I was born and grew up in Wuhan, China. I obtained my B.S. degree in Biochemistry from Wuhan University. I received my Ph.D. training with Professor Steve Elledge at Baylor College of Medicine (Houston), where I studied the DNA damage checkpoints and developed a novel cloning method called UPS. I went on to do my postdoctoral fellowship with Professor Xiaodong Wang, from whom I learn the art of classical biochemistry. I joined the faculty at UT Southwestern in 2004. My research group currently focuses on understanding the molecular circuits of RNAi/microRNA and sleep regulation by combining genetics and biochemistry.   


Wuhan University (1992), Biochemistry
Graduate School
Baylor College of Medicine (2001), Cell Biology

Research Interest

  • Molecular Mechanism of Fear in Mammals
  • Molecular Mechanism of Sleep in Mammals
  • Molecular Mechanisms of RNA Interference and MicroRNAs


Featured Publications LegendFeatured Publications

The miRNA pathway intrinsically controls self-renewal of Drosophila germline stem cells.
J. Park*, X. Liu*, T. Strauss, D. McKearin, and Q. Liu Curr. Biol. 2007 17 533-538
Dicer-1 and R3D1-L catalyze miRNA maturation in Drosophila
F. Jiang, X. Ye, X. Liu, L. Fincher, D. McKearin, Q. Liu Genes Dev. 2005 19 1674-1679
The univector plasmid-fusion system, a method for rapid construction of recombinant DNA without restriction enzymes.
Q. Liu, M. Z. Li, D. Liebham, D. Cortez, S. J. Elledge Curr. Biol. 1998 8 1300-1309

Honors & Awards

  • Damon Runyon Scholar Award
  • Deborah and W.A. "Tex" Moncrief, Jr. Scholar in Medical Research