in doing so, generated a mouse model with a 25- to 50-fold increase in FGF23 levels. Dr. Gattineni is using this model to determine if elevated FGF23 contributes to the bone, vascular, and cardiac disease seen in patients with chronic kidney disease.

  • Education
    Medical School
    Stanley Medical College and Hospital (1994)
    Residency
    Govt. Stanley Medical College Hospital (1995), Internal Medicine & Pediatrics
    Residency
    The Royal Bolton Hospital (2003), Pediatrics
    Residency
    Driscoll Children's Hospital - GME (2005), Pediatrics
    Fellowship
    UT Southwestern/Children's Medical Center (2008), Pediatric Nephrology
    Fellowship
    UT Southwestern Medical Center (2009), Nephrology
  • Research Interest
    • Chronic kidney disease
    • FGF23 and its receptors
    • Hemolytic uremic syndrome
    • Phosphate homeostasis and disorders of phosphate metabolism
    • Tubular Transport
  • Publications
    Updates in atypical hemolytic syndrome
    Drake K, Gattineni J Current opinion in pediatrics 2026 Apr 38 219-225
    Pediatric Nephrology Practice in the United States: Survey of Pediatric Nephrology Division Directors
    Author Collaboration AD, Verghese PS, Bobrowski A, Carter C, Dharnidharka VR, Gattineni J, Goodwin JE, Kershaw DB, Mauch TJ, Nelson R, Subtirelu M, Flynn J, Feig D American Journal of Kidney Diseases 2025 Jul 86 74-83
    Acetaminophen induced high anion gap metabolic acidosis: a potentially under-recognized consequence from a common medication
    Gaur D, Michalopulos MG, Drake KA, Gattineni J Pediatric Nephrology 2025 Jan 40 99-101
    The role of fibroblast growth factor 23 in regulation of phosphate balance
    Wilson R, Mukherjee-Roy N, Gattineni J Pediatric Nephrology 2024 Dec 39 3439-3451
    Correction: Use of ClearGuard HD caps in pediatric hemodialysis patients (Pediatric Nephrology, (2024), 39, 7, (2171-2175), 10.1007/s00467-023-06273-6)
    Nau A, Richardson T, Cardwell D, Ehrlich J, Gattineni J, Hanna M, Keswani M, Neibauer E, Nitz K, Quigley R, Rheault M, Sims R, Woo M, Warady BA Pediatric Nephrology 2024 Aug 39 2541
    Use of ClearGuard HD caps in pediatric hemodialysis patients
    Nau A, Richardson T, Cardwell D, Ehrlich J, Gattineni J, Hanna M, Keswani M, Neibauer E, Nitz K, Quigley R, Rheault M, Sims R, Woo M, Warady BA Pediatric Nephrology 2024 Jul 39 2171-2175
    C3 glomerulopathy in a patient with a history of post-infectious glomerulonephritis
    Nnadi N, Hendricks AR, Torrealba JR, Drake KA, Gattineni J Pediatric Nephrology 2024 Mar 39 745-748
    Familial hyperkalemic hypertension: hyperkalemia not hypertension defines dominant KLHL3 disease and may permit earlier recognition and tailored therapy
    Sambharia M, Gattineni J, Noureddine L, Mansilla MA, Thomas CP Journal of Nephrology 2022 Jul 35 1737-1742
    The mammalian SKIV2L RNA exosome is essential for early B cell development
    Yang K, Han J, Gill JG, Park JY, Sathe MN, Gattineni J, Wright T, Wysocki C, de la Morena MT, Yan N Science Immunology 2022 May 7
    Cytoplasmic RNA quality control failure engages mTORC1-mediated autoinflammatory disease
    Yang K, Han J, Asada M, Gill JG, Park JY, Sathe MN, Gattineni J, Wright T, Wysocki CA, Teresa de la Morena M, Garza LA, Yan N Journal of Clinical Investigation 2022 Jan 132
  • Books

    Featured 

  • Honors & Awards
    • Best Pediatric Faculty Teaching Award
      UT Southwestern Medical Center and Children's Health, Dallas (2020)
    • Top 5 Capstone Projects
      LEAD Program, UT Southwestern Medical Center, Dallas (2019)
    • Editorial Board
      Pediatric Nephrology (2018)
    • Best Pediatric Specialists/Doctors in Dallas
      D Magazine (2017-2022)
    • Society of Pediatric Research
      Member (2011)
    • Best Resident Research Presentation
      Driscoll's Children's Hospital, Texas A&M University, Corpus Christi, Texas (2005)
    • Best Resident Case Presentation
      Driscoll's Children's Hospital, Texas A&M University, Corpus Christi, Texas (2004)
    • DFW Mom Approved Pediatricians
  • Professional Associations/Affiliations
    • American Academy of Pediatrics (2017)
    • American Society of Nephrology (2005)
    • American Society of Pediatric Nephrology (2009)
    • International Pediatric Nephrology Association (2009)
    • International Society of Nephrology (2009)
    • Society of Pediatric Research (2011)