Medical School
Duke University School of Medicine (1979)
University of California at San Francisco (1980), Internal Medicine
University of California at San Francisco (1983), Internal Medicine
University of California at San Francisco (1985), Gastroenterology

Research Interest

  • Biliary secretion
  • Cellular mechanisms of insulin resistance
  • Epithelial ion channels
  • Purinergic signaling


Featured Publications LegendFeatured Publications

Volume-sensitive tyrosine kinases regulate liver cell volume through effects on vesicular trafficking and membrane Na+ permeability.
Feranchak AP, Kilic G, Wojtaszek PA, Qadri I, Fitz JG J. Biol. Chem. 2003 Nov 278 45 44632-8
Cholangiocytes exhibit dynamic, actin-dependent apical membrane turnover.
Doctor RB, Dahl R, Fouassier L, Kilic G, Fitz JG Am. J. Physiol., Cell Physiol. 2002 May 282 5 C1042-52
Heterotrimeric G-proteins activate Cl- channels through stimulation of a cyclooxygenase-dependent pathway in a model liver cell line.
Kilic G, Fitz JG J. Biol. Chem. 2002 Apr 277 14 11721-7
Cystic fibrosis transmembrane conductance regulator facilitates ATP release by stimulating a separate ATP release channel for autocrine control of cell volume regulation.
Braunstein GM, Roman RM, Clancy JP, Kudlow BA, Taylor AL, Shylonsky VG, Jovov B, Peter K, Jilling T, Ismailov II, Benos DJ, Schwiebert LM, Fitz JG, Schwiebert EM J. Biol. Chem. 2001 Mar 276 9 6621-30
ClC-2 chloride channels contribute to HTC cell volume homeostasis.
Roman RM, Smith RL, Feranchak AP, Clayton GH, Doctor RB, Fitz JG Am. J. Physiol. Gastrointest. Liver Physiol. 2001 Mar 280 3 G344-53

Honors & Awards

  • MERIT Award
    National Institutes of Health (2002)
  • Association of American Physicians
  • Waterman Chair in Liver Research
  • Eugene Stead Award for Excellence in Teaching
    Duke University (1991)
  • American Society for Clinical Investigation
    Best Doctors in America 2001, 2002, 2003 (0)

Professional Associations/Affiliations

  • American Association for the Study of Liver Disease
  • American Federation for Clinical Research
  • American Gastroenterological Association
  • American Society for Clinical Investigation
  • Association of American Physicians