Education

Undergraduate
Bilkent University (2005), Genetics
Graduate School
UT Southwestern Medical Center (2010), Cancer Biology

Research Interest

  • Immunotherapy
  • Lung cancer development
  • Role of metabolic dysregulation in host-tumor interactions
  • Tumor microenvironment

Publications

Featured Publications LegendFeatured Publications

Assessing Therapeutic Efficacy of MEK Inhibition in a KRAS G12C-Driven Mouse Model of Lung Cancer.
Li S, Liu S, Deng J, Akbay EA, Hai J, Ambrogio C, Zhang L, Zhou F, Jenkins RW, Adeegbe DO, Gao P, Wang X, Paweletz CP, Herter-Sprie GS, Chen T, Gutierrez Quiceno L, Zhang Y, Merlino AA, Quinn MM, Zeng Y, Yu X, Liu Y, Fan L, Aguirre AJ, Barbie DA, Yi X, Wong KK Clin. Cancer Res. 2018 Jun
JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.
McKenney AS, Lau AN, Somasundara AVH, Spitzer B, Intlekofer AM, Ahn J, Shank K, Rapaport FT, Patel MA, Papalexi E, Shih AH, Chiu A, Freinkman E, Akbay EA, Steadman M, Nagaraja R, Yen K, Teruya-Feldstein J, Wong KK, Rampal R, Heiden MGV, Thompson CB, Levine RL J. Clin. Invest. 2018 Jan
Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2.
Zhang H, Fillmore Brainson C, Koyama S, Redig AJ, Chen T, Li S, Gupta M, Garcia-de-Alba C, Paschini M, Herter-Sprie GS, Lu G, Zhang X, Marsh BP, Tuminello SJ, Xu C, Chen Z, Wang X, Akbay EA, Zheng M, Palakurthi S, Sholl LM, Rustgi AK, Kwiatkowski DJ, Diehl JA, Bass AJ, Sharpless NE, Dranoff G, Hammerman PS, Ji H, Bardeesy N, Saur D, Watanabe H, Kim CF, Wong KK Nat Commun 2017 Apr 8 14922
Co-clinical quantitative tumor volume imaging in ALK-rearranged NSCLC treated with crizotinib.
Nishino M, Sacher AG, Gandhi L, Chen Z, Akbay E, Fedorov A, Westin CF, Hatabu H, Johnson BE, Hammerman P, Wong KK Eur J Radiol 2017 Mar 88 15-20
Development of Selective Covalent Janus Kinase 3 Inhibitors.
Tan L, Akahane K, McNally R, Reyskens KM, Ficarro SB, Liu S, Herter-Sprie GS, Koyama S, Pattison MJ, Labella K, Johannessen L, Akbay EA, Wong KK, Frank DA, Marto JA, Look TA, Arthur JS, Eck MJ, Gray NS J. Med. Chem. 2015 Aug 58 16 6589-606
Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models.
Herter-Sprie GS, Korideck H, Christensen CL, Herter JM, Rhee K, Berbeco RI, Bennett DG, Akbay EA, Kozono D, Mak RH, Mike Makrigiorgos G, Kimmelman AC, Wong KK Nat Commun 2014 Dec 5 5870

Honors & Awards

  • Cancer Prevention and Research Institute of Texas (CPRIT) Scholar Award
    (2016-2020)
  • International Association of the Study of Lung Cancer (IASLC) Young Investigator Award
    (2016-2017)
  • William Guy Forbeck Foundation Scholar Award
    (2015-2015)
  • American Association of Cancer Research (AACR)- Women in Cancer Research Scholar Award
    (2014-2014)
  • Outstanding Cancer Related Poster Award at the Simmons Comprehensive Cancer Center 3rd Annual Scientific Retreat, UT Southwestern Medical Center
    (2008-2008)

Professional Associations/Affiliations

  • American Association for Cancer Research (AACR)
  • American Society of Clinical Oncology (ASCO)
  • International Association of the Study of Lung Cancer (IASLC)