Lily Huang, Ph.D. Associate Professor School Medical School Department Cell Biology Graduate Programs Cancer Biology, Cell and Molecular Biology Biography Download Curriculum Vitae Education Undergraduate National Taiwan University , Chemistry Graduate School University of California-San D (1997) Research Interest Cancer Cytokine receptor Hematopoiesis Signal transduction Structure-function analysis of protein Publications Featured Publications Epo-IGF1R crosstalk expands stress-specific progenitors in regenerative erythropoiesis and myeloproliferative neoplasm. Hsieh HH, Yao H, Ma Y, Zhang Y, Xiao X, Stephens H, Wajahat N, Chung SS, Xu L, Xu J, Rampal RK, Huang LJ, Blood 2022 Sep Deletion of miR-451 curbs JAK2(V617F)-induced erythrocytosis in polycythemia vera by oxidative stress-mediated erythroblast apoptosis and hemolysis. Yao H, Ma Y, Huang LJ, Haematologica 2020 04 105 4 e153-e156 Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9. Zhang LS, Kang X, Lu J, Zhang Y, Wu X, Wu G, Zheng J, Tuladhar R, Shi H, Wang Q, Morlock L, Yao H, Huang LJ, Maire P, Kim J, Williams N, Xu J, Chen C, Zhang CC, Lum L EBioMedicine 2019 Jan 39 145-158 Effects of erythropoietin receptor activity on angiogenesis, tubular injury, and fibrosis in acute kidney injury: a "U-shaped" relationship. Shi M, Flores B, Li P, Gillings N, McMillan KL, Ye J, Huang LJ, Sidhu SS, Zhong YP, Grompe MT, Streeter PR, Moe OW, Hu MC Am. J. Physiol. Renal Physiol. 2018 04 314 4 F501-F516 Dynamic Change of Transcription Pausing through Modulating NELF Protein Stability Regulates Granulocytic Differentiation. Liu X, Gogate AA, Tastemel M, Malladi VS, Yao H, Nguyen K, Huang LJ, Bai X Blood Adv 2017 Aug 1 18 1358-1367 Activating JAK2 mutants reveal cytokine receptor coupling differences that impact outcomes in myeloproliferative neoplasm. Yao H, Ma Y, Hong Z, Zhao L, Monaghan SA, Hu MC, Huang LJ Leukemia 2017 Jan Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation. Lu Z, Xie J, Wu G, Shen J, Collins R, Chen W, Kang X, Luo M, Zou Y, Huang LJ, Amatruda JF, Slone T, Winick N, Scherer PE, Zhang CC Nat. Med. 2016 Dec Uncoupling JAK2 V617F activation from cytokine-induced signalling by modulation of JH2 aC helix. Leroy E, Dusa A, Colau D, Motamedi A, Cahu X, Mouton C, Huang LJ, Shiau AK, Constantinescu SN Biochem. J. 2016 06 473 11 1579-91 Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2. Dutchak PA, Laxman S, Estill SJ, Wang C, Wang Y, Wang Y, Bulut GB, Gao J, Huang LJ, Tu BP Cell Rep 2015 Jul 12 3 371-9 Genome Editing of Mouse Fibroblasts by Homologous Recombination for Sustained Secretion of PDGF-B and Augmentation of Wound Healing Barker, J. C., Barker, A. D., Bills, J., Huang, J., Wight-Carter, M., Delgado, I., Noble, D. L., Huang, L. J., Porteus, M. H., and Davis, K. E. Plast Reconstr Surg 2014 3 134 389e-401e Results 1-10 of 27 1 2 3 Next Last Honors & Awards American Cancer Society Postdoctoral Fellowship (2002) Howard Temin Award (2002) NIH NRSA Award (1998) Professional Associations/Affiliations American Society of Biochemistry and Molecular Biology (2006) American Society of Hematology (2007)
