Biography

My research program is involved in analyzing genetics of bacteria and requirements of bacteria to interact with appropriate hosts.  The primary research interests of the laboratory are focused towards Campylobacter jejuni, a leading cause of diarrheal disease throughout the world, and Helicobacter pylori, a primary cause of gastritis, gastric ulcers, and gastric cancer.  My laboratory identifies factors required by these bacteria for infection of hosts and analyzes the regulated expression of these factors.  Further detalis regarding my research program can be found at:  http://www4.utsouthwestern.edu/hendrixsonlab/Hendrixson_Lab/Hendrixson_Lab_Home.html.

Education

Undergraduate
Univ Arkansas Fayetteville (1994), Microbiology
Graduate School
Washington Univ-Sch of Medicin (1999), Microbiology

Research Interest

  • Bacterial Genetics
  • Bacterial Pathogenesis
  • Bacterial-Host Interactions
  • Campylobacter jejuni
  • Helicobacter pylori

Publications

Featured Publications LegendFeatured Publications

EptC of Campylobacter jejuni mediates phenotypes involved in host interactions and virulence.
Cullen TW, O'Brien JP, Hendrixson DR, Giles DK, Hobb RI, Thompson SA, Brodbelt JS, Trent MS Infect. Immun. 2013 Feb 81 2 430-40
Architecture of the major component of the type III secretion system export apparatus.
Abrusci P, Vergara-Irigaray M, Johnson S, Beeby MD, Hendrixson DR, Roversi P, Friede ME, Deane JE, Jensen GJ, Tang CM, Lea SM Nat. Struct. Mol. Biol. 2013 Jan 20 1 99-104
Functional analysis of the RdxA and RdxB nitroreductases of Campylobacter jejuni reveals that mutations in rdxA confer metronidazole resistance.
Ribardo DA, Bingham-Ramos LK, Hendrixson DR J. Bacteriol. 2010 Apr 192 7 1890-901
FlhF and its GTPase activity are required for distinct processes in flagellar gene regulation and biosynthesis in Campylobacter jejuni.
Balaban M, Joslin SN, Hendrixson DR J. Bacteriol. 2009 Nov 191 21 6602-11
Activation of the Campylobacter jejuni FlgSR two-component system is linked to the flagellar export apparatus.
Joslin SN, Hendrixson DR J. Bacteriol. 2009 Apr 191 8 2656-67
Restoration of flagellar biosynthesis by varied mutational events in Campylobacter jejuni.
Hendrixson DR Mol. Microbiol. 2008 Oct 70 2 519-36
Analysis of the Campylobacter jejuni FlgR response regulator suggests integration of diverse mechanisms to activate an NtrC-like protein.
Joslin SN, Hendrixson DR J. Bacteriol. 2008 Apr 190 7 2422-33
Characterization of two putative cytochrome c peroxidases of Campylobacter jejuni involved in promoting commensal colonization of poultry.
Bingham-Ramos LK, Hendrixson DR Infect. Immun. 2008 Mar 76 3 1105-14
Analysis of the roles of FlgP and FlgQ in flagellar motility of Campylobacter jejuni.
Sommerlad SM, Hendrixson DR J. Bacteriol. 2007 Jan 189 1 179-86
A phase-variable mechanism controlling the Campylobacter jejuni FlgR response regulator influences commensalism.
Hendrixson DR Mol. Microbiol. 2006 Sep 61 6 1646-59