Education
Undergraduate
University of London - England (1982)
Graduate School
University of London - England (1993)

Research Interest
  • Expressed and Native Protein Lligation
  • Mass Spectrometry
  • Peptide Chemistry
  • Protein Identification by Mass Spectrometry
  • Protein Sequencing

Publications

Featured Publications LegendFeatured Publications

Yersinia YopJ acetylates critical Ser/Thr residues on MKKs and IKKb blocking the innate immune response
38. Mukherjee, S., Keitany, G., Wang, Y., Li, Y., Ball, H. L., Goldsmith, E. J. and Orth, K. Science 2006 312 1211-1214
Nicastrin functions as a gamma-secretase substrate receptor.
36. Shah, S., Lee, S. F., Tabuchi, K., Hao, Y. H., Yu, C., LaPlant, Q., Ball, H., Dann, C. E., Sudhof, T. and Yu, G Cell 2005 122 435-447
Engineering the prion protein using chemical synthesis.
Ball, H.L., King, D., Cohen, F.E., Prusiner, S.B., and Baldwin, M.A. J. Peptide Res. 2001 58 357-388
A synthethic peptide causes prion disease in transgenic mice.
Kaneko, K., Ball, H.L., Willie, H, Zhang, H., Groth, D., Torchias M., Tremblay, P., Safar, J., Prusiner, S.B., DeArmond, S.J., Baldwin, M.A., and Cohen, F.E. J. Biol. Chem. 2000 295 997-1007
Chemical protein synthesis and purification: A methodology.
Ball, H.L., and Mascagni, P. Int. J. Peptide Protein Res. 1996 48 31-47
AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling
Yarbrough ML, Li Y, Kinch LN, Grishin NV, Ball HL, Orth K Science January 2009 323(5911) 269-72
Post-translational modifications corresponding to 42 Da ? Study of acetylation on Ser/Thr/Tyr/Lys and trimethylation on Lys using electrospray tandem mass spectrometry
Li, Y and Ball H.L. Int. J. of mass Spectrometry 2009 281 24-30
Novel reversible biotinylated probe for the selective enrichment of phosphorylated peptides from complex mixtures
Jalili PR, Ball HL J Am Soc Mass Spectrom May 2008 19(5) 741-50
Reversible biotinylated probe for the selective enrichment of phosphopeptides from complex biological mixtures.?
Jalili P.R. and Ball, H.L. J. Am. Soc. Mass Spectrom. 2008 19 741-750
Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice.
Safar, J.G., Scott, M., Monaghan, J., Deering, C., Didorenko, S., Vergara, J., Ball, H.L., Legname, G., Leclerc, E., Solforosi, L., Serban, H., Groth, D., Burton, D.R., Prusiner, S.B. and Williamson, R.A. Nat. Biotechnol. 2002 20 1147-1150

Professional Associations/Affiliations
  • American Peptide Society
  • American Society for Mass Spectrometry