Joachim Seemann, Ph.D.

UT Southwestern Medical Center, Department of Cell Biology
Associate Professor (2011-present)

UT Southwestern Medical Center, Department of Cell Biology
Assistant Professor (2003-2011)

Yale School of Medicine, New Haven, CT
Postdoctoral Fellow (2000-2003)

Cancer Research UK London Research Institute, United Kingdom
Postdoctoral Fellow (1997-1999)

Max-Planck-Institute for Biophysical Chemistry Göttingen, Germany
Graduate Student, PhD (1993-1996)

University of Stuttgart, Germany
Diploma in Biology (1993)

Graduate School

Max Planck Inst for Biophysica (1996), Biophysical Chemistry

• Golgi and organelle biogenesis
• Membrane traffic
• Migration of cells
• Mitosis

Featured Publications

GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules.

Wei JH, Zhang ZC, Wynn RM, Seemann J Cell 2015 Jul 162 2 287-99

The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase.

Schumacher MM, Elsabrouty R, Seemann J, Jo Y, DeBose-Boyd RA Elife 2015 4

Point Mutation in Luminal Loop 7 of Scap Blocks Interaction with Loop 1 and Abolishes Movement to Golgi.

Zhang Y, Motamed M, Seemann J, Brown MS, Goldstein JL J. Biol. Chem. 2013 Apr

Modular organization of the mammalian Golgi apparatus.

Nakamura N, Wei JH, Seemann J Curr. Opin. Cell Biol. 2012 Aug 24 4 467-74

Golgi Biogenesis.

Wang Y, Seemann J Cold Spring Harbor perspectives in biology 2011 Jun

Nakiterpiosin targets tubulin and triggers mitotic catastrophe in human cancer cells.

Wei JH, Seemann J Mol. Cancer Ther. 2010 Dec 9 12 3375-85

The mitotic spindle mediates inheritance of the Golgi ribbon structure.

Wei JH, Seemann J J. Cell Biol. 2009 Feb 184 3 391-7

Induction of asymmetrical cell division to analyze spindle-dependent organelle partitioning using correlative microscopy techniques

Wei JH, Seemann J Nature Prot 2009 4 1653-1662

Spatial separation of Golgi and ER during mitosis protects SREBP from unregulated activation

Bartz R, Sun LP, Bisel B, Wei JH, Seemann J EMBO J 2008 27 948-955

ERK regulates Golgi and centrosome orientation towards the leading edge through GRASP65

Bisel B, Wang Y, Wei JH, Xiang Y, Tang D, Miron-Mendoza M, Yoshimura S, Nakamura N, Seemann J The Journal of Cell Biology 2008 182 837-843

• Virginia Murchison Lithicum Scholar in Medical Research
  UT Southwestern Endowed Scholar (2003)
• Imperial Cancer Research Fund
  Postdoctoral Fellowship (1999)
• German Research Foundation
  Postdoctoral Fellowship (1997)
• Max Planck Society
  Graduate Fellowship (1994)