Skip to Main Content
Naim Maalouf, M.D.

Naim Maalouf, M.D.

Titles and Appointments

Associate Director, Director of the Charles and Jane Pak Center for Mineral Metabolism and Clinical Research

Professor

Endowed Title
The Frederic C. Bartter Professorship in Vitamin D Research
School
Medical School
Department
Internal Medicine | Charles and Jane Pak Center for Mineral Metabolism and Clinical Research

You have reached the Academic Profile.

For more information on the doctor and patient care, please visit the clinical profile.

  • Biography

    Naim Maalouf, M.D., is a Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of its Division of Endocrinology. He specializes in the medical evaluation and management of kidney stones, parathyroid disorders, osteoporosis, bone health in breast cancer, and other mineral metabolism disorders.

    He is the Associate Director of The Charles and Jane Pak Center for Mineral Metabolism and Clinical Research at UTSW.

    Dr. Maalouf holds a bachelor's degree in chemistry from American University of Beirut, where he also earned his medical degree. He completed internal medicine residency training at Emory University in Atlanta, followed by advanced training in endocrinology and metabolism through a fellowship at UT Southwestern.

    Certified by the American Board of Internal Medicine, he joined the UT Southwestern faculty in 2004.

    Dr. Maalouf’s research spans the pathophysiology, prevention, and treatment of kidney stone disease, with a focus on calcium phosphate, calcium oxalate, and uric acid stones. He investigates novel therapies such as hydroxycitrate, the metabolic and dietary contributors to stone formation—including protein intake, obesity, and weight loss—and the development of advanced methods to monitor stone progression. His work also includes optimizing fluid therapy and stent management in both adults and children with nephrolithiasis. Beyond kidney stones, Dr. Maalouf explores broader metabolic and systemic health issues, including the effects of reversing hyperuricemia on metabolic syndrome, the role of renal lipotoxicity in uric acid stone formation, vitamin D’s relationship with type 2 diabetes, the determinants of bone health in HIV-infected individuals and people with cystic fibrosis, and complications of primary hyperparathyroidism, reflecting a comprehensive interest in mineral metabolism and endocrine-related disorders.

    He has been awarded several National Institutes of Health grants and is the principal investigator for the Urinary Stone Disease Research Network site at UT Southwestern. He has delivered scores of presentations and published numerous academic articles.

    Dr. Maalouf is on the editorial board of Urolithiasis and is a member of several professional organizations, including the American Association of Clinical Endocrinologists, the American Society for Bone and Mineral Research, and the Endocrine Society.

    Among his many accolades, Dr. Maalouf earned the Jean D. Wilson Award for Excellence in Scientific Mentorship from the UT Southwestern Division of Endocrinology.

  • Education
    Medical School
    American University of Beirut (1998)
    Internship/Residency
    Emory University School of Medicine (2001), Internal Medicine
    Fellowship
    UT Southwestern Medical Center (2004), Endocrinology & Metabolism
  • Research Interest
    • Nephrolithiasis (Kidney Stone Disease)
    • Osteoporosis
    • Parathyroid Disorders
    • Uric Acid Nephrolithiasis
  • Publications

    Star Featured Publications

    Featured Featured
    Safety of bisphosphonates.
    Orozco C, Maalouf NM Rheum. Dis. Clin. North Am. 2012 Nov 38 4 681-705
    Hypercalciuria associated with high dietary protein intake is not due to acid load.
    Maalouf NM, Moe OW, Adams-Huet B, Sakhaee K J. Clin. Endocrinol. Metab. 2011 Dec 96 12 3733-40
    Metabolic basis for low urine pH in type 2 diabetes.
    Maalouf NM, Cameron MA, Moe OW, Sakhaee K. Clinical Journal of the American Society of Nephrology July 2010 5 1277-1281
    Hypocitraturia and hyperoxaluria after Roux-en-Y gastric bypass surgery.
    Maalouf NM, Tondapu P, Guth ES, Livingston EH, Sakhaee K. Journal of Urology March 2010 183 1026-1030
    The noncalciotropic actions of vitamin D: recent clinical developments
    Maalouf, NM Curr Opin Nephrol Hypertens July 2008 17 408-415
    Severely suppressed bone turnover: a potential complication of alendronate therapy.
    Odvina CV, Zerwekh JE, Rao DS, Maalouf N, Gottschalk FA, Pak CY J. Clin. Endocrinol. Metab. 2005 Mar 90 3 1294-301
  • Honors & Awards
    • Alpha Omega Alpha
      (1998)
  • Professional Associations/Affiliations
    • American Association of Clinical Endocrinologists
    • American Society for Bone and Mineral Research
    • The Endocrine Society