Tao Yue, Ph.D.

Undergraduate

Unlisted - International Colle (1999), Biology

Graduate School

Univ of Tx Southwestern Med Ct (2011), Philosophy

• Ectopic bone formation, osteosarcoma and tumor Immunology
• T cell-mediated Immunity
• Wound healing and trauma Immunology

 Featured Publications

SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell-mediated immunity.

Yue T, Zhan X, Zhang D, Jain R, Wang KW, Choi JH, Misawa T, Su L, Quan J, Hildebrand S, Xu D, Li X, Turer E, Sun L, Moresco EMY, Beutler B, Science 2021 05 372 6543

Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40.

Zhang D, Yue T, Choi JH, Nair-Gill E, Zhong X, Wang KW, Zhan X, Li X, Choi M, Tang M, Quan J, Hildebrand S, Moresco EMY, Beutler B, Nat. Immunol. 2019 Aug

The cell adhesion molecule echinoid functions as a tumor suppressor and upstream regulator of the Hippo signaling pathway.

Yue T, Tian A, Jiang J Dev. Cell 2012 Feb 22 2 255-67

A critical role for dorsal progenitors in cortical myelination.

Yue T, Xian K, Hurlock E, Xin M, Kernie SG, Parada LF, Lu QR J. Neurosci. 2006 Jan 26 4 1275-80

Myelinogenesis and axonal recognition by oligodendrocytes in brain are uncoupled in Olig1-null mice.

Xin M, Yue T, Ma Z, Wu FF, Gow A, Lu QR J. Neurosci. 2005 Feb 25 6 1354-65

Targeting tumor microenvironment with antibody-guided IL-2 pro-cytokine promotes and rejuvenates dysfunctional CD8⁺ T cells.

Wang X, Liu L, Yue T, Sun Z, Bae J, Tseng KF, Zhang A, Qiao J, Fu YX, Signal Transduct Target Ther 2023 Jul 8 1 268

Sulfatides are endogenous ligands for the TLR4-MD-2 complex.

Su L, Athamna M, Wang Y, Wang J, Freudenberg M, Yue T, Wang J, Moresco EMY, He H, Zor T, Beutler B, Proc Natl Acad Sci U S A 2021 07 118 30

Thousands of induced germline mutations affecting immune cells identified by automated meiotic mapping coupled with machine learning.

Xu D, Lyon S, Bu CH, Hildebrand S, Choi JH, Zhong X, Liu A, Turer EE, Zhang Z, Russell J, Ludwig S, Mahrt E, Nair-Gill E, Shi H, Wang Y, Zhang D, Yue T, Wang KW, SoRelle JA, Su L, Misawa T, McAlpine W, Sun L, Wang J, Zhan X, Choi M, Farokhnia R, Sakla A, Schneider S, Coco H, Coolbaugh G, Hayse B, Mazal S, Medler D, Nguyen B, Rodriguez E, Wadley A, Tang M, Li X, Anderton P, Keller K, Press A, Scott L, Quan J, Cooper S, Collie T, Qin B, Cardin J, Simpson R, Tadesse M, Sun Q, Wise CA, Rios JJ, Moresco EMY, Beutler B, Proc Natl Acad Sci U S A 2021 07 118 28

Dominant atopy risk mutations identified by mouse forward genetic analysis.

SoRelle JA, Chen Z, Wang J, Yue T, Choi JH, Wang KW, Zhong X, Hildebrand S, Russell J, Scott L, Xu D, Zhan X, Bu CH, Wang T, Choi M, Tang M, Ludwig S, Zhan X, Li X, Moresco EMY, Beutler B, Allergy 2021 04 76 4 1095-1108

Mutual inhibition between Prkd2 and Bcl6 controls T follicular helper cell differentiation.

Misawa T, SoRelle JA, Choi JH, Yue T, Wang KW, McAlpine W, Wang J, Liu A, Tabeta K, Turer EE, Evers B, Nair-Gill E, Poddar S, Su L, Ou F, Yu L, Russell J, Ludwig S, Zhan X, Hildebrand S, Li X, Tang M, Murray AR, Moresco EMY, Beutler B, Sci Immunol 2020 Jan 5 43

• Rally Foundation Cancer Career Development Award
  

• American Association for Cancer Research
• Simmons Comprehensive Cancer Center
• Society for Immunotherapy of Cancer