Jayanthi Lea, M.D. Titles and Appointments Interim Vice-Chair of Clinical Operations, Department of Obstetrics and Gynecology Professor & Division Chief Endowed Title Patricia Duniven Fletcher Distinguished Professorship in Gynecological Oncology School Medical School Department Obstetrics and Gynecology Graduate Programs Biomedical Engineering You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Dr. Jayanthi Lea is the DIvision Chief of Gynecologic Oncology and the Director of the Gynecologic Oncology Fellowship Program, in the Department of Obstetrics and Gynecology at UT Southwestern. Board certified both in gynecologic oncology and in obstetrics and gynecology, Dr. Lea is skilled in radical surgical procedures for gynecologic cancers, including cytoreductive surgery for ovarian/ fallopian tube cancers, radical pelvic surgery and minimally invasive, robotic surgery and advanced laparoscopic surgery. Dr. Lea is the Disease Oriented Team Leader for Gynecologic Oncology at the Harold C. Simmons Comprehensive Cancer Center and utilizes a team approach to coordinate and provide comprehensive patient care. She is also the physician champion for the Gynecologic Oncology Previvor Program. Dr. Lea is committed to supporting patients facing gynecologic cancers through every step of their cancer journey, from diagnosis to treatment and beyond. Dr. Lea is dedicated to advancing the field of gynecologic oncology through research and education. She is a member of the National Cancer Institute’s NRG Oncology and Gynecologic Oncology Group (GOG) Foundation/ Partners and serves on the ovarian, cervical and developmental therapeutics subcommittees. Dr. Lea graduated from the University of North Carolina at Chapel Hill with a bachelors of science degree in biology. She received her medical degree from East Carolina University School of Medicine and completed her residency training in obstetrics and gynecology at Riverside Methodist Hospital in Columbus, Ohio. Following a four-year gynecologic oncology fellowship at UT Southwestern Medical Center, she joined the faculty here as a scholar of the NIH Reproductive Scientist Development Program. Dr. Lea investigated the molecular pathogenesis of cervical cancer. Her clinical research interests are in the development of clinical trials for ovarian and cervical cancers using novel therapeutic agents and her basic research interest is in early detection methods for ovarian cancer. She has published several peer reviewed manuscripts on cervical, endometrial and ovarian cancers as well as quality improvement studies in gynecologic oncology. Education Medical School East Carolina University (1996) Internship Riverside Methodist Hospital (1997), Obstetrics & Gynecology Residency Riverside Methodist Hospital (2000), Obstetrics & Gynecology Other Post Graduate Training UT Southwestern (2004) Fellowship UT Southwestern Medical Center (2004), Gynecologic Oncology Research Interest Cervical Cancer Developmental Therapeutics Ovarian Cancer Publications Featured Publications Oxygenation in cervical cancer and normal uterine cervix assessed using blood oxygenation level-dependent (BOLD) MRI at 3T. Hallac RR, Ding Y, Yuan Q, McColl RW, Lea J, Sims RD, Weatherall PT, Mason RP NMR Biomed 2012 Dec 25 12 1321-30 Lymph node metastasis in endometrioid adenocarcinomas of the uterine corpus with occult cervical involvement. Boren T, Lea J, Kehoe S, Miller DS, Richardson D Gynecol. Oncol. 2012 Oct 127 1 43-6 Cervical cancer. Lea JS, Lin KY Obstet. Gynecol. Clin. North Am. 2012 Jun 39 2 233-53 Correlation of cone biopsy with findings at radical hysterectomy and use of adjuvant radiation therapy. Boren TP, Carrick K, Kehoe SM, Lea J, Miller DS, Richardson DL Gynecol. Oncol. 2012 Mar 124 3 508-11 Silencing of HPV 18 Oncoproteins with RNA Interference Causes Growth Inhibition of Cervical Cancer Cells. Lea JS, Sunaga N, Sato M, Kalahasti G, Burbee DG, Minna JD, Muller CY Reproductive Sciences. January 2007 Vol. 14, No.1 20-28 Adenosquamous Histology Predicts Poor Outcome Lea JS, Coleman RL, Garner EO, Duska LR, Miller DS, Schorge JO Gynecologic Oncology 2003 91:558-62 Cervical Adenocarcinoma in situ in Women Younger than Forty Years Lea JS, Shin CH, Sheets EE, Gehrig PA, Coleman RL, Duska LR, Miller DS, Schorge JO Gynecologic Oncology 2002 87:129-132 Stage IIB-IVB Cervical Adenocarcinoma: Prognostic Factors and Survival Lea JS, Wenham RM, Sheets EE, Duska LR, Coleman RL, Miller DS, Schorge JO Gynecologic Oncology 2002 84:115-9 The Role of Para-Aortic Lymph Node Dissection in Early Stage Cervical Adenocarcinoma Lea JS, Sheets EE, Duska LR, Miller DS, Coleman RL, Muller CY, Schorge JO Gynecologic Oncology 2002 285:288 Prognostic indicators of recurrence and treatment-free interval in uterine carcinosarcoma. Vintzileos W, Beer H, Sunkara Y, Pruszynski J, Lea J, Gynecol Oncol 2025 Jun 198 154-160 Results 1-10 of 20 1 2 Next Last Books Featured Books Surgeries for gynecologic malignancies. In Williams Gynecology, 3rd ed. Schorge, J.O., Lea, J.S. (2015). New York, McGraw Hill Vulvar cancer. In Williams Gynecology, 4th ed Lea, J.S. (2020). New York, McGraw-Hill Education Surgeries for gynecologic malignancies. In Williams Gynecology, 4th ed Schorge, J.O., Lea, J.S. (2020). New York, McGraw-Hill Education Gestational Trophoblastic Neoplasia. In Williams Obstetrics Hoffman B., Lea, J.S. (2024). New York, McGraw-Hill Education Honors & Awards FellowAmerican College of Obstetrics and Gynecology (2006) Reproductive Scientist Development Program ScholarNIH K12 Award (2006) Alpha Omega Alpha Honor Society Best Doctors in America Best Doctors in Dallas Best Doctors in North Carolina Best in Category Research AwardAmerican College of Obstetrics and Gynecology Clinical Meeting James F. Nolan Award for Best Scientific PresentationWestern Association of Gynecologic Oncology Texas Super Doctors Texas Super DoctorsTexas Monthly Professional Associations/Affiliations American College of Obstetrics and Gynecology American College of Surgeons (2017) American Society of Clinical Oncology Gynecologic Oncology Group NRG Oncology (2015) Society of Gynecologic Oncology
