Education

Undergraduate
Uni of California-Davis (1992), Biology
Graduate School
University of Texas-Austin (1999), Zoology

Research Interest

  • Cancer
  • Developmental Biology
  • Metabolism
  • Single cell transcriptomics
  • Stem/progenitor cells
  • Tissue engineering and regeneration

Publications

Featured Publications LegendFeatured Publications

MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma.
Bailey ST, Smith AM, Kardos J, Wobker SE, Wilson HL, Krishnan B, Saito R, Lee HJ, Zhang J, Eaton SC, Williams LA, Manocha U, Peters DJ, Pan X, Carroll TJ, Felsher DW, Walter V, Zhang Q, Parker JS, Yeh JJ, Moffitt RA, Leung JY, Kim WY Nat Commun 2017 Jun 8 15770
(Re)Building a Kidney.
Oxburgh L, Carroll TJ, Cleaver O, Gossett DR, Hoshizaki DK, Hubbell JA, Humphreys BD, Jain S, Jensen J, Kaplan DL, Kesselman C, Ketchum CJ, Little MH, McMahon AP, Shankland SJ, Spence JR, Valerius MT, Wertheim JA, Wessely O, Zheng Y, Drummond IA J. Am. Soc. Nephrol. 2017 Jan
Cdc42 regulates epithelial cell polarity and cytoskeletal function in kidney tubule development.
Elias BC, Das A, Parekh DV, Mernaugh G, Adams R, Yang Z, Brakebusch C, Pozzi A, Marciano DK, Carroll TJ, Zent R J. Cell. Sci. 2015 Oct
Wnt4 Is essential to normal mammalian lung development.
Caprioli A, Villasenor A, Wylie LA, Braitsch C, Marty-Santos L, Barry D, Karner CM, Fu S, Meadows SM, Carroll TJ, Cleaver O Dev. Biol. 2015 Aug
A Cre-inducible fluorescent reporter for observing apical membrane dynamics.
Pan X, Schnell U, Karner CM, Small EV, Carroll TJ Genesis 2015 Mar
The development of highly potent inhibitors for porcupine.
Wang X, Moon J, Dodge ME, Pan X, Zhang L, Hanson JM, Tuladhar R, Ma Z, Shi H, Williams NS, Amatruda JF, Carroll TJ, Lum L, Chen C J. Med. Chem. 2013 Mar 56 6 2700-4
Generation and characterization of KsprtTA and KsptTA transgenic mice.
Pan X, Small EV, Igarashi P, Carroll TJ Genesis 2013 Feb
Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine.
Dodge ME, Moon J, Tuladhar R, Lu J, Jacob LS, Zhang LS, Shi H, Wang X, Moro E, Mongera A, Argenton F, Karner CM, Carroll TJ, Chen C, Amatruda JF, Lum L J. Biol. Chem. 2012 Jun 287 27 23246-54
The kidney and planar cell polarity.
Carroll TJ, Yu J Curr. Top. Dev. Biol. 2012 101 185-212
The Leucine Zipper Putative Tumor Suppressor 2 Protein LZTS2 Regulates Kidney Development.
Peng Y, Clark C, Luong R, Tu WH, Lee J, Johnson DT, Das A, Carroll TJ, Sun Z J. Biol. Chem. 2011 Nov 286 46 40331-42

Honors & Awards

  • A.S.N. Gottschalk Career Development Award
    (2005)
  • A.H.A. Scientist Development Grant
    (0)

Professional Associations/Affiliations

  • American Society for Nephrology
  • Society for Developmental Biology