- Univ of California-Berkeley (1997), Molecular & Cell Biology
- Univ of California-Berkeley (1997), Bioengineering
- Graduate School
- Stanford University (2002), Biophysics
- How cells control their cholesterol levels
- Ostreolysin A and anthrolysin O use different mechanisms to control movement of cholesterol from the plasma membrane to the endoplasmic reticulum.
- Johnson KA, Endapally S, Vazquez DC, Infante RE, Radhakrishnan A, J. Biol. Chem. 2019 Oct
- Cholesterol accessibility at the ciliary membrane controls Hedgehog signaling.
- Kinnebrew M, Iverson EJ, Patel BB, Pusapati GV, Kong JH, Johnson KA, Luchetti G, Eckert KM, McDonald JG, Covey DF, Siebold C, Radhakrishnan A, Rohatgi R, Elife 2019 Oct 8
- Molecular Discrimination between Two Conformations of Sphingomyelin in Plasma Membranes.
- Endapally S, Frias D, Grzemska M, Gay A, Tomchick DR, Radhakrishnan A Cell 2019 Jan
- Monitoring and Modulating Intracellular Cholesterol Trafficking Using ALOD4, a Cholesterol-Binding Protein.
- Endapally S, Infante RE, Radhakrishnan A Methods Mol. Biol. 2019 1949 153-163
- Retrospective on Cholesterol Homeostasis: The Central Role of Scap
- Brown MS, Radhakrishnan A, Goldstein JL Annu Rev Biochem. 2018 Jun 87 783-807
- Continuous transport of a small fraction of plasma membrane cholesterol to endoplasmic reticulum regulates total cellular cholesterol.
- Infante RE, Radhakrishnan A Elife 2017 Apr 6
- Cholesterol-induced conformation changes in the sterol-sensing domain of the scap protein suggest feedback mechanism to control cholesterol synthesis.
- Gao Y, Zhou Y, Goldstein JL, Brown MS, Radhakrishnan A J. Biol. Chem. 2017 Apr
- Variability of cholesterol accessibility in human red blood cells measured using a bacterial cholesterol-binding toxin.
- Chakrabarti RS, Ingham SA, Kozlitina J, Gay A, Cohen JC, Radhakrishnan A, Hobbs HH Elife 2017 Feb 6
- Direct Demonstration that Loop1 of Scap Binds to Loop7, a crucial event in cholesterol homeostasis.
- Zhang Y, Lee KM, Kinch LN, Clark L, Grishin NV, Rosenbaum DM, Brown MS, Goldstein JL, Radhakrishnan A J. Biol. Chem. 2016 Apr
- PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels.
- Ren R, Zhou X, He Y, Ke M, Wu J, Liu X, Yan C, Wu Y, Gong X, Lei X, Yan SF, Radhakrishnan A, Yan N Science 2015 Jul 349 6244 187-91