
Joachim Seemann, Ph.D.
Associate Professor
Endowed Title Virginia Murchison Linthicum Scholar in Medical Research
School Medical School
Department Cell Biology
Graduate Programs Cancer Biology, Cell and Molecular Biology
Biography
UT Southwestern Medical Center, Department of Cell Biology
Associate Professor (2011-present)
UT Southwestern Medical Center, Department of Cell Biology
Assistant Professor (2003-2011)
Yale School of Medicine, New Haven, CT
Postdoctoral Fellow (2000-2003)
Cancer Research UK London Research Institute, United Kingdom
Postdoctoral Fellow (1997-1999)
Max-Planck-Institute for Biophysical Chemistry Göttingen, Germany
Graduate Student, PhD (1993-1996)
University of Stuttgart, Germany
Diploma in Biology (1993)
Education
- Graduate School
- Max Planck Inst for Biophysica (1996), Biophysical Chemistry
Research Interest
- Golgi and organelle biogenesis
- Membrane traffic
- Migration of cells
- Mitosis
Publications
Featured Publications
- GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules.
- Wei JH, Zhang ZC, Wynn RM, Seemann J Cell 2015 Jul 162 2 287-99
- The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase.
- Schumacher MM, Elsabrouty R, Seemann J, Jo Y, DeBose-Boyd RA Elife 2015 4
- Point Mutation in Luminal Loop 7 of Scap Blocks Interaction with Loop 1 and Abolishes Movement to Golgi.
- Zhang Y, Motamed M, Seemann J, Brown MS, Goldstein JL J. Biol. Chem. 2013 Apr
- Modular organization of the mammalian Golgi apparatus.
- Nakamura N, Wei JH, Seemann J Curr. Opin. Cell Biol. 2012 Aug 24 4 467-74
- Golgi Biogenesis.
- Wang Y, Seemann J Cold Spring Harbor perspectives in biology 2011 Jun
- Nakiterpiosin targets tubulin and triggers mitotic catastrophe in human cancer cells.
- Wei JH, Seemann J Mol. Cancer Ther. 2010 Dec 9 12 3375-85
- The mitotic spindle mediates inheritance of the Golgi ribbon structure.
- Wei JH, Seemann J J. Cell Biol. 2009 Feb 184 3 391-7
- Induction of asymmetrical cell division to analyze spindle-dependent organelle partitioning using correlative microscopy techniques
- Wei JH, Seemann J Nature Prot 2009 4 1653-1662
- Spatial separation of Golgi and ER during mitosis protects SREBP from unregulated activation
- Bartz R, Sun LP, Bisel B, Wei JH, Seemann J EMBO J 2008 27 948-955
- ERK regulates Golgi and centrosome orientation towards the leading edge through GRASP65
- Bisel B, Wang Y, Wei JH, Xiang Y, Tang D, Miron-Mendoza M, Yoshimura S, Nakamura N, Seemann J The Journal of Cell Biology 2008 182 837-843
Honors & Awards
- Virginia Murchison Lithicum Scholar in Medical Research
UT Southwestern Endowed Scholar (2003) - Imperial Cancer Research Fund
Postdoctoral Fellowship (1999) - German Research Foundation
Postdoctoral Fellowship (1997) - Max Planck Society
Graduate Fellowship (1994)