2014 - present Associate Professor, Dept. of Biochemistry, UT Southwestern

2010 – 2014 Assistant Professor, Dept. of Biochemistry and Internal Medicine, UT Southwestern

2004 - 2010 Assistant Professor, Dept. of Internal Medicine, UT Southwestern

1999 - 2004 Postdoctoral Fellow in Professor Ellenberger’s group, Dept. of Biological Chemistry and Molecular Pharmacology, Harvard Medical School

1998 - 1999 Postdoctoral Fellow in Professor Hakoshima’s group at Dept. of Molecular Biology, Nara Institute of Science and Technology

Research Interest

  • Amyloid-like fiber
  • Biochemistry
  • Fluorescent microscopy
  • Protein-protein and protein-RNA/DNA interaction
  • RNA granules
  • RNA regulation
  • X-ray crystallography


Featured Publications LegendFeatured Publications

TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics.
Mackenzie IR, Nicholson AM, Sarkar M, Messing J, Purice MD, Pottier C, Annu K, Baker M, Perkerson RB, Kurti A, Matchett BJ, Mittag T, Temirov J, Hsiung GR, Krieger C, Murray ME, Kato M, Fryer JD, Petrucelli L, Zinman L, Weintraub S, Mesulam M, Keith J, Zivkovic SA, Hirsch-Reinshagen V, Roos RP, Züchner S, Graff-Radford NR, Petersen RC, Caselli RJ, Wszolek ZK, Finger E, Lippa C, Lacomis D, Stewart H, Dickson DW, Kim HJ, Rogaeva E, Bigio E, Boylan KB, Taylor JP, Rademakers R Neuron 2017 Aug 95 4 808-816.e9
Cross-ß polymerization and hydrogel formation by low-complexity sequence proteins.
Kato M, Lin Y, McKnight SL Methods 2017 Jun
Toxic PRn poly-dipeptides encoded by the C9orf72 repeat expansion block nuclear import and export.
Shi KY, Mori E, Nizami ZF, Lin Y, Kato M, Xiang S, Wu LC, Ding M, Yu Y, Gall JG, McKnight SL Proc. Natl. Acad. Sci. U.S.A. 2017 Jan
Cross-ß Polymerization of Low Complexity Sequence Domains.
Kato M, McKnight SL Cold Spring Harb Perspect Biol 2016 Nov
An Atypical Tropomyosin in Drosophila with Intermediate Filament-like Properties.
Cho A, Kato M, Whitwam T, Kim JH, Montell DJ Cell Rep 2016 Jul 16 4 928-38

Honors & Awards

  • HFSP Young Investigators Award
  • 20th International Union of Biochemistry and Molecular Biology (IUBMB) congress Young Scientist Program
  • Uehara Memorial Foundation
  • Japan Society for the Promotion of Science for Abroad
  • Japan Society for the Promotion of Science for Young Scientists