Heidi Jacobe, M.D. Titles and Appointments Professor Endowed Title James N. Gilliam, M.D. Chair in Dermatology Schools Medical School Departments Dermatology | Medical School Dean's Office | Public Health You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Dr. Heidi T. Jacobe is a Professor of Dermatology at UT Southwestern Medical Center and a Professor in the Peter O’Donnell Jr. School of Public Health. She serves as Associate Dean of Clinical Research Development and as Director of the Master of Science in Clinical Investigation, where she leads institutional programs to advance the development of clinician‑scientists and the clinical research workforce. Dr. Jacobe’s research focuses on sclerosing skin diseases, including morphea and systemic sclerosis, with an emphasis on disease outcomes, biomarkers, and clinical trials. She has led and collaborated on investigator‑initiated, NIH, philanthropy, industry, and Department of Defense‑funded studies aimed at improving disease measurement, understanding disease heterogeneity, and advancing evidence‑based care for patients with complex inflammatory and fibrosing skin disorders. Congruent with her research, Dr. Jacobe is a clinical expert in the diagnosis and care of patients with sclerosing skin disorders and see patients referred from specialists from around the world. Dr Jacobe's contributions to the field have been acknowledged by the receipt of two endowments including the Jame N. Gilliam Chair in Rheumatology-Dermatology and the DJ Moody Family Fund for Scleroderma Research. In addition to her research program, Dr. Jacobe holds leadership roles within UT Southwestern’s NIH Clinical and Translational Science Award (CTSA) program, where she serves as Director of the Clinical and Translational Science Workforce Development Core and as Co‑Director and MPI of the NIH KL2 Clinical Scholars Program. Through these roles, she has developed and implemented institutional training programs that support early‑career investigators across disciplines. Dr. Jacobe is a Distinguished Teaching Professor and a member of the UT Southwestern Promotion and Tenure Committee. She is also a trained facilitator in the Center for the Improvement of Mentored Experiences in Research (CIMER) Entering Mentoring curriculum and certified executive coach, reflecting her commitment to mentorship, leadership development, and academic career advancement. She received her medical degree with honors from Baylor College of Medicine, completed her dermatology residency at UT Southwestern—serving as Chief Resident—and earned a Master of Science in Clinical Science with distinction through the UT Southwestern Clinical Scholars Program. Education Medical School Baylor College of Medicine (1996) Internship Baylor College of Medicine (1997), Internal Medicine Residency UT Southwestern Medical Center (2000), Dermatology Other Post Graduate Training UT Southwestern Medical School (2008) Graduate School UT Southwestern Medical School (2008), Clinical Science Research Interest Morphea/localized Scleroderma Phototherapy Scleroderma UVAI Phototherapy Publications Validation of CXCL9 as a biomarker of morphoea disease state and severity through longitudinal analysis Chen HW, Barber G, Foster J, Zigler CK, O'Brien JC, Jacobe HT British Journal of Dermatology 2025 Dec 193 1174-1181 Localized scleroderma: multiparametric MRI with diffusion-weighted imaging and gadolinium-based perfusion imaging for assessing disease activity Iancau A, Attia S, Sarlashkar P, Cepica T, Duarte Silva F, Eajazi A, Xi Y, Jacobe H, Chhabra A Skeletal radiology 2025 Dec 54 2695-2704 Localized scleroderma: anatomic MRI findings of morphea with inter-reader analysis Iancau A, Attia S, Duarte Silva F, Eajazi A, Malja E, Xi Y, Jacobe H, Chhabra A Skeletal radiology 2025 Oct 54 2055-2065 Group coaching for career development: Supporting the endangered early career researcher Palmer L, Wadhwa A, Matulevicius S, Rohatgi A, Jacobe HT Journal of Clinical and Translational Science 2025 Jul 9 Unique and shared transcriptomic signatures underlying localized scleroderma pathogenesis identified using interpretable machine learning Rosen AB, Sanyal A, Hutchins T, Werner G, Berkowitz JS, Tabib T, Lafyatis R, Jacobe H, Das J, Torok KS JCI Insight 2025 Apr 10 Oregon primary care providers as a frontline defense in the War on Melanoma™: improving access to melanoma education Becker AL, Nelson JH, Verdieck-Devlaeminck A, Berry EG, Orfaly VE, Stoos ER, Tran J, Latour E, Sahni VN, Xu S, Babcock M, Bar A, Becevic M, Chan C, Chisholm D, Diehl K, Edison K, Ferris LK, Foltz EA, Geller AC, Jacobe H, Johnson MM, Kinghorn P, Leitenberger J, Ludzik J, McClanahan D, Mengden-Koon S, Nelson K, Petering R, Prasad S, Roscher A, Savory S, Smith EH, Swetter SM, Tofte S, Weinstock MA, White K, Wisco O, Witkowski A, Leachman SA Frontiers in Medicine 2025 12 Completion of a standardizable competency-based research training program improves understanding and preparedness for both new and experienced clinical research professionals Palmer L, Morones SE, Jacobe HT, Oilepo R Journal of Clinical and Translational Science 2024 Dec 9 The skinny on skin: The role of skin-aware professionals in skin cancer surveillance Diehl K, Nelson J, Haddadin O, Stoos E, Shafer A, Mason A, Girard D, Malcolm T, Geller AC, Latour E, Bailey E, Young JN, Zhao H, Gillespie J, Pfeifer H, Lee C, Shea M, DeCampos-Stairiker M, Smith J, Becker A, Bash GN, Sahni V, Fan Y, Munoz EP, Baron D, Popovici N, Orfaly VE, Baghoomian W, Foltz E, Kahlen K, Savory S, Jacobe H, Leachman SA Journal of Cosmetic Dermatology 2024 Dec 23 4173-4201 Incidence and Prevalence of Morphea Keum H, Chen HW, Haley RW, Jacobe HT JAMA Dermatology 2024 Oct 160 1128-1130 Characterization of Endothelial Cell Subclusters in Localized Scleroderma Skin with Single-Cell RNA Sequencing Identifies NOTCH Signaling Pathway Hutchins T, Sanyal A, Esencan D, Lafyatis R, Jacobe H, Torok KS International journal of molecular sciences 2024 Oct 25 Results 1-10 of 108 1 2 3 4 5 Next Last Books Featured Books Dermatopathology of Connective Tissue Diseases. In Advances in Dermatology Costner MI, Jacobe H (2000). St. Louis, MO, Harcourt Alopecia. In Netter Textbook of Internal Medicine Jacobe H, Rubenstein DS (2001). New York, NY, Icon Pediculosis and scabies. In Netter Textbook of Internal Medicine Jacobe H (2001). New York, NY, Icon Netter Textbook of Internal Medicine. In Psoriasis Jacobe H (2001). New York, NY, Icon Antoantibodies encountered in patients with autoimmune connective tissue diseases. In Dermatology Jacobe H, Sontheimer RD (2003). London, England, Mosby Sunburn. In Conn's Current Therapy Jacobe H (2005). Philadelphia, PA, Elsevier Autoantibodies encountered in patients with autoimmune connective tissue diseases. In Dermatology Jacobe H, Sontheimer RD (2008). London, England, Elsevier Psoriasis. In Netter Textbook of Internal Medicine Jacobe HT, Parsons DJ, Rubenstein DS (2008). London, England, Elsevier, Ltd Photoimmunology. In Clinical Immunodermatology Hansen C, Leitenberger JJ, Jacobe HT, Cruz PD Jr (2009). Germany, Springer Verlag Ultraviolet phototherapy and the management of atopic dermatitis. In Atopic Dermatitis Vandergriff T, Jacobe H (2009). New York, NY, Informa Healthcare Autoantibodies encountered in patients with autoimmune connective tissue disease. In Dermatology Jacobe H, Sontheimer R, Saxton-Daniels S. (2012). London, England, Elsevier, Ltd Morphea. In Treatment of Skin Disease O'Brien J, Jacobe H. (2016). London, UK, Elsevier Morphea and lichen sclerosis. In Fitzpatrick's Dermatology Cyrus N, Jacobe H (2017). New York, NY, McGraw-Hill Morphea. In Dermatology in General Medicine Jacobe H, Saxton-Daniels S. (2012). New York, NY, McGraw-Hill Morphea. In Treatment of Skin Disease Garza R, Jacobe H (2014). London, England, Elsevier Localized scleroderma. In Visual Guide to Scleroderma and Approach to Treatment Bangert C, Kim A, Jacobe H (2014). New York, NY, Springer Scleroderma and morphea. In Atlas of Skin of Color Baker LA, Jacobe HT. (2014). Berlin/Heidelberg, Germany, Springer-Verlag Localized forms of scleroderma in adults. In Scleroderma - From Pathogenesis to Comprehensive Management Teske N, Jacobe H (2015). New York, NY, Springer Honors & Awards D Magazine Best Doctor (2020-2022) D Magazine Best Doctor (2018) Society for Investigative DermatologyExecutive Board (2017-2018) Photomedicine SocietyPresident (2015-2018) Best Doctors in America (2012-2016) Faculty of 1000Reviewer (2012-2016) Who's Who in America (2010-2016) North American Rheumatologic Disorders of the Skin Committee MemberMedical Dermatology Society (2008) Phototherapy Task Force MemberNational Psoriasis Foundation (2008) Secretary-TreasurerPhotomedicine Society (2008-2015) Skin Cancer FoundationPhotobiology Committee (2007-2017) Deans ScholarClinical Scholars Program candidate for Master in Clinical Science with Distinction (2006) Teacher of the YearVoted on by the residents in Dermatology (2004) University of Texas Plan II Honors Program, Austin, TXGraduate with Special Honors (1992) Professional Associations/Affiliations American Academy of Dermatology (2010) American Medical Association (2000) Childhood Arthritis & Rheumatology Research Alliance (CARRA) (2010) Dallas Dermatologic Society (2002) Dermatology Foundation (2013) Dermatology Teachers Exchange Group (2000) National Psoriasis Foundation (2008) Pediatric Dermatology Research Alliance (PeDRA) (2016) Photomedicine Society (2005) Rheumatologic Dermatology Society (2008-2017) Scleroderma Foundation (2009) Skin Cancer Foundation (2007) Society for Investigative Dermatology (2005)
