University of Calcutta - India (1988), Chemistry
Graduate School
University of Calcutta - India (1991), Biochemistry
Graduate School
Uni of Nebraska-Lincoln (1997), Chemistry

Research Interest

  • Role of Cycloxygenase-2 in radiation and chemo-resistance.
  • Role of small molecule inhibitors as radio-sensitizers


Featured Publications LegendFeatured Publications

The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry.
Lee KJ, Shang ZF, Lin YF, Sun J, Morotomi-Yano K, Saha D, Chen BP Neoplasia 2015 Apr 17 4 329-38
NSCLC cells demonstrate differential mode of cell death in response to the combined treatment of radiation and a DNA-PKcs inhibitor.
Yu L, Shang ZF, Hsu FM, Zhang Z, Tumati V, Lin YF, Chen BP, Saha D Oncotarget 2015 Jan
Reciprocal regulation of hypoxia-inducible factor 2a and GLI1 expression associated with the radioresistance of renal cell carcinoma.
Zhou J, Wu K, Gao D, Zhu G, Wu D, Wang X, Chen Y, Du Y, Song W, Ma Z, Authement C, Saha D, Hsieh JT, He D Int. J. Radiat. Oncol. Biol. Phys. 2014 Nov 90 4 942-51
Polymeric nanoparticles for targeted radiosensitization of prostate cancer cells.
Menon JU, Tumati V, Hsieh JT, Nguyen KT, Saha D J Biomed Mater Res A 2014 Aug
Sensitization of radio-resistant prostate cancer cells with a unique cytolethal distending toxin.
Lai CH, Chang CS, Liu HH, Tsai YS, Hsu FM, Yu YL, Lai CK, Gandee L, Pong RC, Hsu HW, Yu L, Saha D, Hsieh JT Oncotarget 2014 Jun
DOC-2/DAB2 Interacting Protein Status in High-Risk Prostate Cancer Correlates With Outcome for Patients Treated With Radiation Therapy.
Jacobs C, Tumati V, Kapur P, Yan J, Hong D, Bhuiyan M, Xie XJ, Pistenmaa D, Yu L, Hsieh JT, Saha D, Kim DW Int. J. Radiat. Oncol. Biol. Phys. 2014 May
EGFR wild type antagonizes EGFRvIII-mediated activation of Met in glioblastoma.
Li L, Puliyappadamba VT, Chakraborty S, Rehman A, Vemireddy V, Saha D, Souza RF, Hatanpaa KJ, Koduru P, Burma S, Boothman DA, Habib AA Oncogene 2013 Dec
An EGFR wild type-EGFRvIII-HB-EGF feed-forward loop regulates the activation of EGFRvIII.
Li L, Chakraborty S, Yang CR, Hatanpaa KJ, Cipher DJ, Puliyappadamba VT, Rehman A, Jiwani AJ, Mickey B, Madden C, Raisanen J, Burma S, Saha D, Wang Z, Pingle SC, Kesari S, Boothman DA, Habib AA Oncogene 2013 Sep
Role of p53, Bax, p21, and DNA-PKcs in radiation sensitivity of HCT-116 cells and xenografts.
Huerta S, Gao X, Dineen S, Kapur P, Saha D, Meyer J Surgery 2013 Aug 154 2 143-51
Development of a locally advanced orthotopic prostate tumor model in rats for assessment of combined modality therapy.
Tumati V, Mathur S, Song K, Hsieh JT, Zhao D, Takahashi M, Dobin T, Gandee L, Solberg TD, Habib AA, Saha D Int. J. Oncol. 2013 Mar