As an undergraduate, Dr. Gibson studied biophysics at the University of California at Berkeley. Under the guidance of Dr. John Maunsell, he completed his PhD in 1995 at the University of Rochester, which focused on neocortical activity related to visual processing. Next, he worked under Dr. Barry Connors studying the electrophysiological properties of inhibitory interneurons in somatosensory cortex.

Dr. Gibson joined the Center for Basic Neuroscience at UT Southwestern in 2001. Currently, the lab uses electrophysiological techniques to study the plasticity of cortical inhibitory circuitry and alterations in circuitry in the Fragile X Syndrome mouse model.  A post doc position is currently available, and interested candidates are welcome to contact through email.


Graduate School
University of Rochester (1995)

Research Interest

  • Electrophysiology
  • Neuronal Circuits in Neocortex
  • Neuroscience


Featured Publications LegendFeatured Publications

A Role for Dendritic mGluR5-Mediated Local Translation of Arc/Arg3.1 in MEF2-Dependent Synapse Elimination.
Wilkerson JR, Tsai NP, Maksimova MA, Wu H, Cabalo NP, Loerwald KW, Dictenberg JB, Gibson JR, Huber KM Cell Rep 2014 May
Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome.
Ronesi JA, Collins KA, Hays SA, Tsai NP, Guo W, Birnbaum SG, Hu JH, Worley PF, Gibson JR, Huber KM Nat. Neurosci. 2012 Mar 15 3 431-40, S1
Activity-Dependent Validation of Excitatory versus Inhibitory Synapses by Neuroligin-1 versus Neuroligin-2. Neuron
Chubykin, A.A., Atasoy, D., Etherton, M.R., Brose, N., Kavalali, E.T., Gibson, J.R., Sudhof, T.C. Neuron 2007 54(6) 919-931
A role for the subthreshold currents ILeak and IH in the homeostatic control of excitability in neocortical somatostatin-positive inhibitory neurons
Gibson, J. R., Bartley, A. F., and Huber, K. M. J. Neurophysiol. 2006 96(1) 420-432
Functional Properties of Electrical Synapses Between Inhibitory Neurons of Neocortical Layer 4
Gibson, J. R., Beierlein, M., and Connors, B. W. J. Neurophysiol. 2005 93(1) 467-480

Honors & Awards

  • FRAXA Fellowship
    Research for Fragile X Syndrome (2006)
  • Klingenstein Fellowship
    Award in the Neurosciences (2002)