Laurentiu Pop, M.D. Assistant Professor School Medical School Department Radiation Oncology Biography Certified Principal Investigator by Academy of Clinical Research Professionals (2017) American Board of Medical Laboratory Immunology Diplomate (2013) Residency University of Medicine and Pharmacy, Craiova, Romania, Oncology (2000) Graduate School University of Craiova, Romania, Medicine (1993) Education Medical School University of Craiova Medical (1993), Medicine Research Interest Angiogenesis as a target for cancer therapy B and T regulatory cells Catabolism of immunoglobulins Clinical research in oncology Engineering monoclonal antibodies and immunoconjuates for cancer therapy Immunogenic effect of heavy particle radiation Immunomodulatory effect of radiation therapy Innnate immunity DNA-sensing pathways Mineral metabolism Multidrug resistance in cancer therapy Obesity, inflammation and cancer Pancreatic cancer stem cells Pathophysiology of glomerular filtration Tumor dormancy Type 1 and 2 diabetes Vaccinology Publications Targeted chemotherapy via HER2-based chimeric antigen receptor (CAR) engineered T-cell membrane coated polymeric nanoparticles Yaman S, Ramachandramoorthy H, Iyer P, Chintapula U, Nguyen T, Sabnani M, Kotadia T, Ghaffari S, Pop LM, Hannan R, Weidanz JA, Nguyen KT Bioactive Materials 2024 Apr 34 422-435 Radiation-Induced Innate Neutrophil Response in Tumor Is Mediated by the CXCLs/CXCR2 Axis Zhang F, Mulvaney O, Salcedo E, Manna S, Zhu JZ, Wang T, Ahn C, Pop LM, Hannan R Cancers 2023 Dec 15 Phase 2 Trial of Stereotactic Ablative Radiotherapy for Patients with Primary Renal Cancer Hannan R, McLaughlin MF, Pop LM, Pedrosa I, Kapur P, Garant A, Ahn C, Christie A, Zhu J, Wang T, Robles L, Durakoglugil D, Woldu S, Margulis V, Gahan J, Brugarolas J, Timmerman R, Cadeddu J European urology 2023 Sep 84 275-286 Systemic immune parameters after prior radiation therapy in patients receiving immune checkpoint inhibitors Mundra V, Yang Y, von Itzstein MS, Fattah F, Gonugunta AS, Hannan R, Pop LM, Zhang Y, Wang Y, Sheffield T, Xie Y, Dowell JE, Homsi J, Rashdan S, Park J, Li Q, Wakeland EK, Gerber DE Translational Oncology 2023 Aug 34 Phase II Trial of Sipuleucel-T and Stereotactic Ablative Body Radiation for Patients with Metastatic Castrate-Resistant Prostate Cancer Hannan R, Dohopolski MJ, Pop LM, Mannala S, Watumull L, Womack KB, Gao A, Garant A, Arriaga YE, Bowman I, Chung J, Wang J, Ariizumi K, Ahn C, Timmerman R, Courtney K Biomedicines 2022 Jun 10 Outcome and Immune Correlates of a Phase II Trial of High-Dose Interleukin-2 and Stereotactic Ablative Radiotherapy for Metastatic Renal Cell Carcinoma Hannan R, Mohamad O, Diaz De Leon III A, Manna S, Pop LM, Zhang Z, Mannala S, Christie A, Christley S, Monson N, Ishihara D, Hsu EJ, Ahn C, Kapur P, Chen M, Arriaga YE, Courtney K, Cantarel B, Wakeland EK, Fu Y, Pedrosa I, Cowell L, Wang T, Margulis V, Choy H, Timmerman RD, Brugarolas J Clinical Cancer Research 2021 Dec 27 6716-6725 Transcriptomic analysis links hepatocellular carcinoma (HCC) in HZE ion irradiated mice to a human HCC subtype with favorable outcomes Ding LH, Yu Y, Edmondson EF, Weil MM, Pop LM, McCarthy M, Ullrich RL, Story MD Scientific reports 2021 Dec 11 Renal lipid metabolism abnormalities in obesity and clear cell renal cell carcinoma Bobulescu IA, Pop LM, Mani C, Turner K, Rivera C, Khatoon S, Kairamkonda S, Hannan R, Palle K Metabolites 2021 Sep 11 Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy (PULSAR) in Preclinical Models Enhances Single-Agent Immune Checkpoint Blockade Moore C, Hsu CC, Chen WM, Chen BP, Han C, Story M, Aguilera T, Pop LM, Hannan R, Fu YX, Saha D, Timmerman R International Journal of Radiation Oncology Biology Physics 2021 Aug 110 1306-1316 Neoadjuvant SABR for Renal Cell Carcinoma Inferior Vena Cava Tumor Thrombus—Safety Lead-in Results of a Phase 2 Trial Margulis V, Freifeld Y, Pop LM, Manna S, Kapur P, Pedrosa I, Christie A, Mohamad O, Mannala S, Singla N, Wait M, Bagrodia A, Woldu SL, Gahan J, Brugarolas J, Timmerman R, Hannan R International Journal of Radiation Oncology Biology Physics 2021 Jul 110 1135-1142 Results 1-10 of 40 1 2 3 4 Next Last Books Featured Books Immunotherapy. In Fundamental Immunology Paul W.E. (2003). Lippincott Williams & Wilkins Professional Associations/Affiliations American Association of Immunologists (2005) American Diabetes Association (2016) American Society for Microbiology (2010) Association of Clinical Research Professionals (2017)
