Download Curriculum Vitae

Education and Trainings

University of Science and Technology of China (USTC)               B.S      1990 

City University of New York (CUNY), New York, NY                    PhD      1996

                    Mentor: David A. Foster, PhD, Rosalyn Yalow Professor 

Harvard Medical School, Boston, MA                                     Postdoctoral 1996-1999

                    Mentor: Timothy A. Springer, PhD, Latham Family Professor, 

                                 Member of National Academy of Sciences


Professional Positions

2010-present, Assistant Professor, Department of Surgery, UT Southwestern Medical Center, Dallas, TX

2007-2010, Instructor, Department of Surgery, UT Southwestern Medical Center, Dallas, TX

2003-2006, Research Scientist, Department of Surgery, UT Southwestern Medical Center, Dallas, TX

2002-2003, Scientist, Reata Pharmaceuticals, Inc., Dallas, TX

1999-2002, Scientist, Biogen-Idec, Cambridge, MA


Univ of Sci and Tech of China , Molecular & Cell Biology
University of Science Technolo , Molecular & Cell Biology
Graduate School
Unlisted - College or Universi (1997)
Graduate School
Central South Univ, Xiang-Ya S (1997)

Research Interest

  • Cardiac autophagy
  • Cardiac inflammation
  • Mitochondria-targeted antioxidant therapy
  • Mitochondrial signaling
  • Sepsis-induced organ dysfunction


Featured Publications LegendFeatured Publications

Mitochondrial ROS Induces Cardiac Inflammation via a Pathway through mtDNA Damage in a Pneumonia-Related Sepsis Model.
Yao X, Carlson D, Sun Y, Ma L, Wolf SE, Minei JP, Zang QS PLoS ONE 2015 10 10 e0139416
Sepsis-induced Cardiac Mitochondrial Damage and Potential Therapeutic Interventions in the Elderly.
Zang QS, Wolf SE, Minei JP Aging Dis 2014 Apr 5 2 137-149
Estrogen-provided Cardiac Protection Following Burn Trauma is Mediated Through a Reduction in Mitochondria-derived DAMPs.
Yao X, Wigginton JG, Maass DL, Ma L, Carlson DL, Wolf SE, Minei JP, Zang QS Am. J. Physiol. Heart Circ. Physiol. 2014 Jan
Specific inhibition of mitochondrial oxidative stress suppresses inflammation and improves cardiac function in a rat pneumonia-related sepsis model.
Zang QS, Sadek H, Maass DL, Martinez B, Ma L, Kilgore JA, Williams NS, Frantz DE, Wigginton JG, Nwariaku FE, Wolf SE, Minei JP Am. J. Physiol. Heart Circ. Physiol. 2012 May 302 9 H1847-59
Sepsis-Induced Cardiac Mitochondrial Dysfunction Involves Altered Mitochondrial-Localization of Tyrosine Kinase Src and Tyrosine Phosphatase SHP2.
Zang QS, Martinez B, Yao X, Maass DL, Ma L, Wolf SE, Minei JP PLoS ONE 2012 7 8 e43424
Regulation of VEGF-induced endothelial cell migration by mitochondrial reactive oxygen species.
Wang Y, Zang QS, Liu Z, Wu Q, Maass D, Dulan G, Shaul PW, Melito L, Frantz DE, Kilgore JA, Williams NS, Terada LS, Nwariaku FE Am. J. Physiol., Cell Physiol. 2011 Sep 301 3 C695-704
Burn serum causes a CD14-dependent mitochondrial damage in primary cardiomyocytes.
Zang QS, Maass DL, Wigginton JG, Barber RC, Martinez B, Idris AH, Horton JW, Nwariaku FE Am. J. Physiol. Heart Circ. Physiol. 2010 Jun 298 6 H1951-8
Cardiac mitochondrial damage and inflammation responses in sepsis.
Zang Q, Maass DL, Tsai SJ, Horton JW Surg Infect (Larchmt) 2007 Feb 8 1 41-54
Cardiac mitochondrial damage and loss of ROS defense after burn injury: the beneficial effects of antioxidant therapy.
Zang Q, Maass DL, White J, Horton JW J. Appl. Physiol. 2007 Jan 102 1 103-12
Selective identification of secreted and transmembrane breast cancer markers using Escherichia coli ampicillin secretion trap.
Ferguson DA, Muenster MR, Zang Q, Spencer JA, Schageman JJ, Lian Y, Garner HR, Gaynor RB, Huff JW, Pertsemlidis A, Ashfaq R, Schorge J, Becerra C, Williams NS, Graff JM Cancer Res. 2005 Sep 65 18 8209-17

Honors & Awards

  • American Heart Association South Central Affiliate
    Beginning-in-aid Grant (2009)

Professional Associations/Affiliations

  • NIH, Surgery, Anesthesiology, and Trauma (SAT) Study Section
  • Shock Society
  • Society of Critical Care Medicine
  • Surgical Infection Society