Lianghao Ding, Ph.D.

Graduate School

Tohoku University (2001)

• Carcinogenic risk from charged particle exposures in space
• Circulating miRNAs as biomarkers for cancer diagnosis and therapy
• Genomics and NGS data analysis

Featured Publications

Elucidation of changes in molecular signalling leading to increased cellular transformation in oncogenically progressed human bronchial epithelial cells exposed to radiations of increasing LET.

Ding LH, Park S, Xie Y, Girard L, Minna JD, Story MD Mutagenesis 2015 May

Distinct transcriptome profiles identified in normal human bronchial epithelial cells after exposure to ?-rays and different elemental particles of high Z and energy.

Ding LH, Park S, Peyton M, Girard L, Xie Y, Minna JD, Story MD BMC Genomics 2013 14 372

Defining molecular and cellular responses after low and high linear energy transfer radiations to develop biomarkers of carcinogenic risk or therapeutic outcome.

Story M, Ding LH, Brock WA, Ang KK, Alsbeih G, Minna J, Park S, Das A Health Phys 2012 Nov 103 5 596-606

Enhanced identification and biological validation of differential gene expression via Illumina whole-genome expression arrays through the use of the model-based background correction methodology.

Ding LH, Xie Y, Park S, Xiao G, Story MD Nucleic Acids Res. 2008 Jun 36 10 e58

Gene expression changes in normal human skin fibroblasts induced by HZE-particle radiation.

Ding LH, Shingyoji M, Chen F, Chatterjee A, Kasai KE, Chen DJ Radiat. Res. 2005 Oct 164 4 Pt 2 523-6

Gene expression profiles of normal human fibroblasts after exposure to ionizing radiation: a comparative study of low and high doses.

Ding LH, Shingyoji M, Chen F, Hwang JJ, Burma S, Lee C, Cheng JF, Chen DJ Radiat. Res. 2005 Jul 164 1 17-26

A case-control genome-wide association study identifies genetic modifiers of fetal hemoglobin in sickle cell disease.

Liu L, Pertsemlidis A, Ding LH, Story MD, Steinberg MH, Sebastiani P, Hoppe C, Ballas SK, Pace BS Exp. Biol. Med. (Maywood) 2016 Mar

Strain background determines lymphoma incidence in atm knockout mice.

Genik PC, Bielefeldt-Ohmann H, Liu X, Story MD, Ding L, Bush JM, Fallgren CM, Weil MM Neoplasia 2014 Feb 16 2 129-IN7

Characterization of Transcription Factor Networks Involved in Umbilical Cord Blood CD34+ Stem Cells-Derived Erythropoiesis.

Li B, Ding L, Yang C, Kang B, Liu L, Story MD, Pace BS PLoS ONE 2014 9 9 e107133

Molecular characterisation of murine acute myeloid leukaemia induced by 56Fe ion and 137Cs gamma ray irradiation.

Steffen LS, Bacher JW, Peng Y, Le PN, Ding LH, Genik PC, Ray FA, Bedford JS, Fallgren CM, Bailey SM, Ullrich RL, Weil MM, Story MD Mutagenesis 2013 Jan 28 1 71-9