Rodney E. Infante obtained his MD, PhD in 2012 from the University of Texas Southwestern Medical School where he studied intracellular lipid trafficking under the tutelage of Drs. Michael Brown and Joseph Goldstein.  After completing clinical training in internal medicine at Massachusetts General Hospital, he returned to UT Southwestern for a fellowship in gastroenterology and hepatology.  He has now joined the faculty in the Center for Human Nutrition with secondary appointments in the Department of Molecular Genetics and the Department of Internal Medicine.  His lab is interested in the molecules and mechanisms that cause cachexia-associated adipose wasting associated with oncologic, liver, infectious, and rheumatologic diseases. By understanding the mechanisms that underlie adipose loss in cachexia, his lab plans to identify new treatments for cachexia patients while also providing insights to induce adipose loss in obesity.


Medical School
UT Southwestern Medical School (2012)
Massachusetts General Hospital (2014), Internal Medicine
UT Southwestern Medical Center (2017), Gastroenterology

Research Interest

  • Cachexia
  • Cytokine-Associated Adipocyte Lipolysis
  • Lipid Metabolsim
  • Obesity


Featured Publications LegendFeatured Publications

Rich NE, Iyengar P, Infante RE, Singal AG, Clin Gastroenterol Hepatol 2022 Feb
Associations of Prior Chronic Use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Glucocorticoids With Cachexia Incidence and Survival.
Olaechea S, Gilmore A, Alvarez C, Gannavarapu BS, Infante R, Iyengar P, Front Oncol 2022 12 922418
Cytokine-Mediated STAT3 Transcription Supports ATGL/CGI-58-Dependent Adipocyte Lipolysis in Cancer Cachexia.
Gandhi AY, Yu J, Gupta A, Guo T, Iyengar P, Infante RE, Front Oncol 2022 12 841758
Primary Tumor Fluorine-18 Fluorodeoxydglucose (18F-FDG) Is Associated With Cancer-Associated Weight Loss in Non-Small Cell Lung Cancer (NSCLC) and Portends Worse Survival.
Olaechea S, Gannavarapu BS, Alvarez C, Gilmore A, Sarver B, Xie D, Infante R, Iyengar P, Front Oncol 2022 12 900712
The influence of tumour fluorodeoxyglucose avidity and cachexia development on patient survival in oesophageal or gastroesophageal junction cancer.
Olaechea S, Gannavarapu BS, Gilmore A, Alvarez C, Iyengar P, Infante R, JCSM Clin Rep 2021 Oct 6 4 128-136
Cachexia is Prevalent in Patients with Hepatocellular Carcinoma and Associated with Worse Prognosis.
Rich NE, Phen S, Desai N, Mittal S, Yopp AC, Yang JD, Marrero JA, Iyengar P, Infante RE, Singal AG, Clin Gastroenterol Hepatol 2021 Sep

Honors & Awards

  • AGA Research Scholar Award
  • Burroughs Wellcome Career Award for Medical Scientists
  • UTSW President's Research Council Award
  • V Foundation Scholar Award
  • UTSW Hemphill-Gojer Award in Internal Medicine
  • ASCB Norton B. Gilula Award
  • UTSW Nominata Award