Education

Undergraduate
Uni of California-Davis (1992), Biology
Graduate School
University of Texas-Austin (1999), Zoology

Research Interest

  • Cancer
  • Developmental Biology
  • Metabolism
  • Single cell transcriptomics
  • Stem/progenitor cells
  • Tissue engineering and regeneration

Publications

Featured Publications LegendFeatured Publications

Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme.
Rajagopal J, Carroll TJ, Guseh JS, Bores SA, Blank LJ, Anderson WJ, Yu J, Zhou Q, McMahon AP, Melton DA Development 2008 May 135 9 1625-34
Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state.
Marose TD, Merkel CE, McMahon AP, Carroll TJ. Dev. Biol. February 2008 314(1) 112-26
Mutations of HNF-1beta inhibit epithelial morphogenesis through dysregulation of SOCS-3.
Ma Z, Gong Y, Patel V, Karner CM, Fischer E, Hiesberger T, Carroll TJ, Pontoglio M, Igarashi P Proc. Natl. Acad. Sci. U.S.A. 2007 Dec 104 51 20386-91
Molecular regulation of kidney development: is the answer blowing in the Wnt?
Merkel CE, Karner CM, Carroll TJ Pediatr. Nephrol. 2007 Nov 22 11 1825-38
Noncanonical Wnt signaling through G protein-linked PKCdelta activation promotes bone formation.
Tu X, Joeng KS, Nakayama KI, Nakayama K, Rajagopal J, Carroll TJ, McMahon AP, Long F Dev. Cell 2007 Jan 12 1 113-27
Wnt9b is the mutated gene involved in multifactorial nonsyndromic cleft lip with or without cleft palate in A/WySn mice, as confirmed by a genetic complementation test.
Juriloff DM, Harris MJ, McMahon AP, Carroll TJ, Lidral AC Birth Defects Res. Part A Clin. Mol. Teratol. 2006 Aug 76 8 574-9
Apical-basal polarity, Wnt signaling and vertebrate organogenesis.
Karner C, Wharton KA, Carroll TJ Semin. Cell Dev. Biol. 2006 Apr 17 2 214-22
Planar cell polarity and vertebrate organogenesis.
Karner C, Wharton KA, Carroll TJ Semin. Cell Dev. Biol. 2006 Apr 17 2 194-203
Apoptosis induced by vitamin A signaling is crucial for connecting the ureters to the bladder.
Batourina E, Tsai S, Lambert S, Sprenkle P, Viana R, Dutta S, Hensle T, Wang F, Niederreither K, McMahon AP, Carroll TJ, Mendelsohn CL Nat. Genet. 2005 Oct 37 10 1082-9
WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature.
Lobov IB, Rao S, Carroll TJ, Vallance JE, Ito M, Ondr JK, Kurup S, Glass DA, Patel MS, Shu W, Morrisey EE, McMahon AP, Karsenty G, Lang RA Nature 2005 Sep 437 7057 417-21

Honors & Awards

  • A.S.N. Gottschalk Career Development Award
    (2005)
  • A.H.A. Scientist Development Grant
    (0)

Professional Associations/Affiliations

  • American Society for Nephrology
  • Society for Developmental Biology