Biography

1985 Xiamen University, Xiamen, China, BS, Biology

1996 State University of New York, Albany, NY, PhD, Neuroscience

2003 The Salk Institute, La Jolla, CA, Research Associate

Education
Undergraduate
Xiamen University - China , Biology
Graduate School
SUNY at Albany (1996)

Research Interest
  • Neurodegeneration
  • Synapse Formation

Publications

Featured Publications LegendFeatured Publications

Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors.
Fujun Chen, Yun Liu, Yoshie Sugiura, Paul D. Allen, Ronald G. Gregg and Weichun Lin Nature Neuroscience March 2011
Ubiquitin carboxyl-terminal hydrolase L1 is required for maintaining the structure and function of the neuromuscular junction.
Fujun Chen, Yoshie Sugiura, Kalisa Galina Myers, Yun Liu, and Weichun Lin Proceedings of the National Academy of Sciences, U.S.A January 2010 107 1636-1641
Essential roles of acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning
Yun Liu, Daniel Padgett, Masazumi Takahashi, Hongqiao Li, Ayaz Sayeed, Russell W. Teichert, Baldomero M. Olivera, Joseph McArdle, William N. Green, and Weichun Lin Development June 2008 135 1957-1967
Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism.
Weichun Lin, Bertha Dominguez, Jiefei Yang, Prafulla Aryal, Eugene P. Brandon, Fred H. Gage and Kuo-Fen Lee Neuron 2005 46 569-579
Distinct roles of nerve and muscle in postsynaptic differentiation of the neuromuscular synapse.
Weichun Lin, Robert Burgess, Bertha Dominguez, Samuel Pfaff, Joshua Sanes and Kuo-Fen Lee Nature March 2001 410 1057-1064
Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors.
Fujun Chen, Yun Liu, Yoshie Sugiura, Paul D. Allen, Ronald G. Gregg and Weichun Lin Nature Neuroscience March 2011
The role of Synaptobrevin1/VAMP1 in Ca2+-triggered neurotransmitter release at the mouse neuromuscular junction.
Yun Liu, Yoshie Sugiura and Weichun Lin Journal of Physiology 2011 589 1603-1618
Ubiquitin carboxyl-terminal hydrolase L1 is required for maintaining the structure and function of the neuromuscular junction.
Fujun Chen, Yoshie Sugiura, Kalisa Galina Myers, Yun Liu, and Weichun Lin Proceedings of the National Academy of Sciences, U.S.A January 2010 107 1636-1641
Abnormal development of the neuromuscular junction in Nedd4-deficient mice.
Yun Liu, Oppenheim, R. W., Sugiura, Y., and Weichun Lin Developmental Biology June 2009 330 153-166
Essential roles of acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning
Yun Liu, Daniel Padgett, Masazumi Takahashi, Hongqiao Li, Ayaz Sayeed, Russell W. Teichert, Baldomero M. Olivera, Joseph McArdle, William N. Green, and Weichun Lin Development June 2008 135 1957-1967

Honors & Awards
  • Mallinckrodt Scholar
    Edward Mallinckrodt, Jr. Foundation (2006)
  • Effie Marie Cain Scholar in Medical Research
    U.T. Southwestern Endowed Scholar Award, 2003-2007 (2003)
  • Postdoctoral Fellowship
    Le Ducq Foundation (2000)