Ruth Dubin, M.D.

Ruth Dubin, M.D., is an Associate Professor in the Department of Internal Medicine at UT Southwestern, and a member of the Division of Nephrology and the Center for Mineral Metabolism and Clinical Research. She practices nephrology at the Dallas VAMC and Clements University Hospital.

Originally from Somerville, New Jersey, Dr. Dubin holds a bachelor's degree with honors in fine arts and comparative literature from Yale University in New Haven, Connecticut. She earned her medical degree from the University of California San Francisco and completed internal medicine residency training at UT Southwestern Medical Center. She completed a fellowship in nephrology at the University of California San Francisco.

Dr. Dubin joined the UT Southwestern faculty in 2022. 

Dr. Dubin’s research concerning cardiovascular disease among patients with chronic kidney disease has been funded by the NIH since 2012 when she received a K23 award. Dr. Dubin is Principal Investigator on two R01’s involving the use of large-scale proteomics to research cardiovascular disease. She leads an R01 to discover novel protein markers and mediators of cardiovascular disease among patients with end-stage renal disease(ESRD) in the Chronic Renal Insufficiency Cohort, the Predictors of Arrhythmic and Cardiovascular Risk in the ESRD cohort, and the Frequent Hemodialysis Network. She is a co-principal investigator on an R01 for studying large-scale proteomics in the Multi-Ethnic Study of Atherosclerosis. Dr. Dubin utilizes conventional epidemiological methods, newer machine learning algorithms, and genome-wide association studies to build novel risk models and identify potential therapeutic targets. Her papers have been published in journals such as Hypertension, European Heart Journal, and Clinical Journal of the American Society of Nephrology.

Dr. Dubin is active in several professional societies. She is an American Society of Nephrology Fellow, a Principal Investigator for the NIDDK Biomarker Consortium, and a member of the MESA Omics Design Group for the NHLBI Trans-omics for Precision Medicine. She is also currently an Ad Hoc Reviewer for the Clinical Journal of the American Society of Nephrology and Hemodialysis International.

Medical School

University of California at San Francisco (2005)

Residency

UT Southwestern Medical Center (2008), Internal Medicine

Fellowship

University of California at San Francisco (2011), Nephrology

Featured Publications

Identification of Novel Biomarkers and Pathways for Coronary Artery Calcification in Nondiabetic Patients on Hemodialysis Using Metabolomic Profiling.

Chen W, Fitzpatrick J, Sozio SM, Jaar BG, Estrella MM, Riascos-Bernal DF, Wu TT, Qiu Y, Kurland IJ, Dubin RF, Chen Y, Parekh RS, Bushinsky DA, Sibinga NES, Kidney360 2021 Feb 2 2 279-289

Proteomics and Metabolomics in Kidney Disease, including Insights into Etiology, Treatment, and Prevention.

Dubin RF, Rhee EP, Clin J Am Soc Nephrol 2020 03 15 3 404-411

Predictors of high sensitivity cardiac troponin T in chronic kidney disease patients: a cross-sectional study in the chronic renal insufficiency cohort (CRIC).

Dubin RF, Li Y, He J, Jaar BG, Kallem R, Lash JP, Makos G, Rosas SE, Soliman EZ, Townsend RR, Yang W, Go AS, Keane M, Defilippi C, Mishra R, Wolf M, Shlipak MG, BMC Nephrol 2013 Oct 14 229

Associations of pentraxin-3 with cardiovascular events, incident heart failure, and mortality among persons with coronary heart disease: data from the Heart and Soul Study.

Dubin R, Li Y, Ix JH, Shlipak MG, Whooley M, Peralta CA, Am Heart J 2012 Feb 163 2 274-9

Associations of endothelial dysfunction and arterial stiffness with intradialytic hypotension and hypertension.

Dubin R, Owens C, Gasper W, Ganz P, Johansen K, Hemodial Int 2011 Jul 15 3 350-8

Racial differences in the association of pentraxin-3 with kidney dysfunction: the Multi-Ethnic Study of Atherosclerosis.

Dubin R, Shlipak M, Li Y, Ix J, de Boer IH, Jenny N, Peralta CA, Nephrol Dial Transplant 2011 Jun 26 6 1903-8

Kidney function and multiple hemostatic markers: cross sectional associations in the multi-ethnic study of atherosclerosis.

Dubin R, Cushman M, Folsom AR, Fried LF, Palmas W, Peralta CA, Wassel C, Shlipak MG, BMC Nephrol 2011 Jan 12 3

Kidney function decline in the elderly: impact of lipoprotein-associated phospholipase A(2).

Peralta CA, Katz R, Shlipak M, Dubin R, DeBoer I, Jenny N, Fitzpatrick A, Koro C, Kestenbaum B, Ix J, Sarnak M, Cushman M, Am J Nephrol 2011 34 6 512-8

Secretion of lactoferrin and lysozyme by cultures of human airway epithelium.

Dubin RF, Robinson SK, Widdicombe JH, Am J Physiol Lung Cell Mol Physiol 2004 Apr 286 4 L750-5

Resistance of differentiated human airway epithelium to infection by rhinovirus.

Lopez-Souza N, Dolganov G, Dubin R, Sachs LA, Sassina L, Sporer H, Yagi S, Schnurr D, Boushey HA, Widdicombe JH, Am J Physiol Lung Cell Mol Physiol 2004 Feb 286 2 L373-81

• Hardest Working Fellow Award
  (2009)

• American Society of Nephrology (2019)
• American Society of Nephrology (2019)
• NHLBI Trans-omics for Precision Medicine (2022)
• NIDDK Biomarker Consortium (2016)